Q3TZ44 (Q3TZ44_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aldose 1-epimerase PIRNR PIRNR005096
EC=5.1.3.3 PIRNR PIRNR005096

Alternative name(s):
Galactose mutarotase PIRNR PIRNR005096

Gene names

Name:

Galm MGI 2442420

Organism

Mus musculus (Mouse) EMBL BAE34366.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity. PIRNR PIRNR005096
Catalytic activity	Alpha-D-glucose = beta-D-glucose. PIRNR PIRNR005096
Pathway	Carbohydrate metabolism; hexose metabolism. PIRNR PIRNR005096
Subunit structure	Monomer By similarity. PIRNR PIRNR005096
Sequence similarities	Belongs to the aldose epimerase family. PIRNR PIRNR005096

Ontologies

Keywords
Biological process	Carbohydrate metabolism PIRNR PIRNR005096
Molecular function	Isomerase PIRNR PIRNR005096
Gene Ontology (GO)
Biological_process	hexose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3TZ44 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: EDED3F9A4CBF55C6	FASTA	342	37,864
	10 20 30 40 50 60 MVSVTRTVFG ELPSGGGTVE KFQLRSDQLS VDIISWGCTI TALQVKDRQG KATDVVLGFA 70 80 90 100 110 120 ELEGYLQKQP YFGAVVGRVA NRIAKGRFTI GGKEYLLPVN REPNSLHGGF TGFDKVLWTP 130 140 150 160 170 180 QVLTNGVQFF RVSPDGEEGY PGELKVWVTY TLDGGELVIN YRAQASQTTP VNLTNHSYFN 190 200 210 220 230 240 LAGQGSPNIY DHEVTIAADA YLPVDETLIP TGVIAPVEGT AFDLRKPVEL GTHLQDYHIH 250 260 270 280 290 300 GFDHNFCLKE LKEKKFCARV RHAASGRILE VYTTQPGVQF YTGNFLDGTL KGKNGAVYPK 310 320 330 340 HSGLCLETQY WPDSVNQPQF PPALLRPGEE YNHTTWFKFS VA

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE34366.1. Tissue: Inner ear EMBL BAE34366.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE34366.1. Tissue: Inner ear EMBL BAE34366.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE34366.1. Tissue: Inner ear EMBL BAE34366.1.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE34366.1. Tissue: Inner ear EMBL BAE34366.1.
[5]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE34366.1. Tissue: Inner ear EMBL BAE34366.1.
[6]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE34366.1. Tissue: Inner ear EMBL BAE34366.1.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE34366.1. Tissue: Inner ear EMBL BAE34366.1.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE34366.1. Tissue: Inner ear EMBL BAE34366.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK158120 mRNA. Translation: BAE34366.1.
IPI	IPI00169670.
UniGene	Mm.29098.
3D structure databases
ProteinModelPortal	Q3TZ44.
SMR	Q3TZ44. Positions 1-342.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000040580.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:2442420. Galm.
Phylogenomic databases
HOVERGEN	HBG051697.
InParanoid	Q3TZ44.
Enzyme and pathway databases
UniPathway	UPA00242.
Gene expression databases
Genevestigator	Q3TZ44.
Family and domain databases
Gene3D	2.70.98.10. 1 hit.
InterPro	IPR018052. Ald1_epimerase_CS. IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. Glyco_hydro-type_carb-bd_sub. [Graphical view]
PANTHER	PTHR10091. PTHR10091. 1 hit.
Pfam	PF01263. Aldose_epim. 1 hit. [Graphical view]
PIRSF	PIRSF005096. GALM. 1 hit.
SUPFAM	SSF74650. Gal_mut_like. 1 hit.
PROSITE	PS00545. ALDOSE_1_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	GALM. mouse.
SOURCE	Search...

Entry information

Entry name

Q3TZ44_MOUSE

Accession

Primary (citable) accession number: Q3TZ44

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)