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Protein

X-ray radiation resistance-associated protein 1

Gene

Xrra1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the response of cells to X-ray radiation.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
X-ray radiation resistance-associated protein 1
Gene namesi
Name:Xrra1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:2181647. Xrra1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003181321 – 786X-ray radiation resistance-associated protein 1Add BLAST786

Proteomic databases

PaxDbiQ3U3V8.
PRIDEiQ3U3V8.

PTM databases

iPTMnetiQ3U3V8.
PhosphoSitePlusiQ3U3V8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000035211.
CleanExiMM_XRRA1.
ExpressionAtlasiQ3U3V8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035929.

Structurei

3D structure databases

ProteinModelPortaliQ3U3V8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati146 – 158LRR 1Add BLAST13
Repeati169 – 192LRR 2Add BLAST24
Repeati193 – 214LRR 3Add BLAST22
Repeati234 – 255LRR 4Add BLAST22
Repeati259 – 280LRR 5Add BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili714 – 738Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coil, Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00390000016048.
HOGENOMiHOG000060299.
HOVERGENiHBG108685.
InParanoidiQ3U3V8.
OMAiFMDEFCQ.
OrthoDBiEOG091G0G3O.
PhylomeDBiQ3U3V8.
TreeFamiTF329758.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiView protein in InterPro
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
SMARTiView protein in SMART
SM00369. LRR_TYP. 4 hits.
SUPFAMiSSF52058. SSF52058. 2 hits.
PROSITEiView protein in PROSITE
PS51450. LRR. 5 hits.

Sequencei

Sequence statusi: Complete.

Q3U3V8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSSGMYKMD NGKPCLNNCF PAKSLLRLPE EGRGHWIVVR KGSMKKGAAK
60 70 80 90 100
ASTEGQESQK KVSFDTGLKK ISRRDSQADV LGHILDRSFL LKHHSARKPS
110 120 130 140 150
DLCTINVSGM KFSKAKEKDF KHFTSVIYIN ASENLLPLDV FHTFPVLKEL
160 170 180 190 200
ELAFNGIKMV YVKYGDFKTL EFLDLSFNSL TEEAICDLGI LPHLRVLLLT
210 220 230 240 250
GNGLTSLPPN MAVKEQEASM TSLTSKKYIL RFPALETLML DDNKLSNPSC
260 270 280 290 300
FASLAGLRRL KKLSLDQNKI VRIPYLQQIQ LRDGSGDWVT EGPNPQKELQ
310 320 330 340 350
PQMWIFETPD EQPNYTVLPM KKDVDRTEVV FSSYPGFSTS ETAKVCSLPP
360 370 380 390 400
MFEILPVKSL KARNQTLAPP FPELRYLSLA YNKIAKEDAV LPAALFPSLC
410 420 430 440 450
ELVFHNNPLV AHTRGIPPLL KSFLQDRLGI RLVRKKLVKP KHHMLMPRKE
460 470 480 490 500
SRKVKTYIPK VPKHSLVPHH LNMITDSPPS SLMPEPEHST EDTSHEALFA
510 520 530 540 550
NEGPEGPSLT HRAFVPMPPI CSDSTVHSEA VSHQSHTAGL VSSEHPSDDD
560 570 580 590 600
AKSTESIFLT QVNELPSSTA HRENLEAVND QRRPSTAPRE TKRTRRKQTA
610 620 630 640 650
TSLHNKYDGY EELLTVKPDP AFLEPKGIQK NAQALHRMLK QPLICRSSKP
660 670 680 690 700
RLDTFQKPYV PKEKRAGRIP ILPPRKTRAQ LLDDILIRMR DPRNVTEAPL
710 720 730 740 750
GTVLQRRAQQ RLVNQKQYRE AKRLLKEFRA RYRQLVRSSL RTVFAASPPP
760 770 780
RPPTRRALSA GQPKLGRFLE FMDEFCQEPT ASDSKE
Length:786
Mass (Da):88,884
Last modified:October 11, 2005 - v1
Checksum:iA5D3C640F1243F44
GO

Sequence cautioni

Q3U3V8: The sequence DAA00368 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK154558 mRNA. Translation: BAE32677.1.
BC151014 mRNA. Translation: AAI51015.1.
BC151020 mRNA. Translation: AAI51021.1.
BK000542 mRNA. Translation: DAA00368.1. Different initiation.
CCDSiCCDS52321.1.
RefSeqiNP_001157730.1. NM_001164258.1.
XP_006508070.1. XM_006508007.2.
UniGeneiMm.440757.

Genome annotation databases

EnsembliENSMUST00000036155; ENSMUSP00000035929; ENSMUSG00000035211.
GeneIDi446101.
KEGGimmu:446101.
UCSCiuc009ime.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiXRRA1_MOUSE
AccessioniPrimary (citable) accession number: Q3U3V8
Secondary accession number(s): B2RX67, Q7M740
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 11, 2005
Last modified: May 10, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot