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Protein
Submitted name:

Retinoic acid receptor RXR-beta

Gene

Rxrb

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi189 – 264Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoic acid receptor RXR-betaImported
Gene namesi
Name:RxrbImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:98215. Rxrb.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000039656.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini189 – 264Nuclear receptorInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00760000118948.
HOGENOMiHOG000260821.
HOVERGENiHBG005606.
OMAiSAVNEEM.
OrthoDBiEOG091G0YX6.
TreeFamiTF352097.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR035500. NHR_like_domain.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR000003. Retinoid-X_rcpt/HNF4.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00545. RETINOIDXR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TWJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWATRPPFL PPRHAAGQCG PVGVRKEMHC GVASRWRRRR PWLDPAAAAA
60 70 80 90 100
AAGEQQALEP EPGEAGRDGM GDSGRDSRSP DSSSPNPLSQ GIRPSSPPGP
110 120 130 140 150
PLTPSAPPPP MPPPPLGSPF PVISSSMGSP GLPPPAPPGF SGPVSSPQIN
160 170 180 190 200
STVSLPGGGS GPPEDVKPPV LGVRGLHCPP PPGGPGAGKR LCAICGDRSS
210 220 230 240 250
GKHYGVYSCE GCKGFFKRTI RKDLTYSCRD NKDCTVDKRQ RNRCQYCRYQ
260 270 280 290 300
KCLATGMKRE AVQEERQRGK DKDGDGDGAG GAPEEMPVDR ILEAELAVEQ
310 320 330 340 350
KSDQGVEGPG ATGGGGSSPN DPVTNICQAA DKQLFTLVEW AKRIPHFSSL
360 370 380 390 400
PLDDQVILLR AGWNELLIAS FSHRSIDVRD GILLATGLHV HRNSAHSAGV
410 420 430 440 450
GAIFDRSLSR VLTELVSKMR DMRMDKTELG CLRAIILFNP DAKGLSNPGE
460 470 480 490 500
VEILREKVYA SLETYCKQKY PEQQGRFAKL LLRLPALRSI GLKCLEHLFF
510 520
FKLIGDTPID TFLMEMLEAP HQLA
Length:524
Mass (Da):56,309
Last modified:October 11, 2005 - v1
Checksum:iE248BB5342F3A6C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974462 Genomic DNA. No translation available.
AK159671 mRNA. Translation: BAE35275.1.
RefSeqiNP_001192143.1. NM_001205214.1.
UniGeneiMm.1243.

Genome annotation databases

EnsembliENSMUST00000044858; ENSMUSP00000036585; ENSMUSG00000039656.
GeneIDi20182.
UCSCiuc008cay.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ3TWJ1_MOUSE
AccessioniPrimary (citable) accession number: Q3TWJ1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 25, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported