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Protein
Submitted name:

Putative uncharacterized protein

Gene

Wif1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Submitted name:
Wnt inhibitory factor 1Imported
Gene namesi
Name:Wif1Imported
ORF Names:mCG_10113Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1344332. Wif1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501013809829 – 379Sequence analysisAdd BLAST351

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi182 ↔ 192PROSITE-ProRule annotation
Disulfide bondi200 ↔ 209PROSITE-ProRule annotation
Disulfide bondi214 ↔ 224PROSITE-ProRule annotation
Disulfide bondi232 ↔ 241PROSITE-ProRule annotation
Disulfide bondi246 ↔ 256PROSITE-ProRule annotation
Disulfide bondi278 ↔ 288PROSITE-ProRule annotation
Disulfide bondi296 ↔ 305PROSITE-ProRule annotation
Disulfide bondi310 ↔ 320PROSITE-ProRule annotation
Disulfide bondi328 ↔ 337PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000020218.
ExpressionAtlasiQ3TYU1. baseline and differential.

Structurei

3D structure databases

SMRiQ3TYU1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 177WIFInterPro annotationAdd BLAST140
Domaini178 – 210EGF-likeInterPro annotationAdd BLAST33
Domaini211 – 242EGF-likeInterPro annotationAdd BLAST32
Domaini243 – 271EGF-likeInterPro annotationAdd BLAST29
Domaini274 – 306EGF-likeInterPro annotationAdd BLAST33
Domaini307 – 338EGF-likeInterPro annotationAdd BLAST32

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IQQ0. Eukaryota.
ENOG41104IN. LUCA.
HOVERGENiHBG017335.
KOiK01691.
OMAiDKGIMAD.
OrthoDBiEOG091G08T8.

Family and domain databases

InterProiView protein in InterPro
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR003306. WIF.
IPR013309. Wnt-inh.
PfamiView protein in Pfam
PF12661. hEGF. 3 hits.
PF02019. WIF. 1 hit.
PRINTSiPR01901. WIFPROTEIN.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD013948. WIF. 1 hit.
SMARTiView protein in SMART
SM00181. EGF. 5 hits.
SM00469. WIF. 1 hit.
PROSITEiView protein in PROSITE
PS00022. EGF_1. 3 hits.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 5 hits.
PS50814. WIF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TYU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRRAFPAF ALRLWSILPC LLLLRADAGQ PPEESLYLWI DAHQARVLIG
60 70 80 90 100
FEEDILIVSE GKMAPFTHDF RKAQQRMPAI PVNIHSMNFT WQAAGQAEYF
110 120 130 140 150
YEFLSLRSLD KGIMADPTVN VPLLGTVPHK ASVVQVGFPC LGKQDGVAAF
160 170 180 190 200
EVNVIVMNSE GNTILRTPQN AIFFKTCQQA ECPGGCRNGG FCNERRVCEC
210 220 230 240 250
PDGFYGPHCE KALCIPRCMN GGLCVTPGFC ICPPGFYGVN CDKANCSTTC
260 270 280 290 300
FNGGTCFYPG KCICPPGLEG EQCELSKCPQ PCRNGGKCIG KSKCKCPKGY
310 320 330 340 350
QGDLCSKPVC EPGCGAHGTC HEPNKCQCRE GWHGRHCNKR YGASLMHAPR
360 370
PAGAGLERHT PSLKKAEDRR DPPESNYIW
Length:379
Mass (Da):41,590
Last modified:October 11, 2005 - v1
Checksum:iE3765F2642B2BC9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK142443 mRNA. Translation: BAE25067.1.
AK158359 mRNA. Translation: BAE34471.1.
CH466578 Genomic DNA. Translation: EDL24411.1.
RefSeqiNP_036045.1. NM_011915.2.
UniGeneiMm.32831.

Genome annotation databases

GeneIDi24117.
KEGGimmu:24117.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ3TYU1_MOUSE
AccessioniPrimary (citable) accession number: Q3TYU1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 5, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation