Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q3U6U5 (GTPB6_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative GTP-binding protein 6
Gene names
Name:Gtpbp6
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length514 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Cofactor

Magnesium By similarity.

Sequence similarities

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.

Contains 1 Hflx-type G (guanine nucleotide-binding) domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 514514Putative GTP-binding protein 6
PRO_0000304799

Regions

Domain285 – 449165Hflx-type G

Sites

Metal binding2981Magnesium By similarity
Metal binding3191Magnesium By similarity

Experimental info

Sequence conflict3501N → S in BAE26076. Ref.1
Sequence conflict3501N → S in BAE35103. Ref.1
Sequence conflict5011R → G in BAE35103. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q3U6U5 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 95774C6439C0B3E6

FASTA51456,475
        10         20         30         40         50         60 
MLFLRAAVLP GFWLPRVRRV QLVRSPAVTL PSPVRTVHAG SRVWGSAWAG GGPVRGGGEE 

        70         80         90        100        110        120 
DPREDEEEEE DELLRAPPLL PLDTQRVCVL HPDVKRPAGK KPRSTAEWQV AEAAALVRAL 

       130        140        150        160        170        180 
PGWSVASTLV VPSAAPGSRL VFGKGNFQDV TEKIKGCQDI TSVFLNVERM APPTKKELES 

       190        200        210        220        230        240 
AWGLRVFDRF TLVLHIFRCN ARTREARMQL ALAEIPLLRS SVNTDSGQQD QQGWGSRYIM 

       250        260        270        280        290        300 
GSGESPTELR ARALRDRELR LRRVLERLRD KRRLMRKERV RREFPVVSVV GYTNCGKTTL 

       310        320        330        340        350        360 
IQALTGEAAL QPRDQPFATL DVTVHAGLLP SRLRILYVDT IGFLSQLPHN LIHAFSATLE 

       370        380        390        400        410        420 
DVAYSDVLVH VTDVSHPDAE LQKATVLSTL RGLHLPPALL ESALEVHSKV DLVPGYTPPC 

       430        440        450        460        470        480 
SGALAVSAIS GRGLDELKAA LEASVLRATG RQVLTLCVRL GGPQLGWLYK EAVVQQVQEL 

       490        500        510 
PEGDAAHVTV VITQAAYGRF RKLFPIDAPS ALPH 

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Bone marrow and Lung.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK144812 mRNA. Translation: BAE26076.1.
AK152225 mRNA. Translation: BAE31052.1.
AK152972 mRNA. Translation: BAE31629.1.
AK159462 mRNA. Translation: BAE35103.1.
CCDSCCDS51604.1.
RefSeqNP_660129.2. NM_145147.5.
UniGeneMm.86267.

3D structure databases

ProteinModelPortalQ3U6U5.
SMRQ3U6U5. Positions 149-438.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ3U6U5.

Proteomic databases

PaxDbQ3U6U5.
PRIDEQ3U6U5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000077220; ENSMUSP00000076458; ENSMUSG00000033434.
GeneID107999.
KEGGmmu:107999.
UCSCuc008ypr.2. mouse.

Organism-specific databases

CTD8225.
MGIMGI:1306825. Gtpbp6.

Phylogenomic databases

eggNOGCOG2262.
GeneTreeENSGT00390000001397.
HOGENOMHOG000260368.
HOVERGENHBG052970.
InParanoidQ3U6U5.
OrthoDBEOG7WHH9P.
TreeFamTF315022.

Gene expression databases

BgeeQ3U6U5.
CleanExMM_GTPBP6.
GenevestigatorQ3U6U5.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR006073. GTP_binding_domain.
IPR016496. GTPase_HflX.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR10229. PTHR10229. 1 hit.
PfamPF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFPIRSF006809. GTP-binding_hflX_prd. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR03156. GTP_HflX. 1 hit.
PROSITEPS51705. G_HFLX. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio359857.
PROQ3U6U5.
SOURCESearch...

Entry information

Entry nameGTPB6_MOUSE
AccessionPrimary (citable) accession number: Q3U6U5
Secondary accession number(s): Q3TX13, Q3UMM2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 11, 2005
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot