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Protein
Submitted name:

Aryl hydrocarbon receptor

Gene

Ahr

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-211945 Phase I - Functionalization of compounds
R-MMU-211976 Endogenous sterols
R-MMU-211981 Xenobiotics
R-MMU-8937144 Aryl hydrocarbon receptor signalling

Names & Taxonomyi

Protein namesi
Submitted name:
Aryl hydrocarbon receptorImported
Gene namesi
Name:AhrImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:105043 Ahr

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000019256

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 79BHLHInterPro annotationAdd BLAST54
Domaini116 – 179PASInterPro annotationAdd BLAST64

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG3560 Eukaryota
ENOG410XRZH LUCA
GeneTreeiENSGT00910000144132
HOGENOMiHOG000252935
HOVERGENiHBG007313
KOiK09093
OMAiQQLCQKM
OrthoDBiEOG091G16AJ
TreeFamiTF352074

Family and domain databases

CDDicd00083 HLH, 1 hit
cd00130 PAS, 2 hits
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR033348 AHR
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR001610 PAC
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013767 PAS_fold
IPR013655 PAS_fold_3
PANTHERiPTHR10649:SF9 PTHR10649:SF9, 1 hit
PfamiView protein in Pfam
PF00010 HLH, 1 hit
PF00989 PAS, 1 hit
PF08447 PAS_3, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SM00086 PAC, 1 hit
SM00091 PAS, 2 hits
SUPFAMiSSF47459 SSF47459, 1 hit
SSF55785 SSF55785, 2 hits
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS50112 PAS, 1 hit

Sequencei

Sequence statusi: Complete.

Q3U5D9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSGANITYA SRKRRKPVQK TVKPIPAEGI KSNPSKRHRD RLNTELDRLA
60 70 80 90 100
SLLPFPQDVI NKLDKLSVLR LSVSYLRAKS FFDVALKSTP ADRNGGQDQC
110 120 130 140 150
RAQIRDWQDL QEGEFLLQAL NGFVLVVTAD ALVFYASSTI QDYLGFQQSD
160 170 180 190 200
VIHQSVYELI HTEDRAEFQR QLHWALNPDS AQGVDEAHGP PQAAVYYTPD
210 220 230 240 250
QLPPENASFM ERCFRCRLRC LLDNSSGFLA MNFQGRLKYL HGQNKKGKDG
260 270 280 290 300
ALLPPQLALF AIATPLQPPS ILEIRTKNFI FRTKHKLDFT PIGCDAKGQL
310 320 330 340 350
ILGYTEVELC TRGSGYQFIH AADILHCAES HIRMIKTGES GMTVFRLLAK
360 370 380 390 400
HSRWRWVQSN ARLIYRNGRP DYIIATQRPL TDEEGREHLQ KRSTSLPFMF
410 420 430 440 450
ATGEAVLYEI SSPFSPIMDP LPIRTKSNTS RKDWAPQSTP SKDSFHPSSL
460 470 480 490 500
MSALIQQDES IYLCPPSSPA LLDSHFLMGS VSKCGSWQDS FAAAGSEAAL
510 520 530 540 550
KHEQIGHAQD VNLALSGGPS ELFPDNKNND LYSIMRNLGI DFEDIRSMQN
560 570 580 590 600
EEFFRTDSTA AGEVDFKDID ITDEILTYVQ DSLNNSTLLN SACQQQPVTQ
610 620 630 640 650
HLSCMLQERL QLEQQQQLQQ PPPQALEPQQ QLCQMVCPQQ DLGPKHTQIN
660 670 680 690 700
GTFASWNPTP PVSFNCPQQE LKHYQLFSSL QGTAQEFPYK PEVDSVPYTQ
710 720 730 740 750
NFAPCNQPLL PEHSKSVQLD FPGRDFEPSL HPTTSNLDFV SCLQVPENQS
760 770 780 790 800
HGINSQSAMV SPQAYYAGAM SMYQCQPGPQ RTPVDQTQYS SEIPGSQAFL

SKVQS
Length:805
Mass (Da):90,338
Last modified:October 11, 2005 - v1
Checksum:iCC36B58C6BE780C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159635 Genomic DNA No translation available.
AK153678 mRNA Translation: BAE32140.1
RefSeqiNP_001300956.1, NM_001314027.1
NP_038492.1, NM_013464.4
UniGeneiMm.341377

Genome annotation databases

EnsembliENSMUST00000116436; ENSMUSP00000112137; ENSMUSG00000019256
GeneIDi11622
KEGGimmu:11622
UCSCiuc007nji.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ3U5D9_MOUSE
AccessioniPrimary (citable) accession number: Q3U5D9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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