Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Protein Zfp217

Gene

Zfp217

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: MGI
  3. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Source: MGI
  4. transcription regulatory region DNA binding Source: MGI

GO - Biological processi

  1. cell aging Source: MGI
  2. negative regulation of transcription, DNA-templated Source: MGI
  3. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  4. regulation of transcription, DNA-templated Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Zfp217Imported
Submitted name:
Zinc finger protein 217Imported
Gene namesi
Name:Zfp217Imported
ORF Names:mCG_6549Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:2685408. Zfp217.

Subcellular locationi

GO - Cellular componenti

  1. histone deacetylase complex Source: MGI
  2. nucleoplasm Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiQ3U0X6.
PRIDEiQ3U0X6.

PTM databases

PhosphoSiteiQ3U0X6.

Expressioni

Gene expression databases

BgeeiQ3U0X6.
ExpressionAtlasiQ3U0X6. baseline and differential.
GenevestigatoriQ3U0X6.

Interactioni

Protein-protein interaction databases

IntActiQ3U0X6. 1 interaction.
STRINGi10090.ENSMUSP00000067334.

Structurei

3D structure databases

ProteinModelPortaliQ3U0X6.
SMRiQ3U0X6. Positions 52-85, 138-177, 198-236, 375-411, 477-530.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG319981.
GeneTreeiENSGT00530000063100.
HOGENOMiHOG000276541.
HOVERGENiHBG061769.
InParanoidiQ3U0X6.
OMAiNEVVQEH.
OrthoDBiEOG7CNZFG.
PhylomeDBiQ3U0X6.
TreeFamiTF332241.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 8 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3U0X6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTQSLLVYM DGPEVLSSSL GSQMEVDDAV PIKGPVAVPF RAAQEKSMAV
60 70 80 90 100
AEGHMPLDCM FCSQVFSQAE DLSQHVLLQH RPTLCEPAVL RVEAEYLSPL
110 120 130 140 150
DKALEPTEPA LEKSGEDPEE LSCDVCGQTF PVAFDVESHM KKHKDSFTYG
160 170 180 190 200
CSMCGRRFKE PWFLKNHMRT HNGKSGTRSK LQQGMESPVT INEVVQPHAP
210 220 230 240 250
GSISTPYKIC MVCGFLFPNK QSLIEHSKVH AKETVPSASN VAPDDHREEP
260 270 280 290 300
TSPREELLQF LNLRPRSTAG STVKPMTCIP QLDPFTTYQA WQLATKGKVA
310 320 330 340 350
VAQEEVKESG QEGSTDNDDS CSEKEELGEI WVGGKAEGSG KSKTSKSSCP
360 370 380 390 400
GLSQDKEKPR HANSEVPSGD SDPKLSSSKE KPTHCSECSK AFRTYHQLVL
410 420 430 440 450
HSRVHRKDRR TDALSPTMAV DARQPGTCSP DLSTTLEDSG AGDREGGSED
460 470 480 490 500
GSEDGLPDGL HLDKNDDGGK AKPLPSSREC SYCGKFFRSN YYLNIHLRTH
510 520 530 540 550
TGEKPYKCEF CEYAAAQKTS LRYHLERHHK DKQPVDAAAE SKSEGRSQEP
560 570 580 590 600
QDALLTAADS AQTKNLKRFL DGAKDVKGSP PAKQLKEMPS VFQSVLSPAH
610 620 630 640 650
SNDTQDFHKH AADSAEKARK SPAPTYLDMQ RKKAGEPQAS SPVCRLEGVG
660 670 680 690 700
SLAREAGHRE KMDQDADYRH KPGADCQDRP LNLSLGPLHA CPAISLSKCL
710 720 730 740 750
IPSIACPFCT FKTFYPEVLM MHQRLEHRYN PDPHKNGSSK SVLRNRRTGC
760 770 780 790 800
PPALLGKDVP PLSGLHKPKA KTAFSPHSKS LHSEKARQGA SGPSKAPQTS
810 820 830 840 850
GPDNSTLAPS NLKSHRSQPN AGGTSATRQQ QSELFPKGGV PAAMDKVKRP
860 870 880 890 900
EPKLKSLPAS PSQSPLSSNN SNGSVEYPVK VDGPWAQQGR DYYCHRNSGS
910 920 930 940 950
AAAEYSEPHP KRLKSSAVSL DTEHAGTNGR RGFELPKYHV VRSITSLLPP
960 970 980 990 1000
ECVRPPPVLP HKARFLSPGE VESPSVLAVQ KPYSASGPLY TCGPVGHAGG
1010 1020 1030 1040
SPALEGKRPV SHQHLSNSML QKRSYENFIG NTHYRPNDKK P
Length:1,041
Mass (Da):113,600
Last modified:October 10, 2005 - v1
Checksum:i610BB8BCC936C50D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844576 Genomic DNA. No translation available.
BC116329 mRNA. Translation: AAI16330.1.
BC116330 mRNA. Translation: AAI16331.1.
AK156475 mRNA. Translation: BAE33725.1.
CH466551 Genomic DNA. Translation: EDL06576.1.
RefSeqiNP_001028471.1. NM_001033299.3.
NP_001153155.1. NM_001159683.1.
XP_006499490.1. XM_006499427.2.
XP_006499491.1. XM_006499428.1.
XP_006499492.1. XM_006499429.2.
XP_006499493.1. XM_006499430.1.
XP_006499494.1. XM_006499431.2.
XP_006499495.1. XM_006499432.2.
XP_006499496.1. XM_006499433.2.
UniGeneiMm.22858.

