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Q3TNJ8

- Q3TNJ8_MOUSE

UniProt

Q3TNJ8 - Q3TNJ8_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Pik3cb

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. 1-phosphatidylinositol-3-kinase activity Source: MGI
  2. 1-phosphatidylinositol-4-phosphate 3-kinase activity Source: RefGenome
  3. insulin receptor substrate binding Source: MGI
  4. phosphatidylinositol-4,5-bisphosphate 3-kinase activity Source: RefGenome

GO - Biological processi

  1. cellular calcium ion homeostasis Source: MGI
  2. embryonic cleavage Source: MGI
  3. homophilic cell adhesion via plasma membrane adhesion molecules Source: MGI
  4. phosphatidylinositol-3-phosphate biosynthetic process Source: GOC
  5. phosphatidylinositol-mediated signaling Source: InterPro
  6. platelet activation Source: MGI
  7. regulation of cell-matrix adhesion Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Pik3cbImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1922019. Pik3cb.

Subcellular locationi

GO - Cellular componenti

  1. phosphatidylinositol 3-kinase complex Source: RefGenome
  2. plasma membrane Source: RefGenome
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ3TNJ8.
ExpressionAtlasiQ3TNJ8. baseline and differential.
GenevestigatoriQ3TNJ8.

Family & Domainsi

Sequence similaritiesi

Contains PI3K/PI4K domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG052721.

Family and domain databases

Gene3Di1.10.1070.11. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR000403. PI3/4_kinase_cat_dom.
IPR018936. PI3/4_kinase_CS.
IPR015433. PI_Kinase.
[Graphical view]
PANTHERiPTHR10048. PTHR10048. 1 hit.
PfamiPF00454. PI3_PI4_kinase. 1 hit.
[Graphical view]
SMARTiSM00146. PI3Kc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3TNJ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GKEAMHTCLK QSAYREALSD LQSPLNPCVI LSELYVEKCK YMDSKMKPLW
60 70 80 90 100
LVYSSRAFGE DSVGVIFKNG DDLRQDMLTL QMLRLMDLLW KEAGLDLRML
110 120 130 140 150
PYGCLATGDR SGLIEVVSTS ETIADIQLNS SNVAATAAFN KDALLNWLKE
160 170 180 190 200
YNSGDDLDRA IEEFTLSCAG YCVASYVLGI GDRHSDNIMV KKTGQLFHID
210 220 230 240 250
FGHILGNFKS KFGIKRERVP FILTYDFIHV IQQGKTGNTE KFGRFRQCCE
260 270 280 290 300
DAYLILRRHG NLFITLFALM LTAGLPELTS VKDIQYLKDS LALGKSEEEA
310 320 330
LKQFKQKFDE ALRESWTTKV NWMAHTVRKD YRS
Length:333
Mass (Da):37,854
Last modified:October 11, 2005 - v1
Checksum:iB4D9D96A420C8B19
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK165230 mRNA. Translation: BAE38090.1.
UniGeneiMm.213128.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK165230 mRNA. Translation: BAE38090.1 .
UniGenei Mm.213128.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1922019. Pik3cb.

Phylogenomic databases

HOVERGENi HBG052721.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q3TNJ8.
ExpressionAtlasi Q3TNJ8. baseline and differential.
Genevestigatori Q3TNJ8.

Family and domain databases

Gene3Di 1.10.1070.11. 1 hit.
InterProi IPR011009. Kinase-like_dom.
IPR000403. PI3/4_kinase_cat_dom.
IPR018936. PI3/4_kinase_CS.
IPR015433. PI_Kinase.
[Graphical view ]
PANTHERi PTHR10048. PTHR10048. 1 hit.
Pfami PF00454. PI3_PI4_kinase. 1 hit.
[Graphical view ]
SMARTi SM00146. PI3Kc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SpleenImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SpleenImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SpleenImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SpleenImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SpleenImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SpleenImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SpleenImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: SpleenImported.

Entry informationi

Entry nameiQ3TNJ8_MOUSE
AccessioniPrimary (citable) accession number: Q3TNJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 26, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)