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Protein
Submitted name:

Cysteine rich protein 61

Gene

Cyr61

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteine rich protein 61Imported
Gene namesi
Name:Cyr61Imported
ORF Names:mCG_7789Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88613. Cyr61.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501084333125 – 379Sequence analysisAdd BLAST355

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000028195.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 94IGFBP N-terminalInterPro annotationAdd BLAST73
Domaini98 – 164VWFCInterPro annotationAdd BLAST67
Domaini284 – 358CTCK (C-terminal cystine knot-like)InterPro annotationAdd BLAST75

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IIY0. Eukaryota.
ENOG41119KZ. LUCA.
HOVERGENiHBG000635.
KOiK06829.
OMAiKCIVQTT.
OrthoDBiEOG091G0SQP.

Family and domain databases

InterProiView protein in InterPro
IPR006207. Cys_knot_C.
IPR006208. Glyco_hormone_CN.
IPR009030. Growth_fac_rcpt_.
IPR000867. IGFBP-like.
IPR012395. IGFBP_CNN.
IPR017891. Insulin_GF-bd_Cys-rich_CS.
IPR000884. TSP1_rpt.
IPR001007. VWF_dom.
PfamiView protein in Pfam
PF00007. Cys_knot. 1 hit.
PF00219. IGFBP. 1 hit.
PF00093. VWC. 1 hit.
PIRSFiPIRSF036495. IGFBP_rP_CNN. 1 hit.
SMARTiView protein in SMART
SM00041. CT. 1 hit.
SM00121. IB. 1 hit.
SM00209. TSP1. 1 hit.
SM00214. VWC. 1 hit.
SUPFAMiSSF57184. SSF57184. 1 hit.
SSF82895. SSF82895. 1 hit.
PROSITEiView protein in PROSITE
PS01185. CTCK_1. 1 hit.
PS01225. CTCK_2. 1 hit.
PS00222. IGFBP_N_1. 1 hit.
PS51323. IGFBP_N_2. 1 hit.
PS50092. TSP1. 1 hit.
PS01208. VWFC_1. 1 hit.
PS50184. VWFC_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TX21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSTFRTLA VAVTLLHLTR LALSTCPAAC HCPLEAPKCA PGVGLVRDGC
60 70 80 90 100
GCCKVCAKQL NEDCSKTQPC DHTKGLECNF GASSTALKGI CRAQSEGRPC
110 120 130 140 150
EYNSRIYQNG ESFQPNCKHQ CTCIDGAVGC IPLCPQELSL PNLGCPNPRL
160 170 180 190 200
VKVSGQCCEE WVCDEDSIKD SLDDQDDLLG LDASEVELTR NNELIAIGKG
210 220 230 240 250
SSLKRLPVFG TEPRVLFNPL HAHGQKCIVQ TTSWSQCSKS CGTGISTRVT
260 270 280 290 300
NDNPECRLVK ETRICEVRPC GQPVYSSLKK GKKCSKTKKS PEPVRFTYAG
310 320 330 340 350
CSSVKKYRPK YCGSCVDGRC CTPLQTRTVK MRFRCEDGEM FSKNVMMIQS
360 370
CKCNYNCPHP NEASFRLYSL FNDIHKFRD
Length:379
Mass (Da):41,709
Last modified:October 11, 2005 - v1
Checksum:iFA6B5014B56A8EE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK156723 mRNA. Translation: BAE33819.1.
AK159452 mRNA. Translation: BAE35095.1.
CH466532 Genomic DNA. Translation: EDL11998.1.
RefSeqiNP_034646.1. NM_010516.2.
UniGeneiMm.1231.

Genome annotation databases

GeneIDi16007.
KEGGimmu:16007.

Similar proteinsi

Entry informationi

Entry nameiQ3TX21_MOUSE
AccessioniPrimary (citable) accession number: Q3TX21
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: August 30, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation