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Protein
Submitted name:

Interferon regulatory factor 5

Gene

Irf5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 5Imported
Gene namesi
Name:Irf5Imported
ORF Names:mCG_9128Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1350924. Irf5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000029771.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000004392.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 122109IRF tryptophan pentad repeat DNA-bindingInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IFCV. Eukaryota.
ENOG410XRXT. LUCA.
GeneTreeiENSGT00760000119093.
HOVERGENiHBG105715.
KOiK09446.
OMAiYDGPRDM.
OrthoDBiEOG091G067P.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.200.10. 1 hit.
InterProiIPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR019471. Interferon_reg_factor-3.
IPR029838. IRF5.
IPR017855. SMAD_dom-like.
IPR008984. SMAD_FHA_domain.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR11949:SF10. PTHR11949:SF10. 1 hit.
PfamiPF00605. IRF. 1 hit.
PF10401. IRF-3. 1 hit.
[Graphical view]
PRINTSiPR00267. INTFRNREGFCT.
SMARTiSM00348. IRF. 1 hit.
SM01243. IRF-3. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF49879. SSF49879. 1 hit.
PROSITEiPS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3U169-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNHSAPGIPP PPRRVRLKPW LVAQVNSCQY PGLQWVNGEK KLFYIPWRHA
60 70 80 90 100
TRHGPSQDGD NTIFKAWAKE TGKYTEGVDE ADPAKWKANL RCALNKSRDF
110 120 130 140 150
QLFYDGPRDM PPQPYKIYEV CSNGPAPTES QPTDDYVLGE EEEEEEEELQ
160 170 180 190 200
RMLPGLSITE PALPGPPNAP YSLPKEDTKW PPALQPPVGL GPPVPDPNLL
210 220 230 240 250
APPSGNPAGF RQLLPEVLEP GPLASSQPPT EPLLPDLLIS PHMLPLTDLE
260 270 280 290 300
IKFQYRGRAP RTLTISNPQG CRLFYSQLEA TQEQVELFGP VTLEQVRFPS
310 320 330 340 350
PEDIPSDKQR FYTNQLLDVL DRGLILQLQG QDLYAIRLCQ CKVFWSGPCA
360 370 380 390 400
LAHGSCPNPI QREVKTKLFS LEQFLNELIL FQKGQTNTPP PFEIFFCFGE
410 420 430 440 450
EWPDVKPREK KLITVQVVPV AARLLLEMFS GELSWSADSI RLQISNPDLK
460 470 480 490
DHMVEQFKEL HHLWQSQQQL QPMVQAPPVA GLDASQGPWP MHPVGMQ
Length:497
Mass (Da):56,005
Last modified:October 11, 2005 - v1
Checksum:iD8BD54DB946E354F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK151019 mRNA. Translation: BAE30037.1.
AK156220 mRNA. Translation: BAE33631.1.
CH466533 Genomic DNA. Translation: EDL13770.1.
RefSeqiNP_036187.1. NM_012057.4.
XP_006505160.1. XM_006505097.1.
UniGeneiMm.6479.

Genome annotation databases

GeneIDi27056.
KEGGimmu:27056.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK151019 mRNA. Translation: BAE30037.1.
AK156220 mRNA. Translation: BAE33631.1.
CH466533 Genomic DNA. Translation: EDL13770.1.
RefSeqiNP_036187.1. NM_012057.4.
XP_006505160.1. XM_006505097.1.
UniGeneiMm.6479.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000004392.

Protocols and materials databases

DNASUi27056.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi27056.
KEGGimmu:27056.

Organism-specific databases

CTDi3663.
MGIiMGI:1350924. Irf5.

Phylogenomic databases

eggNOGiENOG410IFCV. Eukaryota.
ENOG410XRXT. LUCA.
GeneTreeiENSGT00760000119093.
HOVERGENiHBG105715.
KOiK09446.
OMAiYDGPRDM.
OrthoDBiEOG091G067P.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029771.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.200.10. 1 hit.
InterProiIPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR019471. Interferon_reg_factor-3.
IPR029838. IRF5.
IPR017855. SMAD_dom-like.
IPR008984. SMAD_FHA_domain.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR11949:SF10. PTHR11949:SF10. 1 hit.
PfamiPF00605. IRF. 1 hit.
PF10401. IRF-3. 1 hit.
[Graphical view]
PRINTSiPR00267. INTFRNREGFCT.
SMARTiSM00348. IRF. 1 hit.
SM01243. IRF-3. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF49879. SSF49879. 1 hit.
PROSITEiPS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3U169_MOUSE
AccessioniPrimary (citable) accession number: Q3U169
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.