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Protein
Submitted name:

Prolactin, isoform CRA_b

Gene

Prl

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHormoneUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Prolactin, isoform CRA_bImported
Gene namesi
Name:PrlImported
ORF Names:mCG_15525Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97762. Prl.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_501084332031 – 227Sequence analysisAdd BLAST197

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410II74. Eukaryota.
ENOG410XU1S. LUCA.
HOGENOMiHOG000264241.
HOVERGENiHBG104895.
KOiK05439.

Family and domain databases

InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR001400. Somatotropin/Prolactin.
IPR018116. Somatotropin_CS.
PANTHERiPTHR11417. PTHR11417. 1 hit.
PfamiView protein in Pfam
PF00103. Hormone_1. 1 hit.
PRINTSiPR00836. SOMATOTROPIN.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00338. SOMATOTROPIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TT66-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMNSQGSAQ KGTLLLLLIS NLLFCQNVQP LPICSAGDCQ TSLRELFDRV
60 70 80 90 100
VILSHYIHTL YTDMFIEFDK QYVQDREFMV KVINDCPTSS LATPEDKEQA
110 120 130 140 150
LKVPPEVLLN LILSLVQSSS DPLFQLITGV GGIQEAPEYI LSRAKEIEEQ
160 170 180 190 200
NKQLLEGVEK IISQAYPEAK GNGIYFVWSQ LPSLQGVDEE SKILSLRNTI
210 220
RCLRRDSHKV DNFLKVLRCQ IAHQNNC
Length:227
Mass (Da):25,658
Last modified:October 11, 2005 - v1
Checksum:iCF99840CA760FA7F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK133645 mRNA. Translation: BAE21763.1.
AK161553 mRNA. Translation: BAE36459.1.
AK161594 mRNA. Translation: BAE36481.1.
CH466561 Genomic DNA. Translation: EDL32453.1.
RefSeqiNP_001157002.1. NM_001163530.1.
UniGeneiMm.1270.

Genome annotation databases

GeneIDi19109.
KEGGimmu:19109.
UCSCiuc007pxc.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ3TT66_MOUSE
AccessioniPrimary (citable) accession number: Q3TT66
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: August 30, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)