Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CD4 antigen, isoform CRA_a

Gene

Cd4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD4 antigen, isoform CRA_aImported
Gene namesi
Name:Cd4Imported
ORF Names:mCG_134308Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88335 Cd4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei395 – 421HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501430912127 – 457Sequence analysisAdd BLAST431

Proteomic databases

MaxQBiQ3TSV7

Expressioni

Gene expression databases

BgeeiENSMUSG00000023274
ExpressionAtlasiQ3TSV7 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3TSV7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 122Ig-likeInterPro annotationAdd BLAST89

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9F Eukaryota
ENOG410YWI4 LUCA
HOVERGENiHBG005281
KOiK06454
OMAiPEAGMWQ
OrthoDBiEOG091G0AZL

Family and domain databases

Gene3Di2.60.40.10, 4 hits
InterProiView protein in InterPro
IPR000973 CD4
IPR015274 CD4-extracel
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR008424 Ig_C2-set
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR013151 Immunoglobulin
IPR021963 Tcell_CD4_Cterm
PANTHERiPTHR11422:SF0 PTHR11422:SF0, 1 hit
PfamiView protein in Pfam
PF05790 C2-set, 2 hits
PF09191 CD4-extracel, 1 hit
PF00047 ig, 1 hit
PF12104 Tcell_CD4_C, 1 hit
PRINTSiPR00692 CD4TCANTIGEN
SMARTiView protein in SMART
SM00409 IG, 3 hits
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 3 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q3TSV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCRAISLRRL LLLLLQLSQL LAVTQGKTLV LGKEGESAEL PCESSQKKIT
60 70 80 90 100
VFTWKFSDQR KILGQHGKGV LIRGGSPSQF DRFDSKKGAW EKGSFPLIIN
110 120 130 140 150
KLKMEDSQTY ICELENRKEE VELWVFKVTF SPGTSLLQGQ SLTLTLDSNS
160 170 180 190 200
KVSNPLTECK HKKGKVVSGS KVLSMSNLRV QDSDFWNCTV TLDQKKNWFG
210 220 230 240 250
MTLSVLGFQS TAITAYKSEG ESAEFSFPLN FAEENGWGEL MWKAEKDSFF
260 270 280 290 300
QPWISFSIKN KEVSVQKSTK DLKLQLKETL PLTLKIPQVS LQFAGSGNLT
310 320 330 340 350
LTLDKGTLHQ EVNLVVMKVA QLNNTLTCEV MGPTSPKMRL TLKQENQEAR
360 370 380 390 400
VSEEQKVVQV VAPETGLWQC LLSEGDKVKM DSRIQVLSRG VNQTVFLACV
410 420 430 440 450
LGGSFGFLGF LGLCILCCVR CRHQQRQAAR MSQIKRLLSE KKTCQCPHRM

QKSHNLI
Length:457
Mass (Da):51,297
Last modified:October 11, 2005 - v1
Checksum:i1B1DA7527CB00F33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK153966 mRNA Translation: BAE32284.1
AK161775 mRNA Translation: BAE36568.1
CH466523 Genomic DNA Translation: EDK99775.1
RefSeqiNP_038516.1, NM_013488.2
UniGeneiMm.2209

Genome annotation databases

GeneIDi12504
KEGGimmu:12504

Similar proteinsi

Entry informationi

Entry nameiQ3TSV7_MOUSE
AccessioniPrimary (citable) accession number: Q3TSV7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health