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Q3TNX8 (Q3TNX8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
A disintegrin and metalloproteinase with thrombospondin motifs 4 Ensembl ENSMUSP00000006570
Gene names
Name:Adamts4 Ensembl ENSMUSP00000006570 MGI 1339949
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length845 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 peptidase M12B domain. SAAS SAAS002870 RuleBase RU004141

Sequences

Sequence LengthMass (Da)Tools
Q3TNX8 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: B496C3190D1A9225

FASTA84591,239
        10         20         30         40         50         60 
MASIHPSCSP GTMSQMGLHP RRGLTGHWLQ RFQPCLPLHT VQWRRLLLLA FLLSLAWPAS 

        70         80         90        100        110        120 
PLPREEEIVF PEKLNGSSIL PGSGVPARLL YRLPAFGEML LLELEQDPGV QVEGLTVQYL 

       130        140        150        160        170        180 
GQAPEMLGGA EPGTYLTGTI NGDPESVASL HWDGGALLGV LQYRGAELHL QPLEGGALNS 

       190        200        210        220        230        240 
AGGPGAHILR RKSPASSQGP MCTVKAPSGS PSPISRRTKR FASLSRFVET LVVADDKMAA 

       250        260        270        280        290        300 
FHGTGLKRYL LTVMAAAAKA FKHPSIRNPV NLVVTRLVIL GSGQEGPQVG PSAAQTLRSF 

       310        320        330        340        350        360 
CTWQRGLNTP NDSDPDHFDT AILFTRQDLC GVSTCDTLGM ADVGTVCDPA RSCAIVEDDG 

       370        380        390        400        410        420 
LQSAFTAAHE LGHVFNMLHD NSKPCTNLNG QGGSSRHVMA PVMAHVDPEE PWSPCSARFI 

       430        440        450        460        470        480 
TDFLDNGYGH CLLDKPEAPL HLPATFPGKD YDADRQCQLT FGPDSSHCPQ LPPPCAALWC 

       490        500        510        520        530        540 
SGHLNGHAMC QTKHSPWADG TPCGSSQACM GGRCLHVDQL KDFNVPQAGG WGPWGPWGDC 

       550        560        570        580        590        600 
SRTCGGGVQF SSRDCTRPVP RNGGKYCEGR RTRFRSCNTE NCPHGSALTF REEQCAAYNH 

       610        620        630        640        650        660 
RTDLFKSFPG PMDWVPRYTG VAPRDQCKLT CQARALGYYY VLEPRVADGT PCSPDTSSVC 

       670        680        690        700        710        720 
VQGRCIHAGC DRIIGSKKKF DKCMVCGGDG SRCSKQSGSF KKFRYGYSDV VTIPAGATHI 

       730        740        750        760        770        780 
LVRQQGGSGL KSIYLALKLS DGSYALNGEY TLMPSPTDVV LPGAVSLRYS GATAASETLS 

       790        800        810        820        830        840 
GHGPLAQPLT LQVLVAGNPQ NARLRYSFFV PRPVPSTPRP PPQDWLQRRA EILKILRKRP 


WAGRK

« Hide

References

« Hide 'large scale' references
[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE37959.1.
Tissue: Lung EMBL BAE37959.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE37959.1.
Tissue: Lung EMBL BAE37959.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE37959.1.
Tissue: Lung EMBL BAE37959.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE37959.1.
Tissue: Lung EMBL BAE37959.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE37959.1.
Tissue: Lung EMBL BAE37959.1.
[6]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE37959.1.
Tissue: Lung EMBL BAE37959.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE37959.1.
Tissue: Lung EMBL BAE37959.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE37959.1.
Tissue: Lung EMBL BAE37959.1.
[9]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000006570.
[10]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000006570.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC084821 Genomic DNA. No translation available.
AK164900 mRNA. Translation: BAE37959.1.
IPIIPI00469188.
RefSeqNP_766433.1. NM_172845.2.
UniGeneMm.23156.

3D structure databases

SMRQ3TNX8. Positions 223-813.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000006570; ENSMUSP00000006570; ENSMUSG00000006403.
GeneID240913.
KEGGmmu:240913.
UCSCuc007dnn.1. mouse.

Organism-specific databases

CTD9507.
MGIMGI:1339949. Adamts4.

Phylogenomic databases

GeneTreeENSGT00650000092972.
HOGENOMHOG000004799.
HOVERGENHBG004313.
InParanoidQ3TNX8.
KOK07764.
OMAHAGCDRI.

Gene expression databases

GenevestigatorQ3TNX8.

Family and domain databases

Gene3D3.40.390.10. 1 hit.
InterProIPR010294. ADAM_spacer1.
IPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
IPR013273. Peptidase_M12B_ADAM-TS.
IPR002870. Peptidase_M12B_N.
IPR000884. Thrombospondin_1_rpt.
[Graphical view]
PfamPF05986. ADAM_spacer1. 1 hit.
PF01562. Pep_M12B_propep. 1 hit.
PF01421. Reprolysin. 1 hit.
PF00090. TSP_1. 1 hit.
[Graphical view]
PRINTSPR01857. ADAMTSFAMILY.
SMARTSM00209. TSP1. 1 hit.
[Graphical view]
SUPFAMSSF82895. TSP1. 1 hit.
PROSITEPS50215. ADAM_MEPRO. 1 hit.
PS50092. TSP1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio384802.
SOURCESearch...

Entry information

Entry nameQ3TNX8_MOUSE
AccessionPrimary (citable) accession number: Q3TNX8
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 3, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info