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Protein

Phosphoglycerate mutase

Gene

Pgam1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

2,3-bisphospho-D-glycerate + H2O = 3-phospho-D-glycerate + phosphate.UniRule annotation
2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotation
3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

GlycolysisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate mutaseUniRule annotation (EC:3.1.3.13UniRule annotation, EC:5.4.2.11UniRule annotation, EC:5.4.2.4UniRule annotation)
Gene namesi
Name:Pgam1Imported
ORF Names:mCG_113582Imported, mCG_133364Imported, mCG_14289Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97552. Pgam1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

TopDownProteomicsiQ3U7Z6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000011752.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000011896.

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0235. Eukaryota.
COG0588. LUCA.
HOVERGENiHBG027528.
KOiK01834.
OMAiFEFDICY.
OrthoDBiEOG091G0GIS.

Family and domain databases

CDDicd07067. HP_PGM_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA. 1 hit.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 2 hits.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3U7Z6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYKLVLIR HGESAWNLEN RFSGWYDADL SPAGHEEAKR GGQALRDAGY
60 70 80 90 100
EFDICFTSVQ KRAIRTLWTV LDAIDQMWLP VVRTWRLNER HYGGLTGLNK
110 120 130 140 150
AETAAKHGEA QVKIWRRSYD VPPPPMEPDH PFYSNISKDR RYADLTEDQL
160 170 180 190 200
PSCESLKDTI ARALPFWNEE IVPQIKEGKR VLIAAHGNSL RGIVKHLEGL
210 220 230 240 250
SEEAIMELNL PTGIPIVYEL DKNLKPIKPM QFLGDEETVR KAMEAVAAQG

KVKK
Length:254
Mass (Da):28,832
Last modified:October 11, 2005 - v1
Checksum:i6DC09A3BEBB22409
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106139 mRNA. Translation: AAI06140.1.
AK150716 mRNA. Translation: BAE29794.1.
AK152443 mRNA. Translation: BAE31223.1.
AK153202 mRNA. Translation: BAE31802.1.
AK159305 mRNA. Translation: BAE34975.1.
AK165410 mRNA. Translation: BAE38168.1.
AK168949 mRNA. Translation: BAE40755.1.
CH466577 Genomic DNA. Translation: EDL05155.1.
CH466593 Genomic DNA. Translation: EDL24186.1.
CH466534 Genomic DNA. Translation: EDL41865.1.
RefSeqiNP_075907.2. NM_023418.2.
UniGeneiMm.16783.
Mm.391589.

Genome annotation databases

GeneIDi18648.
KEGGimmu:18648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC106139 mRNA. Translation: AAI06140.1.
AK150716 mRNA. Translation: BAE29794.1.
AK152443 mRNA. Translation: BAE31223.1.
AK153202 mRNA. Translation: BAE31802.1.
AK159305 mRNA. Translation: BAE34975.1.
AK165410 mRNA. Translation: BAE38168.1.
AK168949 mRNA. Translation: BAE40755.1.
CH466577 Genomic DNA. Translation: EDL05155.1.
CH466593 Genomic DNA. Translation: EDL24186.1.
CH466534 Genomic DNA. Translation: EDL41865.1.
RefSeqiNP_075907.2. NM_023418.2.
UniGeneiMm.16783.
Mm.391589.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000011896.

Proteomic databases

TopDownProteomicsiQ3U7Z6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi18648.
KEGGimmu:18648.

Organism-specific databases

CTDi5223.
MGIiMGI:97552. Pgam1.

Phylogenomic databases

eggNOGiKOG0235. Eukaryota.
COG0588. LUCA.
HOVERGENiHBG027528.
KOiK01834.
OMAiFEFDICY.
OrthoDBiEOG091G0GIS.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000011752.

Family and domain databases

CDDicd07067. HP_PGM_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA. 1 hit.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 2 hits.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3U7Z6_MOUSE
AccessioniPrimary (citable) accession number: Q3U7Z6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.