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Q3TTB4

- Q3TTB4_MOUSE

UniProt

Q3TTB4 - Q3TTB4_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Hk1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. fructokinase activity Source: RefGenome
    3. glucokinase activity Source: MGI
    4. hexokinase activity Source: MGI
    5. mannokinase activity Source: RefGenome
    6. protein binding Source: MGI

    GO - Biological processi

    1. canonical glycolysis Source: MGI
    2. carbohydrate phosphorylation Source: GOC
    3. cellular glucose homeostasis Source: RefGenome
    4. glucose 6-phosphate metabolic process Source: GOC
    5. glycolytic process Source: MGI

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotation, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Hk1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:96103. Hk1.

    Subcellular locationi

    GO - Cellular componenti

    1. cilium Source: MGI
    2. cytosol Source: MGI
    3. membrane raft Source: MGI
    4. mitochondrion Source: MGI
    5. sperm principal piece Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiQ3TTB4.
    BgeeiQ3TTB4.
    GenevestigatoriQ3TTB4.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hexokinase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000162671.
    HOVERGENiHBG005020.
    KOiK00844.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 1 hit.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.
    PROSITEiPS00378. HEXOKINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3TTB4-1 [UniParc]FASTAAdd to Basket

    « Hide

    EGDEGRMCIN TEWGAFGDDG SLEDIRTEFD RELDRGSLNP GKQLFEKMVS    50
    GMYMGELVRL ILVKMAKESL LFEGRITPEL LTRGKFTTSD VAAIETDKEG 100
    VQNAKEILTR LGVEPSHDDC VSVQHVCTIV SFRSANLVAA TLGAILNRLR 150
    DNKGTPRLRT TVGVDGSLYK MHPQYSRRFH KTLRRLVPDS DVRFLLSESG 200
    SGKGAAMVTA VAYRLAEQHR QIEETLSHFR LSKQALMEVK KKLRSEMEMG 250
    LRKETNSRAT VKMLPSYVRS IPDGTEHGDF LALDLGGTNF RVLLVKIRSG 300
    KKRTVEMHNK IYSIPLEIMQ GTGDELFDHI VSCISDFLDY MGIKGPRMPL 350
    GFTFSFPCKQ TSLDCGILIT WTKGFKATDC VGHDVATLLR DAVKRREEFD 400
    LDVVAVVNDT VGTMMTCAYE EPSCEIGLIV GTGSNACYME EMKNVEMVEG 450
    NQGQMCINME WGAFGDNGCL DDIRTDFDKV VDEYSLNSGK QRFEKMISGM 500
    YLGEIVRNIL IDFTKKGFLF RGQISEPLKT RGIFETKFLS QIESDRLALL 550
    QVRAILQQLG LNSTCDDSIL VKTVCGVVSK RAAQLCGAGM AAVVEKIREN 600
    RGLDHLNVTV GVDGTLYKLH PHFSRIMHQT VKELSPKCTV SFLLSEDGSG 650
    KGAALITAVG VRLRGDPTNA 670
    Length:670
    Mass (Da):74,389
    Last modified:October 11, 2005 - v1
    Checksum:i712BD282A4C8914E
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK161466 mRNA. Translation: BAE36411.1.
    RefSeqiNP_001139572.1. NM_001146100.1.
    NP_034568.2. NM_010438.3.
    UniGeneiMm.196605.

    Genome annotation databases

    GeneIDi15275.
    KEGGimmu:15275.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK161466 mRNA. Translation: BAE36411.1 .
    RefSeqi NP_001139572.1. NM_001146100.1.
    NP_034568.2. NM_010438.3.
    UniGenei Mm.196605.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 15275.
    KEGGi mmu:15275.

    Organism-specific databases

    CTDi 3098.
    MGIi MGI:96103. Hk1.

    Phylogenomic databases

    HOGENOMi HOG000162671.
    HOVERGENi HBG005020.
    KOi K00844.

    Miscellaneous databases

    NextBioi 287905.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3TTB4.
    Bgeei Q3TTB4.
    Genevestigatori Q3TTB4.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 1 hit.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    PROSITEi PS00378. HEXOKINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.

    Entry informationi

    Entry nameiQ3TTB4_MOUSE
    AccessioniPrimary (citable) accession number: Q3TTB4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)