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Protein

Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2

Gene

Pyroxd2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Probable oxidoreductase.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi38 – 71FADSequence analysisAdd BLAST34

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 (EC:1.-.-.-)
Gene namesi
Name:Pyroxd2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1921830. Pyroxd2.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002440721 – 581Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2Add BLAST581

Proteomic databases

MaxQBiQ3U4I7.
PaxDbiQ3U4I7.
PeptideAtlasiQ3U4I7.
PRIDEiQ3U4I7.

PTM databases

iPTMnetiQ3U4I7.
PhosphoSitePlusiQ3U4I7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000060224.
CleanExiMM_4833409A17RIK.
GenevisibleiQ3U4I7. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075825.

Structurei

3D structure databases

ProteinModelPortaliQ3U4I7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4254. Eukaryota.
COG1233. LUCA.
GeneTreeiENSGT00390000011684.
InParanoidiQ3U4I7.
OMAiRWFESEP.
OrthoDBiEOG091G044J.
TreeFamiTF315188.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
InterProiView protein in InterPro
IPR002937. Amino_oxidase.
IPR036188. FAD/NAD-bd_sf.
PfamiView protein in Pfam
PF01593. Amino_oxidase. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.

Sequencei

Sequence statusi: Complete.

Q3U4I7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGGRGLIR ALHSSPCPTW KRAQSGANGR LKPEYDAVVI GAGHNGLVAA
60 70 80 90 100
AYLQRLGVNT AVFERRHVIG GAAVTEEIIP GFKFSRASYL LSLLRPQICT
110 120 130 140 150
DLELKKHGLK LHLRDPYSFT PMLEEGTLNR LPRSLLLGTD MAANQKEISQ
160 170 180 190 200
FSRKDAQAFP RYEEFMKRLV LAIDPLLDAA PVDTTAFQHG SLLQRLRALS
210 220 230 240 250
TLKPLLKAGR TLGAQLPQYY EVLTAPISKV LDQRFESEPL KATLATDAVI
260 270 280 290 300
GAMTSPHTPG SGYVLLHHVM GSLEGTQGAW SYVQGGMGAL SDAIASSAAT
310 320 330 340 350
RGASIFTEKT VAKVQVNSEG RAQGVTLQDG EEVRSRVVLS CASPQVTFLE
360 370 380 390 400
LTPQEWLPGA FVKRISQLDT QSPVTKINVA VDRLPNFQAA PNAPGDQPQG
410 420 430 440 450
HHQCSIHLNC EDTLLLHQAF EDAKGGLPSQ KPMIELCIPS SLDPTLAPPG
460 470 480 490 500
CHVVSLFTQY TPYTLAGGKV WNEQEKNTYA DKVFDCIEAY APGFKRSVLA
510 520 530 540 550
RDILTPPDLE RIFRLPGGNI FHGAMSLDQL YFARPVPQHS DYRCPVQGLY
560 570 580
LCGSGAHPGG GVMGAAGRNA AHVVFRDLKN M
Length:581
Mass (Da):62,940
Last modified:September 18, 2013 - v3
Checksum:i8BC394516E5AB468
GO

Sequence cautioni

Q3U4I7: The sequence BAE32444 differs from that shown. Intron retention between positions 50 and 165.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti19T → A in BAE32444 (PubMed:16141072).Curated1
Sequence conflicti73A → R in BAB29495 (PubMed:16141072).Curated1
Sequence conflicti106 – 115KHGLKLHLRD → VDRLAWPGGW in BAC29991 (PubMed:16141072).Curated10

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014668 mRNA. Translation: BAB29495.1.
AK038414 mRNA. Translation: BAC29991.1.
AK154222 mRNA. Translation: BAE32444.1. Sequence problems.
AC125458 Genomic DNA. No translation available.
CCDSiCCDS37991.1.
RefSeqiNP_083287.2. NM_029011.2.
UniGeneiMm.329858.

Genome annotation databases

EnsembliENSMUST00000076505; ENSMUSP00000075825; ENSMUSG00000060224.
GeneIDi74580.
KEGGimmu:74580.
UCSCiuc008hnu.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiPYRD2_MOUSE
AccessioniPrimary (citable) accession number: Q3U4I7
Secondary accession number(s): E9QPD2, Q8CAN2, Q9D630
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: September 18, 2013
Last modified: October 25, 2017
This is version 93 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families