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Protein
Submitted name:

Putative uncharacterized protein

Gene

Lipc

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei84 – 841NucleophileUniRule annotation
Active sitei110 – 1101Charge relay systemUniRule annotation
Active sitei195 – 1951Charge relay systemUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Protein family/group databases

ESTHERimouse-1hlip. Hepatic_Lipase.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:LipcImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96216. Lipc.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034731.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini268 – 402135PLATInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the AB hydrolase superfamily. Lipase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IIHP. Eukaryota.
ENOG4110MCZ. LUCA.
HOVERGENiHBG002259.

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR002333. Lipase_hep.
IPR016272. Lipase_LIPH.
IPR013818. Lipase_N.
IPR001024. PLAT/LH2_dom.
IPR000734. TAG_lipase.
[Graphical view]
PANTHERiPTHR11610. PTHR11610. 2 hits.
PTHR11610:SF2. PTHR11610:SF2. 2 hits.
PfamiPF00151. Lipase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PIRSFiPIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
PRINTSiPR00824. HEPLIPASE.
PR00821. TAGLIPASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF49723. SSF49723. 1 hit.
SSF53474. SSF53474. 1 hit.
PROSITEiPS50095. PLAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3TYU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIHGWSVDG LLENWIWKIV SALKSRQSQP VNVGLVDWIS LAYQHYTIAV
60 70 80 90 100
QNTRIVGQDV AALLLWLEES AKFSRSKVHL IGYSLGAHVS GFAGSSMDGK
110 120 130 140 150
NKIGRITGLD PAGPMFEGTS PNERLSPDDA NFVDAIHTFT REHMGLSVGI
160 170 180 190 200
KQPIAHYDFY PNGGSFQPGC HFLELYKHIA EHGLNAITQT IKCAHERSVH
210 220 230 240 250
LFIDSLQHSD LQSIGFQCSD MGSFSQGLCL SCKKGRCNTL GYDIRKDRSG
260 270 280 290 300
KSKRLFLITR AQSPFKVYHY QFKIQFINQI EKPVEPTFTM SLLGTKEEIK
310 320 330 340 350
RIPITLGEGI TSNKTYSFLI TLDKDIGELI LLKFKWENSA VWANVWNTVQ
360 370 380 390 400
TIMLWGIEPH HSGLILKTIW VKAGETQQRM TFCPENLDDL QLHPSQEKVF
410 420
VNCEVKSKRL TESKEQMSQE THAKK
Length:425
Mass (Da):48,009
Last modified:October 11, 2005 - v1
Checksum:i095637E1F3DB2B86
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK158285 mRNA. Translation: BAE34446.1.
AK158360 mRNA. Translation: BAE34472.1.
RefSeqiXP_011240966.1. XM_011242664.1.
UniGeneiMm.390187.

Genome annotation databases

GeneIDi15450.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK158285 mRNA. Translation: BAE34446.1.
AK158360 mRNA. Translation: BAE34472.1.
RefSeqiXP_011240966.1. XM_011242664.1.
UniGeneiMm.390187.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034731.

Protein family/group databases

ESTHERimouse-1hlip. Hepatic_Lipase.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15450.

Organism-specific databases

CTDi3990.
MGIiMGI:96216. Lipc.

Phylogenomic databases

eggNOGiENOG410IIHP. Eukaryota.
ENOG4110MCZ. LUCA.
HOVERGENiHBG002259.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di2.60.60.20. 1 hit.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR002333. Lipase_hep.
IPR016272. Lipase_LIPH.
IPR013818. Lipase_N.
IPR001024. PLAT/LH2_dom.
IPR000734. TAG_lipase.
[Graphical view]
PANTHERiPTHR11610. PTHR11610. 2 hits.
PTHR11610:SF2. PTHR11610:SF2. 2 hits.
PfamiPF00151. Lipase. 1 hit.
PF01477. PLAT. 1 hit.
[Graphical view]
PIRSFiPIRSF000865. Lipoprotein_lipase_LIPH. 1 hit.
PRINTSiPR00824. HEPLIPASE.
PR00821. TAGLIPASE.
SMARTiSM00308. LH2. 1 hit.
[Graphical view]
SUPFAMiSSF49723. SSF49723. 1 hit.
SSF53474. SSF53474. 1 hit.
PROSITEiPS50095. PLAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Inner earImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Inner earImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Inner earImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Inner earImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Inner earImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Inner earImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Inner earImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Inner earImported.

Entry informationi

Entry nameiQ3TYU0_MOUSE
AccessioniPrimary (citable) accession number: Q3TYU0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 11, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.