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Protein

p2X purinoceptor

Gene

P2rx4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Receptor for ATP that acts as a ligand-gated ion channel.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channelUniRule annotation, ReceptorUniRule annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
p2X purinoceptorUniRule annotation
Gene namesi
Name:P2rx4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1338859. P2rx4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 50HelicalUniRule annotationAdd BLAST21
Transmembranei339 – 361HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL3845.

PTM / Processingi

Proteomic databases

PaxDbiQ3TR36.
PeptideAtlasiQ3TR36.

Expressioni

Gene expression databases

GenevisibleiQ3TR36. MM.

Family & Domainsi

Sequence similaritiesi

Belongs to the P2X receptor family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG410IFJF. Eukaryota.
ENOG410XR0C. LUCA.
HOVERGENiHBG053086.

Family and domain databases

Gene3Di2.60.490.10. 1 hit.
InterProiView protein in InterPro
IPR003047. P2X4_purnocptor.
IPR027309. P2X_extracellular_dom.
IPR001429. P2X_purnocptor.
PANTHERiPTHR10125. PTHR10125. 1 hit.
PfamiView protein in Pfam
PF00864. P2X_receptor. 1 hit.
PIRSFiPIRSF005713. P2X_purinoceptor. 1 hit.
PRINTSiPR01311. P2X4RECEPTOR.
PR01307. P2XRECEPTOR.
TIGRFAMsiTIGR00863. P2X. 1 hit.
PROSITEiView protein in PROSITE
PS01212. P2X_RECEPTOR. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TR36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGCCSVLRA FLFEYDTPRI VLIRSRKVGL MNRVVQLLIL AYVIGWVFVW
60 70 80 90 100
EKGYQETDSV VSSVTTKAKG VAVTNTSQLG FRIWDVADYV VPAQEENSLF
110 120 130 140 150
IMTNMIVTVN QTQGTCPEIP DKTSICDSDA NCTLGSSDTH SSGIGTGRCV
160 170 180 190 200
PFNASVKTCE VAAWCPVEND AGVPTPAFLK AAENFTLLVK NNIWYPKFNF
210 220 230 240 250
SKRNILPNIT TSYLKSCIYN ARTDPFCPIF RLGQIVADAG HSFQEMAVEG
260 270 280 290 300
GIMGIQIKWD CNLDRAASHC LPRYSFRRLD TRDLEHNVSH GYNFRFAKYY
310 320 330 340 350
RDLAGNEQRT LTKAYGIRFD IIVFGKAGKF DIIPTMINVG SGLALLGVAT
360 370 380
VLCDVIVLYC MKKRYYYRDK KYKYVEDYEQ GLSGETDQ
Length:388
Mass (Da):43,532
Last modified:October 11, 2005 - v1
Checksum:iD7AE8DC76086D50D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK163104 mRNA. Translation: BAE37194.1.
UniGeneiMm.290884.
Mm.463383.

Similar proteinsi

Entry informationi

Entry nameiQ3TR36_MOUSE
AccessioniPrimary (citable) accession number: Q3TR36
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 5, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)