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Protein

Methyltransferase-like protein 4

Gene

Mettl4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable methyltransferase.By similarity

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Methyltransferase-like protein 4 (EC:2.1.1.-)
Gene namesi
Name:Mettl4
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1924031 Mettl4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002512261 – 471Methyltransferase-like protein 4Add BLAST471

Proteomic databases

PaxDbiQ3U034
PRIDEiQ3U034

PTM databases

iPTMnetiQ3U034
PhosphoSitePlusiQ3U034

Expressioni

Gene expression databases

BgeeiENSMUSG00000055660
CleanExiMM_METTL4
GenevisibleiQ3U034 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000127142

Structurei

3D structure databases

ProteinModelPortaliQ3U034
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MT-A70-like family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2356 Eukaryota
ENOG410Y4SI LUCA
GeneTreeiENSGT00390000016237
HOGENOMiHOG000113569
HOVERGENiHBG078120
InParanoidiQ3U034
OMAiLSDISCM
OrthoDBiEOG091G0FJ4
PhylomeDBiQ3U034
TreeFamiTF314410

Family and domain databases

InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR007757 MT-A70-like
PfamiView protein in Pfam
PF05063 MT-A70, 1 hit
PROSITEiView protein in PROSITE
PS51143 MT_A70, 1 hit
PS00092 N6_MTASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q3U034-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVVHHLPPG WLLDHLSFIN KVNYQLCQHQ ESFCSKNNPT SSVYMDSLQL
60 70 80 90 100
DPGSPFGAPA MCFAPDFTTV SGNDDEGSCE VITEKYVFRS ELFNVTKPYI
110 120 130 140 150
VPAVHKERQQ SNKNENLVTD YKQEVSVSVG KKRKRCIAFN QGELDAMEYH
160 170 180 190 200
TKIRELILDG SSKLIQEGLR SGFLYPLVEK QDGSSGCITL PLDACNLSEL
210 220 230 240 250
CEMAKHLPSL NEMELQTLQL MGDDVSVIEL DLSSQIIENN SSFSKMITLM
260 270 280 290 300
GQKYLLPPQS SFLLSDISCM QPLLNCGKTF DAIVIDPPWE NKSVKRSNRY
310 320 330 340 350
SSLSPQQIKR MPIPKLAAAD CLIVTWVTNR QKHLCFVKEE LYPSWSVEVV
360 370 380 390 400
AEWYWVKITN SGEFVFPLDS PHKKPYECLV LGRVKEKTPL ALRNPDVRIP
410 420 430 440 450
PVPDQKLIVS VPCVLHSHKP PLTEVLRDYI KPGGQCLELF ARNLQPGWMS
460 470
WGNEVLKFQH MDYFIALESG C
Length:471
Mass (Da):53,306
Last modified:October 11, 2005 - v1
Checksum:i66C93ADF8FC0A43F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK157268 mRNA Translation: BAE34021.1
CCDSiCCDS29030.1
RefSeqiNP_795891.2, NM_176917.4
XP_006525168.1, XM_006525105.3
XP_006525169.1, XM_006525106.3
UniGeneiMm.139146
Mm.458562
Mm.486648

Genome annotation databases

EnsembliENSMUST00000171284; ENSMUSP00000127142; ENSMUSG00000055660
GeneIDi76781
KEGGimmu:76781
UCSCiuc008dwk.1 mouse

Similar proteinsi

Entry informationi

Entry nameiMETL4_MOUSE
AccessioniPrimary (citable) accession number: Q3U034
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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