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Protein
Submitted name:

Cyclin-K

Gene

Ccnk

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCyclinUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-112382. Formation of RNA Pol II elongation complex.
R-MMU-2173796. SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription.
R-MMU-674695. RNA Polymerase II Pre-transcription Events.
R-MMU-6796648. TP53 Regulates Transcription of DNA Repair Genes.
R-MMU-6807505. RNA polymerase II transcribes snRNA genes.
R-MMU-75955. RNA Polymerase II Transcription Elongation.

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-KImported
Gene namesi
Name:CcnkImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1276106. Ccnk.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000021258.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3U3M5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 149CYCLINInterPro annotationAdd BLAST95
Domaini158 – 278Cyclin_CInterPro annotationAdd BLAST121
Domaini162 – 256CYCLINInterPro annotationAdd BLAST95

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0834. Eukaryota.
COG5333. LUCA.
GeneTreeiENSGT00760000119191.
HOGENOMiHOG000220828.
HOVERGENiHBG050836.
OMAiNSYMSGE.
OrthoDBiEOG091G0H4W.
TreeFamiTF101010.

Family and domain databases

CDDicd00043. CYCLIN. 2 hits.
Gene3Di1.10.472.10. 2 hits.
2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR013763. Cyclin-like.
IPR036915. Cyclin-like_sf.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
IPR015943. WD40/YVTN_repeat-like_dom_sf.
PfamiView protein in Pfam
PF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
SMARTiView protein in SMART
SM00385. CYCLIN. 2 hits.
SM01332. Cyclin_C. 1 hit.
SUPFAMiSSF47954. SSF47954. 2 hits.

Sequencei

Sequence statusi: Complete.

Q3U3M5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKENKENSSP SVTSANLDHT KPCWYWDKKD LAHTPSQLEG LDPATEARYR
60 70 80 90 100
REGARFIFDV GTRLGLHYDT LATGIIYFHR FYMFHSFKQF PRYVTGACCL
110 120 130 140 150
FLAGKVEETP KKCKDIIKTA RSLLNDVQFG QFGDDPKEEV MVLERILLQT
160 170 180 190 200
IKFDLQVEHP YQFLLKYAKQ LKGDKNKIQK LVQMAWTFVN DSLCTTLSLQ
210 220 230 240 250
WEPEIIAVAV MYLAGRLCKF EIQEWTSKPM YRRWWEQFVQ DVPVDVLEDI
260 270 280 290 300
CHQILDLYSQ GKQQMPHHTP HQLQQPPSLQ PTPQVPQGPQ SQPSQGSEAA
310 320 330 340 350
QPPQKDSQQS AQQQQQQAQQ PKKPSPQPSP PRQAKRAVVV SPKEENKATE
360 370 380 390 400
PPPPPKIPKL EATHPPLPPA HPPPDRKPPL APALGEAEAT GPVETSDLPK
410 420 430 440 450
VQIPPPAHPA PVHQPPPLPH RPPPPPPSSY MTGMSTTSSY MSGEGYQSLQ
460 470 480 490 500
SMMKTEGPSY GALPPAYGPP AHLTYHPHVY PPNPPPPPVP PPPASFPPPT
510 520 530 540 550
IPPPTPGYPP PPPTYNPNFP PPPPRLPPTH AVPPHPPPGL GLPPASYPPP
560 570 580
AVPPGGQPPV PPPIPPPGMP PVGGLGRAAW MR
Length:582
Mass (Da):64,350
Last modified:October 11, 2005 - v1
Checksum:i41462E8EB8EE7A61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152059 Genomic DNA. No translation available.
AK146711 mRNA. Translation: BAE27377.1.
AK154679 mRNA. Translation: BAE32760.1.
RefSeqiNP_033962.2. NM_009832.2.
XP_006515506.1. XM_006515443.3.
XP_006515507.1. XM_006515444.3.
XP_006515508.1. XM_006515445.2.
UniGeneiMm.474441.

Genome annotation databases

EnsembliENSMUST00000101055; ENSMUSP00000098616; ENSMUSG00000021258.
ENSMUST00000221167; ENSMUSP00000152784; ENSMUSG00000021258.
GeneIDi12454.
KEGGimmu:12454.
UCSCiuc011yrr.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ3U3M5_MOUSE
AccessioniPrimary (citable) accession number: Q3U3M5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: January 31, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported