Rras

Functionⁱ

GO - Molecular functionⁱ

GDP binding Source: Ensembl
GTPase activity Source: Ensembl
GTP binding Source: UniProtKB-KW
protein complex binding Source: Ensembl

Complete GO annotation...

GO - Biological processⁱ

face morphogenesis Source: Ensembl
leukocyte differentiation Source: Ensembl
negative regulation of cell migration Source: Ensembl
positive regulation of angiogenesis Source: Ensembl
regulation of ERK1 and ERK2 cascade Source: Ensembl
regulation of protein kinase B signaling Source: Ensembl
signal transduction Source: InterPro

Complete GO annotation...

Keywordsⁱ

Ligand	GTP-bindingSAAS annotation, Nucleotide-binding

Ligand

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Harvey rat sarcoma oncogene, subgroup RImported Submitted name: Putative uncharacterized proteinImported
Gene namesⁱ	Name:RrasImported
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:98179. Rras.

Subcellular locationⁱ

GO - Cellular componentⁱ

extracellular exosome Source: Ensembl
focal adhesion Source: Ensembl
membrane Source: InterPro

Complete GO annotation...

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q3U1N3.

MaxQBⁱ

Q3U1N3.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000038387.
ExpressionAtlasⁱ	Q3U1N3. baseline and differential.

Interactionⁱ

GO - Molecular functionⁱ

protein complex binding Source: Ensembl

Complete GO annotation...

Structureⁱ

3D structure databases

SMRⁱ	Q3U1N3.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	KOG0395. Eukaryota. COG1100. LUCA.
HOVERGENⁱ	HBG009351.
KEGG Orthology (KO) More...KOⁱ	K07829.
OMAⁱ	RSEASTF.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0UAU.

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR001806. Small_GTPase. IPR020849. Small_GTPase_Ras.
PANTHERⁱ	PTHR24070. PTHR24070. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00071. Ras. 1 hit.
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
TIGRFAMsⁱ	TIGR00231. small_GTP. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51421. RAS. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q3U1N3-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSSGAASGTG RGRPRGGGPG PRDPPPGETH KLVVVGGGGV GKSALTIQFI 
        60         70         80         90        100
QSYFVSDYDP TIEDSYTKIC TVDGIPARLD ILDTAGQEEF GAMREQYMRA 
       110        120        130        140        150
GNGFLLVFAI NDRQSFNEVG KLFTQILRVK DRDDFPIVLV GNKADLENQR 
       160        170        180        190        200
QVLRSEASSF SASHHMTYFE ASAKLRLNVD EAFEQLVRAV RKYQEQELPP 
       210 
SPPSAPRKKD GGCPCVLL

Length:218

Mass (Da):23,764

Last modified:October 11, 2005 - v1

Checksum:ⁱC1D32CE7904322E5

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC110562 mRNA. Translation: AAI10563.1. BC110563 mRNA. Translation: AAI10564.1. BC145932 mRNA. Translation: AAI45933.1. BC145934 mRNA. Translation: AAI45935.1. AK155855 mRNA. Translation: BAE33462.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_033127.1. NM_009101.2.
UniGeneⁱ	Mm.389894.

Genome annotation databases

GeneIDⁱ	20130.
KEGGⁱ	mmu:20130.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC110562 mRNA. Translation: AAI10563.1. BC110563 mRNA. Translation: AAI10564.1. BC145932 mRNA. Translation: AAI45933.1. BC145934 mRNA. Translation: AAI45935.1. AK155855 mRNA. Translation: BAE33462.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_033127.1. NM_009101.2.
UniGeneⁱ	Mm.389894.

3D structure databases

SMRⁱ	Q3U1N3.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q3U1N3.

MaxQBⁱ

Q3U1N3.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	20130.
KEGGⁱ	mmu:20130.

Organism-specific databases

CTDⁱ	6237.
MGIⁱ	MGI:98179. Rras.

Phylogenomic databases

eggNOGⁱ	KOG0395. Eukaryota. COG1100. LUCA.
HOVERGENⁱ	HBG009351.
KEGG Orthology (KO) More...KOⁱ	K07829.
OMAⁱ	RSEASTF.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0UAU.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000038387.
ExpressionAtlasⁱ	Q3U1N3. baseline and differential.

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR001806. Small_GTPase. IPR020849. Small_GTPase_Ras.
PANTHERⁱ	PTHR24070. PTHR24070. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00071. Ras. 1 hit.
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
TIGRFAMsⁱ	TIGR00231. small_GTP. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51421. RAS. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q3U1N3_MOUSE
Accessionⁱ	Q3U1N3Primary (citable) accession number: Q3U1N3
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 11, 2005
	Last sequence update:	October 11, 2005
	Last modified:	July 5, 2017
	This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q3U1N3 (Q3U1N3_MOUSE)

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Harvey rat sarcoma oncogene, subgroup R

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q3U1N3 (Q3U1N3_MOUSE)

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Harvey rat sarcoma oncogene, subgroup R

Rras

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