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Q3TTB4

- Q3TTB4_MOUSE

UniProt

Q3TTB4 - Q3TTB4_MOUSE

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Protein
Submitted name: Putative uncharacterized protein
Gene
Hk1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: MGI
  4. hexokinase activity Source: MGI
  5. mannokinase activity Source: RefGenome
  6. protein binding Source: MGI

GO - Biological processi

  1. canonical glycolysis Source: MGI
  2. carbohydrate phosphorylation Source: GOC
  3. cellular glucose homeostasis Source: RefGenome
  4. glucose 6-phosphate metabolic process Source: GOC
  5. glycolytic process Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotations, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Hk1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96103. Hk1.

Subcellular locationi

GO - Cellular componenti

  1. cilium Source: MGI
  2. cytosol Source: MGI
  3. membrane raft Source: MGI
  4. mitochondrion Source: MGI
  5. sperm principal piece Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ3TTB4.
BgeeiQ3TTB4.
GenevestigatoriQ3TTB4.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162671.
HOVERGENiHBG005020.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3TTB4-1 [UniParc]FASTAAdd to Basket

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EGDEGRMCIN TEWGAFGDDG SLEDIRTEFD RELDRGSLNP GKQLFEKMVS    50
GMYMGELVRL ILVKMAKESL LFEGRITPEL LTRGKFTTSD VAAIETDKEG 100
VQNAKEILTR LGVEPSHDDC VSVQHVCTIV SFRSANLVAA TLGAILNRLR 150
DNKGTPRLRT TVGVDGSLYK MHPQYSRRFH KTLRRLVPDS DVRFLLSESG 200
SGKGAAMVTA VAYRLAEQHR QIEETLSHFR LSKQALMEVK KKLRSEMEMG 250
LRKETNSRAT VKMLPSYVRS IPDGTEHGDF LALDLGGTNF RVLLVKIRSG 300
KKRTVEMHNK IYSIPLEIMQ GTGDELFDHI VSCISDFLDY MGIKGPRMPL 350
GFTFSFPCKQ TSLDCGILIT WTKGFKATDC VGHDVATLLR DAVKRREEFD 400
LDVVAVVNDT VGTMMTCAYE EPSCEIGLIV GTGSNACYME EMKNVEMVEG 450
NQGQMCINME WGAFGDNGCL DDIRTDFDKV VDEYSLNSGK QRFEKMISGM 500
YLGEIVRNIL IDFTKKGFLF RGQISEPLKT RGIFETKFLS QIESDRLALL 550
QVRAILQQLG LNSTCDDSIL VKTVCGVVSK RAAQLCGAGM AAVVEKIREN 600
RGLDHLNVTV GVDGTLYKLH PHFSRIMHQT VKELSPKCTV SFLLSEDGSG 650
KGAALITAVG VRLRGDPTNA 670
Length:670
Mass (Da):74,389
Last modified:October 11, 2005 - v1
Checksum:i712BD282A4C8914E
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK161466 mRNA. Translation: BAE36411.1.
RefSeqiNP_001139572.1. NM_001146100.1.
NP_034568.2. NM_010438.3.
UniGeneiMm.196605.

Genome annotation databases

GeneIDi15275.
KEGGimmu:15275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK161466 mRNA. Translation: BAE36411.1 .
RefSeqi NP_001139572.1. NM_001146100.1.
NP_034568.2. NM_010438.3.
UniGenei Mm.196605.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 15275.
KEGGi mmu:15275.

Organism-specific databases

CTDi 3098.
MGIi MGI:96103. Hk1.

Phylogenomic databases

HOGENOMi HOG000162671.
HOVERGENi HBG005020.
KOi K00844.

Miscellaneous databases

NextBioi 287905.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q3TTB4.
Bgeei Q3TTB4.
Genevestigatori Q3TTB4.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ3TTB4_MOUSE
AccessioniPrimary (citable) accession number: Q3TTB4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 3, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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