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Protein
Submitted name:

Origin recognition complex subunit 6

Gene

Orc6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-176187. Activation of ATR in response to replication stress.
R-MMU-68616. Assembly of the ORC complex at the origin of replication.
R-MMU-68689. CDC6 association with the ORC:origin complex.
R-MMU-68827. CDT1 association with the CDC6:ORC:origin complex.
R-MMU-68867. Assembly of the pre-replicative complex.
R-MMU-68949. Orc1 removal from chromatin.
R-MMU-68962. Activation of the pre-replicative complex.
R-MMU-69300. Removal of licensing factors from origins.

Names & Taxonomyi

Protein namesi
Submitted name:
Origin recognition complex subunit 6Imported
Gene namesi
Name:Orc6Imported
Synonyms:Orc6lImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1929285. Orc6.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000031697.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4557. Eukaryota.
ENOG4111GUY. LUCA.
GeneTreeiENSGT00390000007370.
HOVERGENiHBG007876.
KOiK02608.

Family and domain databases

InterProiView protein in InterPro
IPR020529. ORC6_met/pln.
PANTHERiPTHR13394. PTHR13394. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD315657. Origin_recog_cplx_su6-like. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TQX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVYQSCLKSF ECLLGLNSNV GIRDLAVQFS CTEAVNLAAE ILQSYESGLP
60 70 80 90 100
ETQRADLDLS RPLFTTAALL SACKILKIKV DKTKMITASG VKKAILDRLC
110 120 130 140 150
KQLEKIGQQI NRDSADLARP ALKRKKPEFS PTLKKKEPGL EPPAKEIEVI
160 170 180
ETLHKLPKDE DLTQDYEEWK RKILENAAKA QTATAE
Length:186
Mass (Da):20,741
Last modified:October 11, 2005 - v1
Checksum:i5B1FEC395AF1C532
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134854 Genomic DNA. No translation available.
AK163256 mRNA. Translation: BAE37261.1.
RefSeqiNP_001157263.1. NM_001163791.1.
NP_062690.2. NM_019716.2.
UniGeneiMm.29709.

Genome annotation databases

EnsembliENSMUST00000170141; ENSMUSP00000126925; ENSMUSG00000031697.
GeneIDi56452.
KEGGimmu:56452.
UCSCiuc009mpq.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ3TQX1_MOUSE
AccessioniPrimary (citable) accession number: Q3TQX1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: August 30, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported