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Q3TTB4 (Q3TTB4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Hk1 MGI 96103
OrganismMus musculus (Mouse) EMBL BAE36411.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length670 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the hexokinase family. RuleBase RU004510

Ontologies

Keywords
   Biological processGlycolysis RuleBase RU004049 SAAS SAAS022672
   LigandATP-binding RuleBase RU004049 SAAS SAAS022672
Nucleotide-binding
   Molecular functionKinase RuleBase RU004049 SAAS SAAS022672
Transferase
Gene Ontology (GO)
   Biological_processcarbohydrate phosphorylation

Inferred from direct assay PubMed 15155459PubMed 18165236. Source: GOC

cellular glucose homeostasis

Inferred from Biological aspect of Ancestor. Source: RefGenome

glucose 6-phosphate metabolic process

Inferred from direct assay PubMed 18509164. Source: GOC

glycolytic process

Traceable author statement PubMed 12420306. Source: MGI

   Cellular_componentcilium

Inferred from direct assay PubMed 16687649. Source: MGI

cytosol

Inferred from direct assay PubMed 12420306. Source: MGI

membrane raft

Inferred from direct assay PubMed 19144954. Source: MGI

mitochondrion

Inferred from direct assay PubMed 12420306PubMed 14651853PubMed 17069463PubMed 18614015. Source: MGI

sperm principal piece

Inferred from direct assay PubMed 19889946. Source: MGI

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

fructokinase activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

glucokinase activity

Inferred from direct assay PubMed 18509164. Source: MGI

hexokinase activity

Inferred from direct assay PubMed 15155459PubMed 18165236. Source: MGI

mannokinase activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

protein binding

Inferred from physical interaction PubMed 19889946PubMed 23055941. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAE36411.1

Sequences

Sequence LengthMass (Da)Tools
Q3TTB4 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 712BD282A4C8914E

FASTA67074,389
        10         20         30         40         50         60 
EGDEGRMCIN TEWGAFGDDG SLEDIRTEFD RELDRGSLNP GKQLFEKMVS GMYMGELVRL 

        70         80         90        100        110        120 
ILVKMAKESL LFEGRITPEL LTRGKFTTSD VAAIETDKEG VQNAKEILTR LGVEPSHDDC 

       130        140        150        160        170        180 
VSVQHVCTIV SFRSANLVAA TLGAILNRLR DNKGTPRLRT TVGVDGSLYK MHPQYSRRFH 

       190        200        210        220        230        240 
KTLRRLVPDS DVRFLLSESG SGKGAAMVTA VAYRLAEQHR QIEETLSHFR LSKQALMEVK 

       250        260        270        280        290        300 
KKLRSEMEMG LRKETNSRAT VKMLPSYVRS IPDGTEHGDF LALDLGGTNF RVLLVKIRSG 

       310        320        330        340        350        360 
KKRTVEMHNK IYSIPLEIMQ GTGDELFDHI VSCISDFLDY MGIKGPRMPL GFTFSFPCKQ 

       370        380        390        400        410        420 
TSLDCGILIT WTKGFKATDC VGHDVATLLR DAVKRREEFD LDVVAVVNDT VGTMMTCAYE 

       430        440        450        460        470        480 
EPSCEIGLIV GTGSNACYME EMKNVEMVEG NQGQMCINME WGAFGDNGCL DDIRTDFDKV 

       490        500        510        520        530        540 
VDEYSLNSGK QRFEKMISGM YLGEIVRNIL IDFTKKGFLF RGQISEPLKT RGIFETKFLS 

       550        560        570        580        590        600 
QIESDRLALL QVRAILQQLG LNSTCDDSIL VKTVCGVVSK RAAQLCGAGM AAVVEKIREN 

       610        620        630        640        650        660 
RGLDHLNVTV GVDGTLYKLH PHFSRIMHQT VKELSPKCTV SFLLSEDGSG KGAALITAVG 

       670 
VRLRGDPTNA 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE36411.1.
Tissue: Testis EMBL BAE36411.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE36411.1.
Tissue: Testis EMBL BAE36411.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE36411.1.
Tissue: Testis EMBL BAE36411.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE36411.1.
Tissue: Testis EMBL BAE36411.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE36411.1.
Tissue: Testis EMBL BAE36411.1.
[6]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE36411.1.
Tissue: Testis EMBL BAE36411.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE36411.1.
Tissue: Testis EMBL BAE36411.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE36411.1.
Tissue: Testis EMBL BAE36411.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK161466 mRNA. Translation: BAE36411.1.
RefSeqNP_001139572.1. NM_001146100.1.
NP_034568.2. NM_010438.3.
UniGeneMm.196605.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID15275.
KEGGmmu:15275.

Organism-specific databases

CTD3098.
MGIMGI:96103. Hk1.

Phylogenomic databases

HOGENOMHOG000162671.
HOVERGENHBG005020.
KOK00844.

Gene expression databases

ArrayExpressQ3TTB4.
BgeeQ3TTB4.
GenevestigatorQ3TTB4.

Family and domain databases

InterProIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERPTHR19443. PTHR19443. 1 hit.
PfamPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSPR00475. HEXOKINASE.
PROSITEPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio287905.
SOURCESearch...

Entry information

Entry nameQ3TTB4_MOUSE
AccessionPrimary (citable) accession number: Q3TTB4
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)