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Protein

Caspase

Gene

Casp9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei275UniRule annotation1
Active sitei325UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPSiC14.010.

Names & Taxonomyi

Protein namesi
Recommended name:
CaspaseUniRule annotation
Gene namesi
Name:Casp9Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1277950. Casp9.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030747.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 92CARDInterPro annotationAdd BLAST92
Domaini197 – 329CASPASE_P20InterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the peptidase C14A family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
HOVERGENiHBG059022.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProiView protein in InterPro
IPR001315. CARD.
IPR033171. Caspase-9.
IPR029030. Caspase-like_dom.
IPR033139. Caspase_cys_AS.
IPR016129. Caspase_his_AS.
IPR011029. DEATH-like_dom.
IPR001309. Pept_C14_p20.
IPR015917. Pept_C14A.
IPR017350. Pept_C14A_CASP1-typ.
PANTHERiPTHR10454:SF173. PTHR10454:SF173. 1 hit.
PfamiView protein in Pfam
PF00619. CARD. 1 hit.
PIRSFiPIRSF038001. Caspase_ICE. 1 hit.
PRINTSiPR00376. IL1BCENZYME.
SMARTiView protein in SMART
SM00114. CARD. 1 hit.
SM00115. CASc. 1 hit.
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF52129. SSF52129. 1 hit.
PROSITEiView protein in PROSITE
PS50209. CARD. 1 hit.
PS01122. CASPASE_CYS. 1 hit.
PS01121. CASPASE_HIS. 1 hit.
PS50208. CASPASE_P20. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TRE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEADRQLLR RCRVRLVSEL QVAELWDALL SRELFTRDMI EDIQQAGSGS
60 70 80 90 100
RRDQARQLVT DLETRGRQAL PLFISCLEDT GQGTLASLLQ SGRQAAKQDP
110 120 130 140 150
EAVKPLDHLV PVVLGPMGLT AKEQRVVKLD PSQPAVGNLT PVVLGPEELW
160 170 180 190 200
PARLKPEVLR PETPRPVDIG SGGAHDVCVP GKIRGHADMA YTLDSDPCGH
210 220 230 240 250
CLIINNVNFC PSSGLGTRTG SNLDRDKLEH RFRWLRFMVE VKNDLTAKKM
260 270 280 290 300
VTALMEMAHR NHRALDCFVV VILSHGCQAS HLQFPGAVYG TDGCSVSIEK
310 320 330
IVNIFNGSGC PSLGGKPKLF FIQACGGGEW PGARWE
Length:336
Mass (Da):36,871
Last modified:October 11, 2005 - v1
Checksum:i718F9B2D66E4F30D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK156500 mRNA. Translation: BAE33734.1.
AK162863 mRNA. Translation: BAE37089.1.
UniGeneiMm.88829.

Genome annotation databases

UCSCiuc008vpg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK156500 mRNA. Translation: BAE33734.1.
AK162863 mRNA. Translation: BAE37089.1.
UniGeneiMm.88829.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030747.

Protein family/group databases

MEROPSiC14.010.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc008vpg.1. mouse.

Organism-specific databases

MGIiMGI:1277950. Casp9.

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
HOVERGENiHBG059022.

Miscellaneous databases

ChiTaRSiCasp9. mouse.
SOURCEiSearch...

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
3.40.50.1460. 1 hit.
InterProiView protein in InterPro
IPR001315. CARD.
IPR033171. Caspase-9.
IPR029030. Caspase-like_dom.
IPR033139. Caspase_cys_AS.
IPR016129. Caspase_his_AS.
IPR011029. DEATH-like_dom.
IPR001309. Pept_C14_p20.
IPR015917. Pept_C14A.
IPR017350. Pept_C14A_CASP1-typ.
PANTHERiPTHR10454:SF173. PTHR10454:SF173. 1 hit.
PfamiView protein in Pfam
PF00619. CARD. 1 hit.
PIRSFiPIRSF038001. Caspase_ICE. 1 hit.
PRINTSiPR00376. IL1BCENZYME.
SMARTiView protein in SMART
SM00114. CARD. 1 hit.
SM00115. CASc. 1 hit.
SUPFAMiSSF47986. SSF47986. 1 hit.
SSF52129. SSF52129. 1 hit.
PROSITEiView protein in PROSITE
PS50209. CARD. 1 hit.
PS01122. CASPASE_CYS. 1 hit.
PS01121. CASPASE_HIS. 1 hit.
PS50208. CASPASE_P20. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3TRE1_MOUSE
AccessioniPrimary (citable) accession number: Q3TRE1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: February 15, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.