Genome annotation databases

EnsembliENSMUST00000063710; ENSMUSP00000067334; ENSMUSG00000052056.
ENSMUST00000109155; ENSMUSP00000104783; ENSMUSG00000052056.
GeneIDi228913.
KEGGimmu:228913.
UCSCiuc008obu.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844576 Genomic DNA. No translation available.
BC116329 mRNA. Translation: AAI16330.1.
BC116330 mRNA. Translation: AAI16331.1.
AK156475 mRNA. Translation: BAE33725.1.
CH466551 Genomic DNA. Translation: EDL06576.1.
RefSeqiNP_001028471.1. NM_001033299.3.
NP_001153155.1. NM_001159683.1.
XP_006499490.1. XM_006499427.2.
XP_006499491.1. XM_006499428.1.
XP_006499492.1. XM_006499429.2.
XP_006499493.1. XM_006499430.1.
XP_006499494.1. XM_006499431.2.
XP_006499495.1. XM_006499432.2.
XP_006499496.1. XM_006499433.2.
UniGeneiMm.22858.

3D structure databases

ProteinModelPortaliQ3U0X6.
SMRiQ3U0X6. Positions 52-85, 138-177, 198-236, 375-411, 477-530.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ3U0X6. 1 interaction.
STRINGi10090.ENSMUSP00000067334.

PTM databases

PhosphoSiteiQ3U0X6.

Proteomic databases

MaxQBiQ3U0X6.
PRIDEiQ3U0X6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000063710; ENSMUSP00000067334; ENSMUSG00000052056.
ENSMUST00000109155; ENSMUSP00000104783; ENSMUSG00000052056.
GeneIDi228913.
KEGGimmu:228913.
UCSCiuc008obu.2. mouse.

Organism-specific databases

CTDi228913.
MGIiMGI:2685408. Zfp217.

Phylogenomic databases

eggNOGiNOG319981.
GeneTreeiENSGT00530000063100.
HOGENOMiHOG000276541.
HOVERGENiHBG061769.
InParanoidiQ3U0X6.
OMAiNEVVQEH.
OrthoDBiEOG7CNZFG.
PhylomeDBiQ3U0X6.
TreeFamiTF332241.

Miscellaneous databases

NextBioi379250.
PROiQ3U0X6.
SOURCEiSearch...

Gene expression databases

BgeeiQ3U0X6.
ExpressionAtlasiQ3U0X6. baseline and differential.
GenevestigatoriQ3U0X6.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 8 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2000)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  6. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  9. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2004)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  10. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  11. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  12. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  13. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3U0X6_MOUSE
AccessioniPrimary (citable) accession number: Q3U0X6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 10, 2005
Last sequence update: October 10, 2005
Last modified: March 31, 2015
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.