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Protein
Submitted name:

Protein Cln6

Gene

Cln6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein homodimerization activity Source: UniProtKB

GO - Biological processi

  1. cellular macromolecule catabolic process Source: MGI
  2. cholesterol metabolic process Source: UniProtKB
  3. ganglioside metabolic process Source: UniProtKB
  4. glycosaminoglycan metabolic process Source: UniProtKB
  5. locomotion involved in locomotory behavior Source: MGI
  6. lysosomal lumen acidification Source: UniProtKB
  7. lysosome organization Source: MGI
  8. positive regulation of proteolysis Source: UniProtKB
  9. visual perception Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Cln6Imported
Gene namesi
Name:Cln6Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2159324. Cln6.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB
  2. endoplasmic reticulum lumen Source: UniProtKB
  3. intracellular membrane-bounded organelle Source: MGI
  4. membrane Source: MGI
  5. nuclear membrane Source: MGI
  6. nucleoplasm Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiQ3U466.
PRIDEiQ3U466.

PTM databases

PhosphoSiteiQ3U466.

Expressioni

Gene expression databases

BgeeiQ3U466.
ExpressionAtlasiQ3U466. baseline and differential.
GenevestigatoriQ3U466.

Structurei

3D structure databases

ProteinModelPortaliQ3U466.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00400000022240.
HOGENOMiHOG000013091.
HOVERGENiHBG039396.
InParanoidiQ3U466.
KOiK12359.
OMAiCKAESHM.
OrthoDBiEOG70S764.
PhylomeDBiQ3U466.
TreeFamiTF333294.

Family and domain databases

InterProiIPR029255. CLN6.
[Graphical view]
PfamiPF15156. CLN6. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3U466-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAATRRRQL LGAAGGPGVA FVQARHGSVK AEDKDRTAPF HLDLWFYFTL
60 70 80 90 100
QNWVLDFGRP IAMLVFPIQW FPLNKPSVGD YFHMTYNIIT PFLLLKLIER
110 120 130 140 150
SPRTLPRSIV YVSIITFIMG ASIHLVGDSV NHRLLFSGYQ HHLSVRENPI
160 170 180 190 200
IKNLKPETLI DSFELLYYYD EYLGHCMWYI PFFLILFMYF SGCFTTCKAE
210 220 230 240 250
SHMPGPALLL VVPSGLYYWY LVTEGQIFIL FIFTFFAMLA LVLHQKRRRL
260 270 280 290 300
FLDSNGLFLL YSFALTLSLV ALWVAWLWND PVLRKKYPGV IYVPEPWAFY

TLHVSSQQ
Length:308
Mass (Da):35,859
Last modified:October 11, 2005 - v1
Checksum:i6F82E16DF1E6A7BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164614 Genomic DNA. No translation available.
AK154414 mRNA. Translation: BAE32568.1.
RefSeqiNP_001028347.1. NM_001033175.2.
UniGeneiMm.283636.

Genome annotation databases

EnsembliENSMUST00000034776; ENSMUSP00000034776; ENSMUSG00000032245.
GeneIDi76524.
KEGGimmu:76524.
UCSCiuc009qan.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164614 Genomic DNA. No translation available.
AK154414 mRNA. Translation: BAE32568.1.
RefSeqiNP_001028347.1. NM_001033175.2.
UniGeneiMm.283636.

3D structure databases

ProteinModelPortaliQ3U466.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ3U466.

Proteomic databases

MaxQBiQ3U466.
PRIDEiQ3U466.

Protocols and materials databases

DNASUi76524.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000034776; ENSMUSP00000034776; ENSMUSG00000032245.
GeneIDi76524.
KEGGimmu:76524.
UCSCiuc009qan.1. mouse.

Organism-specific databases

CTDi54982.
MGIiMGI:2159324. Cln6.

Phylogenomic databases

GeneTreeiENSGT00400000022240.
HOGENOMiHOG000013091.
HOVERGENiHBG039396.
InParanoidiQ3U466.
KOiK12359.
OMAiCKAESHM.
OrthoDBiEOG70S764.
PhylomeDBiQ3U466.
TreeFamiTF333294.

Miscellaneous databases

ChiTaRSiCln6. mouse.
NextBioi345318.
PROiQ3U466.
SOURCEiSearch...

Gene expression databases

BgeeiQ3U466.
ExpressionAtlasiQ3U466. baseline and differential.
GenevestigatoriQ3U466.

Family and domain databases

InterProiIPR029255. CLN6.
[Graphical view]
PfamiPF15156. CLN6. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2000)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2004)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3U466_MOUSE
AccessioniPrimary (citable) accession number: Q3U466
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 1, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.