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Q3TNJ8

- Q3TNJ8_MOUSE

UniProt

Q3TNJ8 - Q3TNJ8_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Pik3cb

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 1-phosphatidylinositol-3-kinase activity Source: MGI
    2. 1-phosphatidylinositol-4-phosphate 3-kinase activity Source: RefGenome
    3. insulin receptor substrate binding Source: MGI
    4. phosphatidylinositol-4,5-bisphosphate 3-kinase activity Source: RefGenome

    GO - Biological processi

    1. cellular calcium ion homeostasis Source: MGI
    2. embryonic cleavage Source: MGI
    3. homophilic cell adhesion Source: MGI
    4. phosphatidylinositol-3-phosphate biosynthetic process Source: GOC
    5. phosphatidylinositol-mediated signaling Source: InterPro
    6. platelet activation Source: MGI
    7. regulation of cell-matrix adhesion Source: MGI

    Keywords - Molecular functioni

    KinaseSAAS annotation, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Pik3cbImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1922019. Pik3cb.

    Subcellular locationi

    GO - Cellular componenti

    1. phosphatidylinositol 3-kinase complex Source: RefGenome
    2. plasma membrane Source: RefGenome

    Expressioni

    Gene expression databases

    ArrayExpressiQ3TNJ8.
    BgeeiQ3TNJ8.
    GenevestigatoriQ3TNJ8.

    Family & Domainsi

    Sequence similaritiesi

    Contains PI3K/PI4K domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG052721.
    InParanoidiQ3TNJ8.

    Family and domain databases

    Gene3Di1.10.1070.11. 1 hit.
    InterProiIPR011009. Kinase-like_dom.
    IPR000403. PI3/4_kinase_cat_dom.
    IPR018936. PI3/4_kinase_CS.
    IPR015433. PI_Kinase.
    [Graphical view]
    PANTHERiPTHR10048. PTHR10048. 1 hit.
    PfamiPF00454. PI3_PI4_kinase. 1 hit.
    [Graphical view]
    SMARTiSM00146. PI3Kc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00915. PI3_4_KINASE_1. 1 hit.
    PS00916. PI3_4_KINASE_2. 1 hit.
    PS50290. PI3_4_KINASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3TNJ8-1 [UniParc]FASTAAdd to Basket

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    GKEAMHTCLK QSAYREALSD LQSPLNPCVI LSELYVEKCK YMDSKMKPLW    50
    LVYSSRAFGE DSVGVIFKNG DDLRQDMLTL QMLRLMDLLW KEAGLDLRML 100
    PYGCLATGDR SGLIEVVSTS ETIADIQLNS SNVAATAAFN KDALLNWLKE 150
    YNSGDDLDRA IEEFTLSCAG YCVASYVLGI GDRHSDNIMV KKTGQLFHID 200
    FGHILGNFKS KFGIKRERVP FILTYDFIHV IQQGKTGNTE KFGRFRQCCE 250
    DAYLILRRHG NLFITLFALM LTAGLPELTS VKDIQYLKDS LALGKSEEEA 300
    LKQFKQKFDE ALRESWTTKV NWMAHTVRKD YRS 333
    Length:333
    Mass (Da):37,854
    Last modified:October 11, 2005 - v1
    Checksum:iB4D9D96A420C8B19
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK165230 mRNA. Translation: BAE38090.1.
    UniGeneiMm.213128.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK165230 mRNA. Translation: BAE38090.1 .
    UniGenei Mm.213128.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1922019. Pik3cb.

    Phylogenomic databases

    HOVERGENi HBG052721.
    InParanoidi Q3TNJ8.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3TNJ8.
    Bgeei Q3TNJ8.
    Genevestigatori Q3TNJ8.

    Family and domain databases

    Gene3Di 1.10.1070.11. 1 hit.
    InterProi IPR011009. Kinase-like_dom.
    IPR000403. PI3/4_kinase_cat_dom.
    IPR018936. PI3/4_kinase_CS.
    IPR015433. PI_Kinase.
    [Graphical view ]
    PANTHERi PTHR10048. PTHR10048. 1 hit.
    Pfami PF00454. PI3_PI4_kinase. 1 hit.
    [Graphical view ]
    SMARTi SM00146. PI3Kc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00915. PI3_4_KINASE_1. 1 hit.
    PS00916. PI3_4_KINASE_2. 1 hit.
    PS50290. PI3_4_KINASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SpleenImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SpleenImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SpleenImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SpleenImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SpleenImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SpleenImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SpleenImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: SpleenImported.

    Entry informationi

    Entry nameiQ3TNJ8_MOUSE
    AccessioniPrimary (citable) accession number: Q3TNJ8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)