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Protein
Submitted name:

Wnt inhibitory factor 1

Gene

Wif1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Wnt inhibitory factor 1Imported
Gene namesi
Name:Wif1Imported
ORF Names:mCG_10113Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1344332 Wif1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501430915729 – 379Sequence analysisAdd BLAST351

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi182 ↔ 192PROSITE-ProRule annotation
Disulfide bondi200 ↔ 209PROSITE-ProRule annotation
Disulfide bondi214 ↔ 224PROSITE-ProRule annotation
Disulfide bondi232 ↔ 241PROSITE-ProRule annotation
Disulfide bondi246 ↔ 256PROSITE-ProRule annotation
Disulfide bondi278 ↔ 288PROSITE-ProRule annotation
Disulfide bondi296 ↔ 305PROSITE-ProRule annotation
Disulfide bondi310 ↔ 320PROSITE-ProRule annotation
Disulfide bondi328 ↔ 337PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000020218
ExpressionAtlasiQ3TYU1 baseline and differential

Structurei

3D structure databases

SMRiQ3TYU1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 177WIFInterPro annotationAdd BLAST140
Domaini178 – 210EGF-likeInterPro annotationAdd BLAST33
Domaini211 – 242EGF-likeInterPro annotationAdd BLAST32
Domaini243 – 271EGF-likeInterPro annotationAdd BLAST29
Domaini274 – 306EGF-likeInterPro annotationAdd BLAST33
Domaini307 – 338EGF-likeInterPro annotationAdd BLAST32

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IQQ0 Eukaryota
ENOG41104IN LUCA
HOVERGENiHBG017335
KOiK01691
OMAiDKGIMAD
OrthoDBiEOG091G08T8

Family and domain databases

Gene3Di2.60.40.2170, 1 hit
InterProiView protein in InterPro
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR003306 WIF
IPR038677 WIF_sf
IPR013309 Wnt-inh
PfamiView protein in Pfam
PF12661 hEGF, 3 hits
PF02019 WIF, 1 hit
PRINTSiPR01901 WIFPROTEIN
ProDomiView protein in ProDom or Entries sharing at least one domain
PD013948 WIF, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 5 hits
SM00469 WIF, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 3 hits
PS01186 EGF_2, 3 hits
PS50026 EGF_3, 5 hits
PS50814 WIF, 1 hit

Sequencei

Sequence statusi: Complete.

Q3TYU1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRRAFPAF ALRLWSILPC LLLLRADAGQ PPEESLYLWI DAHQARVLIG
60 70 80 90 100
FEEDILIVSE GKMAPFTHDF RKAQQRMPAI PVNIHSMNFT WQAAGQAEYF
110 120 130 140 150
YEFLSLRSLD KGIMADPTVN VPLLGTVPHK ASVVQVGFPC LGKQDGVAAF
160 170 180 190 200
EVNVIVMNSE GNTILRTPQN AIFFKTCQQA ECPGGCRNGG FCNERRVCEC
210 220 230 240 250
PDGFYGPHCE KALCIPRCMN GGLCVTPGFC ICPPGFYGVN CDKANCSTTC
260 270 280 290 300
FNGGTCFYPG KCICPPGLEG EQCELSKCPQ PCRNGGKCIG KSKCKCPKGY
310 320 330 340 350
QGDLCSKPVC EPGCGAHGTC HEPNKCQCRE GWHGRHCNKR YGASLMHAPR
360 370
PAGAGLERHT PSLKKAEDRR DPPESNYIW
Length:379
Mass (Da):41,590
Last modified:October 11, 2005 - v1
Checksum:iE3765F2642B2BC9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK142443 mRNA Translation: BAE25067.1
AK158359 mRNA Translation: BAE34471.1
CH466578 Genomic DNA Translation: EDL24411.1
RefSeqiNP_036045.1, NM_011915.2
UniGeneiMm.32831

Genome annotation databases

GeneIDi24117
KEGGimmu:24117

Similar proteinsi

Entry informationi

Entry nameiQ3TYU1_MOUSE
AccessioniPrimary (citable) accession number: Q3TYU1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health