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Q3U2P8

- Q3U2P8_MOUSE

UniProt

Q3U2P8 - Q3U2P8_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Mapkapk2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: Ensembl

    GO - Biological processi

    1. 3'-UTR-mediated mRNA stabilization Source: Ensembl
    2. cellular response to vascular endothelial growth factor stimulus Source: Ensembl
    3. G2 DNA damage checkpoint Source: Ensembl
    4. inner ear development Source: MGI
    5. mRNA stabilization Source: MGI
    6. peptidyl-serine phosphorylation Source: Ensembl
    7. regulation of tumor necrosis factor production Source: Ensembl
    8. response to cytokine Source: Ensembl
    9. vascular endothelial growth factor receptor signaling pathway Source: Ensembl

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Mapkapk2Imported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:109298. Mapkapk2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. nucleus Source: MGI

    PTM / Processingi

    Proteomic databases

    PRIDEiQ3U2P8.

    Expressioni

    Gene expression databases

    ArrayExpressiQ3U2P8.
    BgeeiQ3U2P8.
    GenevestigatoriQ3U2P8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3U2P8.
    SMRiQ3U2P8. Positions 37-376.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00730000110339.
    HOVERGENiHBG106948.
    InParanoidiQ3U2P8.
    KOiK04443.
    OMAiLQMLQDC.
    PhylomeDBiQ3U2P8.

    Family and domain databases

    Gene3Di4.10.1170.10. 1 hit.
    InterProiIPR011009. Kinase-like_dom.
    IPR027442. MAPKAPK_C.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3U2P8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLSGSPGQTP PAPFPSPPPP APAQPPPPFP QFHVKSGLQI RKNAITDDYK    50
    VTSQVLGLGI NGKVLRIFDK RTQQKFALKM LQDCPKARRE VELHWRASQC 100
    PHIVHIVDVY ENLYAGRKCL LIVMECLDGG ELFSRIQDRG DQAFTEREAS 150
    EIMKSIGEAI QYLHSINIAH RDVKPENLLY TSKRPNAILK LTDFGFAKET 200
    TSHNSLTTPC YTPYYVAPEV LGPEKYDKSC DMWSLGVIMY ILLCGYPPFY 250
    SNHGLAISPG MKTRIRMGQY EFPNPEWSEV SEEVKMLIRN LLKTEPTQRM 300
    TITEFMNHPW IMQSTKVPQT PLHTSRVLKE DKERWEDVKE EMTSALATMR 350
    VDYEQIKIKK IEDASNPLLL KRRKKARAVE DAALAH 386
    Length:386
    Mass (Da):44,050
    Last modified:October 11, 2005 - v1
    Checksum:iED7827641A826BF3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK155171 mRNA. Translation: BAE33092.1.
    RefSeqiNP_032577.1. NM_008551.1.
    UniGeneiMm.221235.
    Mm.490983.

    Genome annotation databases

    GeneIDi17164.
    KEGGimmu:17164.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK155171 mRNA. Translation: BAE33092.1 .
    RefSeqi NP_032577.1. NM_008551.1.
    UniGenei Mm.221235.
    Mm.490983.

    3D structure databases

    ProteinModelPortali Q3U2P8.
    SMRi Q3U2P8. Positions 37-376.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q3U2P8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 17164.
    KEGGi mmu:17164.

    Organism-specific databases

    CTDi 9261.
    MGIi MGI:109298. Mapkapk2.

    Phylogenomic databases

    GeneTreei ENSGT00730000110339.
    HOVERGENi HBG106948.
    InParanoidi Q3U2P8.
    KOi K04443.
    OMAi LQMLQDC.
    PhylomeDBi Q3U2P8.

    Miscellaneous databases

    ChiTaRSi MAPKAPK2. mouse.
    NextBioi 291442.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3U2P8.
    Bgeei Q3U2P8.
    Genevestigatori Q3U2P8.

    Family and domain databases

    Gene3Di 4.10.1170.10. 1 hit.
    InterProi IPR011009. Kinase-like_dom.
    IPR027442. MAPKAPK_C.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NODImported.

    Entry informationi

    Entry nameiQ3U2P8_MOUSE
    AccessioniPrimary (citable) accession number: Q3U2P8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)