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Q3U2P8

- Q3U2P8_MOUSE

UniProt

Q3U2P8 - Q3U2P8_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Mapkapk2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: Ensembl

GO - Biological processi

  1. 3'-UTR-mediated mRNA stabilization Source: Ensembl
  2. cellular response to vascular endothelial growth factor stimulus Source: Ensembl
  3. G2 DNA damage checkpoint Source: Ensembl
  4. inner ear development Source: MGI
  5. mRNA stabilization Source: MGI
  6. peptidyl-serine phosphorylation Source: Ensembl
  7. regulation of tumor necrosis factor production Source: Ensembl
  8. response to cytokine Source: Ensembl
  9. vascular endothelial growth factor receptor signaling pathway Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Mapkapk2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:109298. Mapkapk2.

Subcellular locationi

GO - Cellular componenti

  1. centrosome Source: Ensembl
  2. cytoplasm Source: MGI
  3. nucleus Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ3U2P8.

Expressioni

Gene expression databases

BgeeiQ3U2P8.
ExpressionAtlasiQ3U2P8. baseline and differential.
GenevestigatoriQ3U2P8.

Structurei

3D structure databases

ProteinModelPortaliQ3U2P8.
SMRiQ3U2P8. Positions 37-376.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119016.
HOVERGENiHBG106948.
KOiK04443.
OMAiLQMLQDC.
PhylomeDBiQ3U2P8.

Family and domain databases

Gene3Di4.10.1170.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR027442. MAPKAPK_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3U2P8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLSGSPGQTP PAPFPSPPPP APAQPPPPFP QFHVKSGLQI RKNAITDDYK
60 70 80 90 100
VTSQVLGLGI NGKVLRIFDK RTQQKFALKM LQDCPKARRE VELHWRASQC
110 120 130 140 150
PHIVHIVDVY ENLYAGRKCL LIVMECLDGG ELFSRIQDRG DQAFTEREAS
160 170 180 190 200
EIMKSIGEAI QYLHSINIAH RDVKPENLLY TSKRPNAILK LTDFGFAKET
210 220 230 240 250
TSHNSLTTPC YTPYYVAPEV LGPEKYDKSC DMWSLGVIMY ILLCGYPPFY
260 270 280 290 300
SNHGLAISPG MKTRIRMGQY EFPNPEWSEV SEEVKMLIRN LLKTEPTQRM
310 320 330 340 350
TITEFMNHPW IMQSTKVPQT PLHTSRVLKE DKERWEDVKE EMTSALATMR
360 370 380
VDYEQIKIKK IEDASNPLLL KRRKKARAVE DAALAH
Length:386
Mass (Da):44,050
Last modified:October 11, 2005 - v1
Checksum:iED7827641A826BF3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK155171 mRNA. Translation: BAE33092.1.
RefSeqiNP_032577.1. NM_008551.1.
UniGeneiMm.221235.
Mm.490983.

Genome annotation databases

GeneIDi17164.
KEGGimmu:17164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK155171 mRNA. Translation: BAE33092.1 .
RefSeqi NP_032577.1. NM_008551.1.
UniGenei Mm.221235.
Mm.490983.

3D structure databases

ProteinModelPortali Q3U2P8.
SMRi Q3U2P8. Positions 37-376.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q3U2P8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 17164.
KEGGi mmu:17164.

Organism-specific databases

CTDi 9261.
MGIi MGI:109298. Mapkapk2.

Phylogenomic databases

GeneTreei ENSGT00760000119016.
HOVERGENi HBG106948.
KOi K04443.
OMAi LQMLQDC.
PhylomeDBi Q3U2P8.

Miscellaneous databases

ChiTaRSi MAPKAPK2. mouse.
NextBioi 291442.
SOURCEi Search...

Gene expression databases

Bgeei Q3U2P8.
ExpressionAtlasi Q3U2P8. baseline and differential.
Genevestigatori Q3U2P8.

Family and domain databases

Gene3Di 4.10.1170.10. 1 hit.
InterProi IPR011009. Kinase-like_dom.
IPR027442. MAPKAPK_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.

Entry informationi

Entry nameiQ3U2P8_MOUSE
AccessioniPrimary (citable) accession number: Q3U2P8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)