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Q3TTB4

- Q3TTB4_MOUSE

UniProt

Q3TTB4 - Q3TTB4_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Hk1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: MGI
  4. hexokinase activity Source: MGI
  5. mannokinase activity Source: RefGenome

GO - Biological processi

  1. canonical glycolysis Source: MGI
  2. carbohydrate phosphorylation Source: GOC
  3. cellular glucose homeostasis Source: RefGenome
  4. glucose 6-phosphate metabolic process Source: GOC
  5. glycolytic process Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Hk1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96103. Hk1.

Subcellular locationi

GO - Cellular componenti

  1. cilium Source: MGI
  2. cytosol Source: MGI
  3. membrane raft Source: MGI
  4. mitochondrion Source: MGI
  5. sperm principal piece Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ3TTB4.
ExpressionAtlasiQ3TTB4. baseline and differential.
GenevestigatoriQ3TTB4.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162671.
HOVERGENiHBG005020.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3TTB4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
EGDEGRMCIN TEWGAFGDDG SLEDIRTEFD RELDRGSLNP GKQLFEKMVS
60 70 80 90 100
GMYMGELVRL ILVKMAKESL LFEGRITPEL LTRGKFTTSD VAAIETDKEG
110 120 130 140 150
VQNAKEILTR LGVEPSHDDC VSVQHVCTIV SFRSANLVAA TLGAILNRLR
160 170 180 190 200
DNKGTPRLRT TVGVDGSLYK MHPQYSRRFH KTLRRLVPDS DVRFLLSESG
210 220 230 240 250
SGKGAAMVTA VAYRLAEQHR QIEETLSHFR LSKQALMEVK KKLRSEMEMG
260 270 280 290 300
LRKETNSRAT VKMLPSYVRS IPDGTEHGDF LALDLGGTNF RVLLVKIRSG
310 320 330 340 350
KKRTVEMHNK IYSIPLEIMQ GTGDELFDHI VSCISDFLDY MGIKGPRMPL
360 370 380 390 400
GFTFSFPCKQ TSLDCGILIT WTKGFKATDC VGHDVATLLR DAVKRREEFD
410 420 430 440 450
LDVVAVVNDT VGTMMTCAYE EPSCEIGLIV GTGSNACYME EMKNVEMVEG
460 470 480 490 500
NQGQMCINME WGAFGDNGCL DDIRTDFDKV VDEYSLNSGK QRFEKMISGM
510 520 530 540 550
YLGEIVRNIL IDFTKKGFLF RGQISEPLKT RGIFETKFLS QIESDRLALL
560 570 580 590 600
QVRAILQQLG LNSTCDDSIL VKTVCGVVSK RAAQLCGAGM AAVVEKIREN
610 620 630 640 650
RGLDHLNVTV GVDGTLYKLH PHFSRIMHQT VKELSPKCTV SFLLSEDGSG
660 670
KGAALITAVG VRLRGDPTNA
Length:670
Mass (Da):74,389
Last modified:October 11, 2005 - v1
Checksum:i712BD282A4C8914E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK161466 mRNA. Translation: BAE36411.1.
RefSeqiNP_001139572.1. NM_001146100.1.
NP_034568.2. NM_010438.3.
UniGeneiMm.196605.

Genome annotation databases

GeneIDi15275.
KEGGimmu:15275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK161466 mRNA. Translation: BAE36411.1 .
RefSeqi NP_001139572.1. NM_001146100.1.
NP_034568.2. NM_010438.3.
UniGenei Mm.196605.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 15275.
KEGGi mmu:15275.

Organism-specific databases

CTDi 3098.
MGIi MGI:96103. Hk1.

Phylogenomic databases

HOGENOMi HOG000162671.
HOVERGENi HBG005020.
KOi K00844.

Miscellaneous databases

NextBioi 287905.
SOURCEi Search...

Gene expression databases

Bgeei Q3TTB4.
ExpressionAtlasi Q3TTB4. baseline and differential.
Genevestigatori Q3TTB4.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ3TTB4_MOUSE
AccessioniPrimary (citable) accession number: Q3TTB4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)