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Protein

C-X-C motif chemokine

Gene

Cxcl2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-X-C motif chemokineUniRule annotation
Gene namesi
Name:Cxcl2Imported
ORF Names:mCG_1710Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1340094 Cxcl2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27UniRule annotationAdd BLAST27
ChainiPRO_501420582728 – 100C-X-C motif chemokineUniRule annotationAdd BLAST73

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000058427
ExpressionAtlasiQ3U1J5 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3U1J5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 93SCYInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the intercrine alpha (chemokine CxC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J3WE Eukaryota
ENOG410ZT1C LUCA
HOVERGENiHBG107789
KOiK05505
OMAiNGKKACL
OrthoDBiEOG091G14TE

Family and domain databases

CDDicd00273 Chemokine_CXC, 1 hit
InterProiView protein in InterPro
IPR001089 Chemokine_CXC
IPR018048 Chemokine_CXC_CS
IPR001811 Chemokine_IL8-like_dom
IPR033899 CXC_Chemokine_domain
IPR036048 Interleukin_8-like_sf
PANTHERiPTHR10179 PTHR10179, 1 hit
PfamiView protein in Pfam
PF00048 IL8, 1 hit
PRINTSiPR00437 SMALLCYTKCXC
SMARTiView protein in SMART
SM00199 SCY, 1 hit
SUPFAMiSSF54117 SSF54117, 1 hit
PROSITEiView protein in PROSITE
PS00471 SMALL_CYTOKINES_CXC, 1 hit

Sequencei

Sequence statusi: Complete.

Q3U1J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPPTCRLLS AALVLLLLLA TNHQATGAVV ASELRCQCLK TLPRVDFKNI
60 70 80 90 100
QSLSVTPPGP HCAQTEVIAT LKGGQKVCLD PEAPLVQKII QKILNKGKAN
Length:100
Mass (Da):10,621
Last modified:October 11, 2005 - v1
Checksum:iB9EF0A3218EE92B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC119511 mRNA Translation: AAI19512.1
BC119512 mRNA Translation: AAI19513.1
AK137628 mRNA Translation: BAE23436.1
AK155916 mRNA Translation: BAE33502.1
AK157079 mRNA Translation: BAE33956.1
CH466617 Genomic DNA Translation: EDL05300.1
RefSeqiNP_033166.1, NM_009140.2
UniGeneiMm.4979

Genome annotation databases

GeneIDi20310
KEGGimmu:20310

Similar proteinsi

Entry informationi

Entry nameiQ3U1J5_MOUSE
AccessioniPrimary (citable) accession number: Q3U1J5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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