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Q3TRX1

- Q3TRX1_MOUSE

UniProt

Q3TRX1 - Q3TRX1_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Ntrk3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. neurotrophin receptor activity Source: Ensembl
    2. protein binding Source: MGI
    3. protein kinase activity Source: InterPro

    GO - Biological processi

    1. activation of MAPK activity Source: Ensembl
    2. activation of protein kinase B activity Source: Ensembl
    3. activation of Ras GTPase activity Source: Ensembl
    4. cellular response to retinoic acid Source: Ensembl
    5. cochlea development Source: Ensembl
    6. lens fiber cell differentiation Source: MGI
    7. mechanoreceptor differentiation Source: MGI
    8. modulation by virus of host transcription Source: Ensembl
    9. negative regulation of astrocyte differentiation Source: Ensembl
    10. negative regulation of cell death Source: Ensembl
    11. negative regulation of protein phosphorylation Source: Ensembl
    12. neuron fate specification Source: Ensembl
    13. neuron migration Source: Ensembl
    14. positive regulation of actin cytoskeleton reorganization Source: Ensembl
    15. positive regulation of axon extension involved in regeneration Source: MGI
    16. positive regulation of cell migration Source: Ensembl
    17. positive regulation of cell proliferation Source: Ensembl
    18. positive regulation of gene expression Source: Ensembl
    19. positive regulation of peptidyl-serine phosphorylation Source: Ensembl
    20. positive regulation of positive chemotaxis Source: Ensembl
    21. protein autophosphorylation Source: Ensembl
    22. response to axon injury Source: Ensembl
    23. response to corticosterone Source: Ensembl
    24. response to ethanol Source: Ensembl
    25. transmembrane receptor protein tyrosine kinase signaling pathway Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Ntrk3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:97385. Ntrk3.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. plasma membrane Source: Ensembl
    3. receptor complex Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiQ3TRX1.
    BgeeiQ3TRX1.
    GenevestigatoriQ3TRX1.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000037909.

    Family & Domainsi

    Phylogenomic databases

    InParanoidiQ3TRX1.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
    [Graphical view]
    PfamiPF07714. Pkinase_Tyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q3TRX1-1 [UniParc]FASTAAdd to Basket

    « Hide

    IECITQGRVL ERPRVCPKEV YDVMLGCWQR EPQQRLNIKE IYKILHALGK   50
    ATPIYLDILG 60
    Length:60
    Mass (Da):7,009
    Last modified:October 11, 2005 - v1
    Checksum:i87271660C9D6828E
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK162419 mRNA. Translation: BAE36905.1.
    UniGeneiMm.33496.
    Mm.421361.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK162419 mRNA. Translation: BAE36905.1 .
    UniGenei Mm.33496.
    Mm.421361.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000037909.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:97385. Ntrk3.

    Phylogenomic databases

    InParanoidi Q3TRX1.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3TRX1.
    Bgeei Q3TRX1.
    Genevestigatori Q3TRX1.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
    [Graphical view ]
    Pfami PF07714. Pkinase_Tyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.

    Entry informationi

    Entry nameiQ3TRX1_MOUSE
    AccessioniPrimary (citable) accession number: Q3TRX1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)