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Protein
Submitted name:

Aryl hydrocarbon receptor

Gene

Ahr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aryl hydrocarbon receptorImported
Gene namesi
Name:AhrImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:105043. Ahr.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112137.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini26 – 7954BHLH (basic helix-loop-helix)InterPro annotationAdd
BLAST
Domaini116 – 17964PAS (PER-ARNT-SIM)InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 basic helix-loop-helix (bHLH) domain.UniRule annotation
Contains PAC (PAS-associated C-terminal) domain.SAAS annotation
Contains PAS (PER-ARNT-SIM) domains.SAAS annotation
Contains bHLH (basic helix-loop-helix) domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG3560. Eukaryota.
ENOG410XRZH. LUCA.
GeneTreeiENSGT00800000124106.
HOGENOMiHOG000252935.
HOVERGENiHBG007313.
KOiK09093.
OMAiQQLCQKM.
OrthoDBiEOG793BBM.
TreeFamiTF352074.

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR033348. AHR.
IPR011598. bHLH_dom.
IPR001610. PAC.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR013655. PAS_fold_3.
[Graphical view]
PANTHERiPTHR10649:SF9. PTHR10649:SF9. 1 hit.
PfamiPF00010. HLH. 1 hit.
PF00989. PAS. 1 hit.
PF08447. PAS_3. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
SM00086. PAC. 1 hit.
SM00091. PAS. 2 hits.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
SSF55785. SSF55785. 2 hits.
PROSITEiPS50888. BHLH. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3U5D9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSGANITYA SRKRRKPVQK TVKPIPAEGI KSNPSKRHRD RLNTELDRLA
60 70 80 90 100
SLLPFPQDVI NKLDKLSVLR LSVSYLRAKS FFDVALKSTP ADRNGGQDQC
110 120 130 140 150
RAQIRDWQDL QEGEFLLQAL NGFVLVVTAD ALVFYASSTI QDYLGFQQSD
160 170 180 190 200
VIHQSVYELI HTEDRAEFQR QLHWALNPDS AQGVDEAHGP PQAAVYYTPD
210 220 230 240 250
QLPPENASFM ERCFRCRLRC LLDNSSGFLA MNFQGRLKYL HGQNKKGKDG
260 270 280 290 300
ALLPPQLALF AIATPLQPPS ILEIRTKNFI FRTKHKLDFT PIGCDAKGQL
310 320 330 340 350
ILGYTEVELC TRGSGYQFIH AADILHCAES HIRMIKTGES GMTVFRLLAK
360 370 380 390 400
HSRWRWVQSN ARLIYRNGRP DYIIATQRPL TDEEGREHLQ KRSTSLPFMF
410 420 430 440 450
ATGEAVLYEI SSPFSPIMDP LPIRTKSNTS RKDWAPQSTP SKDSFHPSSL
460 470 480 490 500
MSALIQQDES IYLCPPSSPA LLDSHFLMGS VSKCGSWQDS FAAAGSEAAL
510 520 530 540 550
KHEQIGHAQD VNLALSGGPS ELFPDNKNND LYSIMRNLGI DFEDIRSMQN
560 570 580 590 600
EEFFRTDSTA AGEVDFKDID ITDEILTYVQ DSLNNSTLLN SACQQQPVTQ
610 620 630 640 650
HLSCMLQERL QLEQQQQLQQ PPPQALEPQQ QLCQMVCPQQ DLGPKHTQIN
660 670 680 690 700
GTFASWNPTP PVSFNCPQQE LKHYQLFSSL QGTAQEFPYK PEVDSVPYTQ
710 720 730 740 750
NFAPCNQPLL PEHSKSVQLD FPGRDFEPSL HPTTSNLDFV SCLQVPENQS
760 770 780 790 800
HGINSQSAMV SPQAYYAGAM SMYQCQPGPQ RTPVDQTQYS SEIPGSQAFL

SKVQS
Length:805
Mass (Da):90,338
Last modified:October 11, 2005 - v1
Checksum:iCC36B58C6BE780C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159635 Genomic DNA. No translation available.
AK153678 mRNA. Translation: BAE32140.1.
RefSeqiNP_001300956.1. NM_001314027.1.
NP_038492.1. NM_013464.4.
UniGeneiMm.341377.

Genome annotation databases

EnsembliENSMUST00000116436; ENSMUSP00000112137; ENSMUSG00000019256.
GeneIDi11622.
KEGGimmu:11622.
UCSCiuc007nji.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159635 Genomic DNA. No translation available.
AK153678 mRNA. Translation: BAE32140.1.
RefSeqiNP_001300956.1. NM_001314027.1.
NP_038492.1. NM_013464.4.
UniGeneiMm.341377.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112137.

Protocols and materials databases

DNASUi11622.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000116436; ENSMUSP00000112137; ENSMUSG00000019256.
GeneIDi11622.
KEGGimmu:11622.
UCSCiuc007nji.1. mouse.

Organism-specific databases

CTDi196.
MGIiMGI:105043. Ahr.

Phylogenomic databases

eggNOGiKOG3560. Eukaryota.
ENOG410XRZH. LUCA.
GeneTreeiENSGT00800000124106.
HOGENOMiHOG000252935.
HOVERGENiHBG007313.
KOiK09093.
OMAiQQLCQKM.
OrthoDBiEOG793BBM.
TreeFamiTF352074.

Miscellaneous databases

ChiTaRSiAhr. mouse.
SOURCEiSearch...

Family and domain databases

Gene3Di4.10.280.10. 1 hit.
InterProiIPR033348. AHR.
IPR011598. bHLH_dom.
IPR001610. PAC.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR013655. PAS_fold_3.
[Graphical view]
PANTHERiPTHR10649:SF9. PTHR10649:SF9. 1 hit.
PfamiPF00010. HLH. 1 hit.
PF00989. PAS. 1 hit.
PF08447. PAS_3. 1 hit.
[Graphical view]
SMARTiSM00353. HLH. 1 hit.
SM00086. PAC. 1 hit.
SM00091. PAS. 2 hits.
[Graphical view]
SUPFAMiSSF47459. SSF47459. 1 hit.
SSF55785. SSF55785. 2 hits.
PROSITEiPS50888. BHLH. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: ThymusImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3U5D9_MOUSE
AccessioniPrimary (citable) accession number: Q3U5D9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 6, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.