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Protein

Phosphoglycerate mutase

Gene

Pgam1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotation
3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotation
Biological processGlycolysisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate mutaseUniRule annotation (EC:5.4.2.11UniRule annotation, EC:5.4.2.4UniRule annotation)
Gene namesi
Name:Pgam1Imported
ORF Names:mCG_113582Imported, mCG_133364Imported, mCG_14289Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97552 Pgam1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ3U7Z6
TopDownProteomicsiQ3U7Z6

Expressioni

Gene expression databases

BgeeiENSMUSG00000011752
ExpressionAtlasiQ3U7Z6 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3U7Z6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0235 Eukaryota
COG0588 LUCA
HOVERGENiHBG027528
KOiK01834
OMAiRMLPYWY
OrthoDBiEOG091G0GIS

Family and domain databases

CDDicd07067 HP_PGM_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
HAMAPiMF_01039 PGAM_GpmA, 1 hit
InterProiView protein in InterPro
IPR013078 His_Pase_superF_clade-1
IPR029033 His_PPase_superfam
IPR001345 PG/BPGM_mutase_AS
IPR005952 Phosphogly_mut1
PANTHERiPTHR11931 PTHR11931, 1 hit
PfamiView protein in Pfam
PF00300 His_Phos_1, 2 hits
SMARTiView protein in SMART
SM00855 PGAM, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit
TIGRFAMsiTIGR01258 pgm_1, 1 hit
PROSITEiView protein in PROSITE
PS00175 PG_MUTASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q3U7Z6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYKLVLIR HGESAWNLEN RFSGWYDADL SPAGHEEAKR GGQALRDAGY
60 70 80 90 100
EFDICFTSVQ KRAIRTLWTV LDAIDQMWLP VVRTWRLNER HYGGLTGLNK
110 120 130 140 150
AETAAKHGEA QVKIWRRSYD VPPPPMEPDH PFYSNISKDR RYADLTEDQL
160 170 180 190 200
PSCESLKDTI ARALPFWNEE IVPQIKEGKR VLIAAHGNSL RGIVKHLEGL
210 220 230 240 250
SEEAIMELNL PTGIPIVYEL DKNLKPIKPM QFLGDEETVR KAMEAVAAQG

KVKK
Length:254
Mass (Da):28,832
Last modified:October 11, 2005 - v1
Checksum:i6DC09A3BEBB22409
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106139 mRNA Translation: AAI06140.1
AK150716 mRNA Translation: BAE29794.1
AK152443 mRNA Translation: BAE31223.1
AK153202 mRNA Translation: BAE31802.1
AK159305 mRNA Translation: BAE34975.1
AK165410 mRNA Translation: BAE38168.1
AK168949 mRNA Translation: BAE40755.1
CH466577 Genomic DNA Translation: EDL05155.1
CH466593 Genomic DNA Translation: EDL24186.1
CH466534 Genomic DNA Translation: EDL41865.1
RefSeqiNP_075907.2, NM_023418.2
UniGeneiMm.16783
Mm.391589

Genome annotation databases

GeneIDi18648
KEGGimmu:18648

Similar proteinsi

Entry informationi

Entry nameiQ3U7Z6_MOUSE
AccessioniPrimary (citable) accession number: Q3U7Z6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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