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Protein
Submitted name:

2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

Gene

Bckdha

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-389661. Glyoxylate metabolism and glycine degradation.
R-MMU-70895. Branched-chain amino acid catabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrialImported
Submitted name:
Branched chain ketoacid dehydrogenase E1, alpha polypeptideImported
Gene namesi
Name:BckdhaImported
ORF Names:mCG_7651Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:107701. Bckdha.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000060376.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071292.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini107 – 406E1_dhInterPro annotationAdd BLAST300

Phylogenomic databases

eggNOGiKOG1182. Eukaryota.
COG1071. LUCA.
GeneTreeiENSGT00530000063174.
HOGENOMiHOG000281337.
HOVERGENiHBG002459.
KOiK00166.
OMAiKKDACAI.
OrthoDBiEOG091G073F.
TreeFamiTF300863.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3U3J1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIVMSAAKI WRPSRGLRQA ALLLLGRSGV RGLARSHPSR QQQQQFPSLD
60 70 80 90 100
DKPQFPGASA EFVDKLEFIQ PNVISGIPIY RVMDRQGQII NPSEDPHLPQ
110 120 130 140 150
EEVLKFYRSM TLLNTMDRIL YESQRQGRIS FYMTNYGEEG THVGSAAALE
160 170 180 190 200
RTDLVFGQYR EAGVLMYRDY PLELFMSQCY GNVNDPGKGR QMPVHYGCKE
210 220 230 240 250
RHFVTISSPL ATQIPQAVGA AYAAKRANAN RIVICYFGEG AASEGDAHAG
260 270 280 290 300
FNFAATLECP IIFFCRNNGY AISTPTSEQY RGDGIAARGP GYGIMSIRVD
310 320 330 340 350
GNDVFAVYNA TKEARRRAVA ENQPFLIEAM TYRIGHHSTS DDSSAYRSVD
360 370 380 390 400
EVNYWDKQDH PISRLRQYLL NQGWWDEEQE KAWRKQSRKK VMEAFEQAER
410 420 430 440
KLKPNPSLLF SDVYQEMPAQ LRRQQESLAR HLQTYGEHYP LDHFDK
Length:446
Mass (Da):50,773
Last modified:October 11, 2005 - v1
Checksum:i110D5F3FA8A3108D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC162614 Genomic DNA. No translation available.
AK154734 mRNA. Translation: BAE32795.1.
CH466593 Genomic DNA. Translation: EDL24248.1.
RefSeqiNP_031559.3. NM_007533.5.
UniGeneiMm.25848.

Genome annotation databases

EnsembliENSMUST00000071329; ENSMUSP00000071292; ENSMUSG00000060376.
GeneIDi12039.
KEGGimmu:12039.
UCSCiuc009fth.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC162614 Genomic DNA. No translation available.
AK154734 mRNA. Translation: BAE32795.1.
CH466593 Genomic DNA. Translation: EDL24248.1.
RefSeqiNP_031559.3. NM_007533.5.
UniGeneiMm.25848.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071292.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000071329; ENSMUSP00000071292; ENSMUSG00000060376.
GeneIDi12039.
KEGGimmu:12039.
UCSCiuc009fth.2. mouse.

Organism-specific databases

CTDi593.
MGIiMGI:107701. Bckdha.

Phylogenomic databases

eggNOGiKOG1182. Eukaryota.
COG1071. LUCA.
GeneTreeiENSGT00530000063174.
HOGENOMiHOG000281337.
HOVERGENiHBG002459.
KOiK00166.
OMAiKKDACAI.
OrthoDBiEOG091G073F.
TreeFamiTF300863.

Enzyme and pathway databases

ReactomeiR-MMU-389661. Glyoxylate metabolism and glycine degradation.
R-MMU-70895. Branched-chain amino acid catabolism.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000060376.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3U3J1_MOUSE
AccessioniPrimary (citable) accession number: Q3U3J1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 2, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.