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Protein
Submitted name:

Putative uncharacterized protein

Gene

Capn5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium-dependent cysteine-type endopeptidase activity Source: GO_Central

GO - Biological processi

  1. proteolysis Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Capn5Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1100859. Capn5.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: MGI
  2. cytoplasm Source: GO_Central
  3. extracellular vesicular exosome Source: MGI
  4. focal adhesion Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ3TPL4.

Expressioni

Gene expression databases

BgeeiQ3TPL4.
ExpressionAtlasiQ3TPL4. baseline and differential.
GenevestigatoriQ3TPL4.

Structurei

3D structure databases

ProteinModelPortaliQ3TPL4.
SMRiQ3TPL4. Positions 5-490.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118971.
HOVERGENiHBG001095.
KOiK08574.
OMAiPGPTVRW.
PhylomeDBiQ3TPL4.

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
InterProiIPR000008. C2_dom.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR000169. Pept_cys_AS.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PfamiPF00168. C2. 1 hit.
PF01067. Calpain_III. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00239. C2. 1 hit.
SM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 1 hit.
SSF49758. SSF49758. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3TPL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSCAKAYED QNYSALKRAC LRKKVLFEDP LFPATDDSLY YKGTPGPTVR
60 70 80 90 100
WKRPKDICDD PRLFVDGISS HDLHQGQVGN CWFVAACSSL ASRESLWQKV
110 120 130 140 150
IPDWKEQEWN PEKPDSYAGI FHFNFWRFGE WVDVIVDDRL PTVNNQLIYC
160 170 180 190 200
HSNSKNEFWC ALVEKAYAKL AGCYQALDGG NTADALVDFT GGVSEPIDLT
210 220 230 240 250
EGDLATDEAK RNQLFERVLK VHSRGGLISA SIKAVTAADM EARLACGLVK
260 270 280 290 300
GHAYAVTDVR KVRLGHGLLA FFKSEKLDMI RLRNPWGERE WTGPWSDTSE
310 320 330 340 350
EWQKVSKSER EKMGVTVQDD GEFWMTFEDM CRYFTDIIKC RLINTSYLSI
360 370 380 390 400
HKTWEEARLH GAWTRHEDPQ QNRSGGCINH KDTFFQNPQY VFEVKKPEDE
410 420 430 440 450
VLISIQQRPK RSTRREGKGE NLAIGFDIYK VEENRQYRMH SLQHKAASSI
460 470 480 490 500
YINSRSVFLR TELPEGRYVI IPTTFEPGHT GEFLLRVFTD VPSNCRELRL
510 520 530 540 550
DEPPRTCWSS LCGYPQQVAQ VHVLGAAGLK DSPTGANSYV IIKCEGEKVR
560 570 580 590 600
SAVQRGTSTP EYNVKGIFYR KKLAQPITVQ VWNHRVLKDE FLGQVHLKTA
610 620 630 640
PDDLQDLHTL HLQDRSSRQP SDLPGIVAVR VLCSASLTAV
Length:640
Mass (Da):72,955
Last modified:October 11, 2005 - v1
Checksum:i7F1DA3E299FEC02D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK164293 mRNA. Translation: BAE37722.1.
RefSeqiNP_001288179.1. NM_001301250.1.
NP_031628.1. NM_007602.4.
UniGeneiMm.326847.

Genome annotation databases

GeneIDi12337.
KEGGimmu:12337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK164293 mRNA. Translation: BAE37722.1.
RefSeqiNP_001288179.1. NM_001301250.1.
NP_031628.1. NM_007602.4.
UniGeneiMm.326847.

3D structure databases

ProteinModelPortaliQ3TPL4.
SMRiQ3TPL4. Positions 5-490.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ3TPL4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12337.
KEGGimmu:12337.

Organism-specific databases

CTDi726.
MGIiMGI:1100859. Capn5.

Phylogenomic databases

GeneTreeiENSGT00760000118971.
HOVERGENiHBG001095.
KOiK08574.
OMAiPGPTVRW.
PhylomeDBiQ3TPL4.

Miscellaneous databases

ChiTaRSiCapn5. mouse.
NextBioi280956.
SOURCEiSearch...

Gene expression databases

BgeeiQ3TPL4.
ExpressionAtlasiQ3TPL4. baseline and differential.
GenevestigatoriQ3TPL4.

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
InterProiIPR000008. C2_dom.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR000169. Pept_cys_AS.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PfamiPF00168. C2. 1 hit.
PF01067. Calpain_III. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00239. C2. 1 hit.
SM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 1 hit.
SSF49758. SSF49758. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2000)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2004)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.

Entry informationi

Entry nameiQ3TPL4_MOUSE
AccessioniPrimary (citable) accession number: Q3TPL4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: February 4, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.