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Protein
Submitted name:

Interleukin 1 alpha

Gene

Il1a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation, MitogenUniRule annotation, PyrogenUniRule annotation
Biological processInflammatory response

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 1 alphaImported
Submitted name:
Interleukin 1 alpha, isoform CRA_bImported
Gene namesi
Name:Il1aImported
ORF Names:mCG_20997Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96542. Il1a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000027399.

Interactioni

Subunit structurei

Monomer.UniRule annotation

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 110IL1_propepInterPro annotationAdd BLAST110

Sequence similaritiesi

Belongs to the IL-1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410JAAI. Eukaryota.
ENOG411151X. LUCA.
HOVERGENiHBG002432.
KOiK04383.
OMAiNQKSFYD.
OrthoDBiEOG091G0MAP.

Family and domain databases

InterProiView protein in InterPro
IPR003295. IL-1_alpha.
IPR020877. IL-1_CS.
IPR000975. IL-1_fam.
IPR003502. IL-1_propep.
IPR008996. IL1/FGF.
PANTHERiPTHR10078:SF67. PTHR10078:SF67. 1 hit.
PfamiView protein in Pfam
PF00340. IL1. 1 hit.
PF02394. IL1_propep. 1 hit.
PRINTSiPR00264. INTERLEUKIN1.
PR01358. INTRLEUKIN1A.
SUPFAMiSSF50353. SSF50353. 1 hit.
PROSITEiView protein in PROSITE
PS00253. INTERLEUKIN_1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3U0Y6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVPDLFED LKNCYSENED YSSAIDHLSL NQKSFYDASY GSLHETCTDQ
60 70 80 90 100
FVSLRTSETS KMSNFTFKES RVTVSATSSN GKILKKRRLS FSETFTEDDL
110 120 130 140 150
QSITHDLEET IQPRSAPYTY QSDLRYKLMK LVRQKFVMND SLNQTIYQDV
160 170 180 190 200
DKHYLSTTWL NDLQQEVKFD MYAYSSGGDD SKYPVTLKIS DSQLFVSAQG
210 220 230 240 250
EDQPVLLKEL PETPKLITGS ETDLIFFWKS INSKNYFTSA AYPELFIATK
260 270
EQSRVHLARG LPSMTDFQIS
Length:270
Mass (Da):31,023
Last modified:October 11, 2005 - v1
Checksum:i7F60AC4F330D5B11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY902318 Genomic DNA. Translation: AAX90603.1.
AK156449 mRNA. Translation: BAE33715.1.
CH466519 Genomic DNA. Translation: EDL28237.1.
RefSeqiNP_034684.2. NM_010554.4.
XP_006498856.1. XM_006498793.3.
UniGeneiMm.15534.

Genome annotation databases

GeneIDi16175.
KEGGimmu:16175.

Similar proteinsi

Entry informationi

Entry nameiQ3U0Y6_MOUSE
AccessioniPrimary (citable) accession number: Q3U0Y6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: August 30, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)