Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CD274 antigen

Gene

Cd274

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD274 antigenImported
Submitted name:
PD-L1Imported
Gene namesi
Name:Cd274Imported
ORF Names:mCG_9108Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1926446. Cd274.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei240 – 260HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501109883219 – 290Sequence analysisAdd BLAST272

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000016496.

Structurei

3D structure databases

SMRiQ3U472.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 127Ig-likeInterPro annotationAdd BLAST95
Domaini133 – 224Ig-likeInterPro annotationAdd BLAST92

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IIBU. Eukaryota.
ENOG4111V14. LUCA.
HOVERGENiHBG082112.
KOiK06745.
OMAiIWTSSDH.
OrthoDBiEOG091G0F5W.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR013162. CD80_C2-set.
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
PfamiView protein in Pfam
PF08205. C2-set_2. 1 hit.
PF07686. V-set. 1 hit.
SMARTiView protein in SMART
SM00409. IG. 2 hits.
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 2 hits.

Sequencei

Sequence statusi: Complete.

Q3U472-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIFAGIIFT ACCHLLRAFT ITAPKDLYVV EYGSNVTMEC RFPVERELDL
60 70 80 90 100
LALVVYWEKE DEQVIQFVAG EEDLKPQHSN FRGRASLPKD QLLKGNAALQ
110 120 130 140 150
ITDVKLQDAG VYCCIISYGG ADYKRITLKV NAPYRKINQR ISVDPATSEH
160 170 180 190 200
ELICQAEGYP EAEVIWTNSD HQPVSGKRSV TTSRTEGMLL NVTSSLRVNA
210 220 230 240 250
TANDVFYCTF WRSQPGQNHT AELIIPELPA THPPQNRTHW VLLGSILLFL
260 270 280 290
IVVSTVLLFL RKQVRMLDVE KCGVEDTSSK NRNDTQFEET
Length:290
Mass (Da):32,780
Last modified:October 11, 2005 - v1
Checksum:iAB7C46CF853EBB02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ904196 mRNA. Translation: ADK70950.1.
AK154403 mRNA. Translation: BAE32562.1.
CH466534 Genomic DNA. Translation: EDL41681.1.
RefSeqiNP_068693.1. NM_021893.3.
UniGeneiMm.245363.

Genome annotation databases

GeneIDi60533.
KEGGimmu:60533.

Similar proteinsi

Entry informationi

Entry nameiQ3U472_MOUSE
AccessioniPrimary (citable) accession number: Q3U472
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 22, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)