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Protein
Submitted name:

Apolipoprotein E, isoform CRA_h

Gene

Apoe

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processLipid transportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Apolipoprotein E, isoform CRA_hImported
Gene namesi
Name:ApoeImported
ORF Names:mCG_4867Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88057 Apoe

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501430912419 – 311Sequence analysisAdd BLAST293

Keywords - PTMi

LipoproteinImported

Expressioni

Gene expression databases

BgeeiENSMUSG00000002985

Interactioni

GO - Molecular functioni

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili67 – 87Sequence analysisAdd BLAST21
Coiled coili111 – 138Sequence analysisAdd BLAST28
Coiled coili148 – 175Sequence analysisAdd BLAST28
Coiled coili232 – 259Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the apolipoprotein A1/A4/E family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IVK0 Eukaryota
ENOG4111MYC LUCA
HOVERGENiHBG010582
KOiK04524
OMAiMGSRTRD
OrthoDBiEOG091G0IA5

Family and domain databases

InterProiView protein in InterPro
IPR000074 ApoA_E
PfamiView protein in Pfam
PF01442 Apolipoprotein, 1 hit

Sequencei

Sequence statusi: Complete.

Q3TXU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKALWAVLLV TLLTGCLAEG EPEVTDQLEW QSNQPWEQAL NRFWDYLRWV
60 70 80 90 100
QTLSDQVQEE LQSSQVTQEL TALMEDTMTE VKAYKKELEE QLGPVAEETR
110 120 130 140 150
ARLGKEVQAA QARLGADMED LRNRLGQYRN EVHTMLGQST EEIRARLSTH
160 170 180 190 200
LRKMRKRLMR DAEDLQKRLA VYKAGAREGA ERGVSAIRER LGPLVEQGRQ
210 220 230 240 250
RTANLGAGAA QPLRDRAQAF GDRIRGRLEE VGNQARDRLE EVREHMEEVR
260 270 280 290 300
SKMEEQTQQI RLQAEIFQAR LKGWFEPIVE DMHRQWANLM EKIQASVATN
310
PIITPVAQEN Q
Length:311
Mass (Da):35,867
Last modified:October 11, 2005 - v1
Checksum:i3B36FA897CC34170
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK134921 mRNA Translation: BAE22338.1
AK159105 mRNA Translation: BAE34821.1
AK159517 mRNA Translation: BAE35147.1
CH466639 Genomic DNA Translation: EDL23183.1
CH466639 Genomic DNA Translation: EDL23184.1
RefSeqiNP_001292748.1, NM_001305819.1
NP_001292772.1, NM_001305843.1
NP_001292773.1, NM_001305844.1
NP_033826.2, NM_009696.4
UniGeneiMm.305152

Genome annotation databases

GeneIDi11816
KEGGimmu:11816

Similar proteinsi

Entry informationi

Entry nameiQ3TXU4_MOUSE
AccessioniPrimary (citable) accession number: Q3TXU4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 25, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health