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Q3TUA9 (SG196_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inactive protein kinase-like protein SgK196
Alternative name(s):
Sugen kinase 196
Gene names
Name:Sgk196
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Domain

The protein kinase domain is predicted to be catalytically inactive.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 349349Probable inactive protein kinase-like protein SgK196
PRO_0000262998

Regions

Transmembrane20 – 4223Helical; Potential
Domain80 – 349270Protein kinase

Experimental info

Sequence conflict51H → Y in BAC29393. Ref.1
Sequence conflict1581N → D in BAE42167. Ref.1
Sequence conflict2391V → I in AAH27296. Ref.2
Sequence conflict2761N → T in BAE42167. Ref.1
Sequence conflict3191E → K in AAH27296. Ref.2
Sequence conflict3351H → Q in BAE36062. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q3TUA9 [UniParc].

Last modified November 28, 2006. Version 2.
Checksum: 0E8683A6DBAAE9C3

FASTA34939,969
        10         20         30         40         50         60 
MGQQHGTRNG LTHRELPRGV GLLLAMALMN VALYLCLDQL FISPGRSTAD SRRCPPGYFR 

        70         80         90        100        110        120 
MGRMRNCSRW LSCEELRTEV RQLKRVGEGA VKRVFLSEWK EHKVALSRLT RLEMKEDFLH 

       130        140        150        160        170        180 
GLQMLKSLQS EHVVTLVGYC EEDGTILTEY HPLGSLSNLE ETLNLSKYQD VNTWQHRLQL 

       190        200        210        220        230        240 
AMEYVSIINY LHHSPLGTRV MCDSNDLPKT LSQYLLTSNF SIVANDLDAL PLVDHDSGVL 

       250        260        270        280        290        300 
IKCGHRELHG DFVAPEQLWP YGEDTPFQDD LMPSYNEKVD IWKIPDVSSF LLGHVEGSDM 

       310        320        330        340 
VRFHLFDIHK ACKSQIPAER PTAQNVLDAY QRVFHSLRDT VMSQTKEML

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J and NOD.
Tissue: Aorta, Brain, Brain cortex, Cerebellum, Testis and Vein.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Czech II.
Tissue: Mammary gland.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK036348 mRNA. Translation: BAC29393.1.
AK015374 mRNA. Translation: BAB29817.1.
AK032677 mRNA. Translation: BAC27984.1.
AK043620 mRNA. Translation: BAC31598.1.
AK138952 mRNA. Translation: BAE23832.1.
AK160873 mRNA. Translation: BAE36062.1.
AK170994 mRNA. Translation: BAE42167.1.
BC027296 mRNA. Translation: AAH27296.1.
IPIIPI00459832.
RefSeqNP_083313.1. NM_029037.4.
UniGeneMm.17631.

3D structure databases

ProteinModelPortalQ3TUA9.
SMRQ3TUA9. Positions 49-341.
ModBaseSearch...

PTM databases

PhosphoSiteQ3TUA9.

Proteomic databases

PRIDEQ3TUA9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000061850; ENSMUSP00000053802; ENSMUSG00000037251.
GeneID74653.
KEGGmmu:74653.
UCSCuc009lhh.1. mouse.

Organism-specific databases

MGIMGI:1921903. 4930444A02Rik.

Phylogenomic databases

eggNOGNOG43701.
GeneTreeENSGT00390000004945.
HOGENOMHOG000006624.
HOVERGENHBG093945.
InParanoidQ3TUA9.
OMAEGSDMVR.
OrthoDBEOG4GB76K.

Gene expression databases

BgeeQ3TUA9.
CleanExMM_4930444A02RIK.
GenevestigatorQ3TUA9.
GermOnlineENSMUSG00000037251. Mus musculus.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_cat_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMSSF56112. Kinase_like. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio341310.
SOURCESearch...

Entry information

Entry nameSG196_MOUSE
AccessionPrimary (citable) accession number: Q3TUA9
Secondary accession number(s): Q3TBZ0 expand/collapse secondary AC list , Q8BZ83, Q8R2S2, Q9D5G4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 28, 2006
Last modified: May 1, 2013
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

Human and mouse protein kinases

Human and mouse protein kinases: classification and index

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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