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Protein
Submitted name:

AP-2 complex subunit mu

Gene

Ap2m1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei339Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei341Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei343Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei352Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei354Phosphatidylinositol lipid headgroupUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transportSAAS annotation, Transport

Keywords - Ligandi

Lipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AP-2 complex subunit muImported
Submitted name:
Adaptor protein complex AP-2, mu1, isoform CRA_aImported
Gene namesi
Name:Ap2m1Imported
ORF Names:mCG_128452Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1298405. Ap2m1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000022841.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007216.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini168 – 432MHD (mu homology)InterPro annotationAdd BLAST265

Sequence similaritiesi

Belongs to the adaptor complexes medium subunit family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0937. Eukaryota.
ENOG410XPFS. LUCA.
GeneTreeiENSGT00530000062779.
HOVERGENiHBG050516.

Family and domain databases

InterProiIPR022775. AP_mu_sigma_su.
IPR001392. Clathrin_mu.
IPR018240. Clathrin_mu_CS.
IPR011012. Longin-like_dom.
IPR028565. MHD.
[Graphical view]
PfamiPF00928. Adap_comp_sub. 1 hit.
PF01217. Clat_adaptor_s. 1 hit.
[Graphical view]
PIRSFiPIRSF005992. Clathrin_mu. 1 hit.
PRINTSiPR00314. CLATHRINADPT.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiPS00990. CLAT_ADAPTOR_M_1. 1 hit.
PS00991. CLAT_ADAPTOR_M_2. 1 hit.
PS51072. MHD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3TWV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGGLFIYNH KGEVLISRVY RDDIGRNAVD AFRVNVIHAR QQVRSPVTNI
60 70 80 90 100
ARTSFFHVKR SNIWLAAVTK QNVNAAMVFE FLYKMCDVMA AYFGKISEEN
110 120 130 140 150
IKNNFVLIYE LLDEILDFGY PQNSETGALK TFITQQGIKS QTKEEQSQIT
160 170 180 190 200
SQVTGQIGWR REGIKYRRNE LFLDVLESVN LLMSPQGQVL SAHVSGRVVM
210 220 230 240 250
KSYLSGMPEC KFGMNDKIVI EKQGKGTADE TSKSGKQSIA IDDCTFHQCV
260 270 280 290 300
RLSKFDSERS ISFIPPDGEF ELMRYRTTKD IILPFRVIPL VREVGRTKLE
310 320 330 340 350
VKVVIKSNFK PSLLAQKIEV RIPTPLNTSG VQVICMKGKA KYKASENAIV
360 370 380 390 400
WKIKRMAGMK ESQISAEIEL LPTNDKKKWA RPPISMNFEV PFAPSGLKVR
410 420 430
YLKVFEPKLN YSDHDVIKWV RYIGRSGIYE TRC
Length:433
Mass (Da):49,389
Last modified:October 11, 2005 - v1
Checksum:i76399E78B0AC7E8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087898 Genomic DNA. No translation available.
AK159534 mRNA. Translation: BAE35162.1.
CH466521 Genomic DNA. Translation: EDK97571.1.
RefSeqiNP_001289899.1. NM_001302970.1.
UniGeneiMm.18946.

Genome annotation databases

EnsembliENSMUST00000090023; ENSMUSP00000087477; ENSMUSG00000022841.
GeneIDi11773.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087898 Genomic DNA. No translation available.
AK159534 mRNA. Translation: BAE35162.1.
CH466521 Genomic DNA. Translation: EDK97571.1.
RefSeqiNP_001289899.1. NM_001302970.1.
UniGeneiMm.18946.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007216.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000090023; ENSMUSP00000087477; ENSMUSG00000022841.
GeneIDi11773.

Organism-specific databases

CTDi1173.
MGIiMGI:1298405. Ap2m1.

Phylogenomic databases

eggNOGiKOG0937. Eukaryota.
ENOG410XPFS. LUCA.
GeneTreeiENSGT00530000062779.
HOVERGENiHBG050516.

Miscellaneous databases

ChiTaRSiAp2m1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022841.

Family and domain databases

InterProiIPR022775. AP_mu_sigma_su.
IPR001392. Clathrin_mu.
IPR018240. Clathrin_mu_CS.
IPR011012. Longin-like_dom.
IPR028565. MHD.
[Graphical view]
PfamiPF00928. Adap_comp_sub. 1 hit.
PF01217. Clat_adaptor_s. 1 hit.
[Graphical view]
PIRSFiPIRSF005992. Clathrin_mu. 1 hit.
PRINTSiPR00314. CLATHRINADPT.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiPS00990. CLAT_ADAPTOR_M_1. 1 hit.
PS00991. CLAT_ADAPTOR_M_2. 1 hit.
PS51072. MHD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3TWV4_MOUSE
AccessioniPrimary (citable) accession number: Q3TWV4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 30, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.