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Protein
Submitted name:

ATP-sensitive inward rectifier potassium channel 15

Gene

Kcnj15

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei184 – 1841Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesiumUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Voltage-gated channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transportUniRule annotationSAAS annotation, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-sensitive inward rectifier potassium channel 15Imported
Submitted name:
Potassium inwardly-rectifying channel, subfamily J, member 15Imported
Gene namesi
Name:Kcnj15Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1310000. Kcnj15.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei94 – 11522HelicalSequence analysisAdd
BLAST
Transmembranei169 – 19325HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000062609.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045218.

Family & Domainsi

Sequence similaritiesi

Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3827. Eukaryota.
ENOG410XQ62. LUCA.
GeneTreeiENSGT00760000118842.
HOVERGENiHBG006178.
OMAiCPLAIFT.
OrthoDBiEOG091G08HC.
TreeFamiTF313676.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR003270. K_chnl_inward-rec_Kir1.3.
IPR013518. K_chnl_inward-rec_Kir_cyto.
[Graphical view]
PANTHERiPTHR11767. PTHR11767. 1 hit.
PTHR11767:SF20. PTHR11767:SF20. 1 hit.
PfamiPF01007. IRK. 1 hit.
[Graphical view]
PIRSFiPIRSF005465. GIRK_kir. 1 hit.
PRINTSiPR01323. KIR13CHANNEL.
PR01320. KIRCHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TNE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVARWEKGSE DAPLTLQKIP DLQSGPKMDA IHLGMSSAPL VKHTNGVGLK
60 70 80 90 100
AHRPRVMSKS GHSNVRIDKV DGIYLLYLQD LWTTVIDMKW RYKLTLFAAT
110 120 130 140 150
FVMTWFLFGV VYYAIAFIHG DLQLGESNSN HTPCIMKVDS LTGAFLFSLE
160 170 180 190 200
SQTTIGYGVR SITEECPHAI FLLVAQLVIT TLIEIFITGT FLAKIARPKK
210 220 230 240 250
RAETIKFSHC AVISKQNGKL CLVIQVANMR KSLLIQCQLS GKLLQTHVTK
260 270 280 290 300
EGERILLNQA TVKFHVDSSS ESPFLILPMT FYHVLDETSP LRDLTPQNLK
310 320 330 340 350
EKEFELVVLL NATVESTSAV CQSRTSYIPE EIYWGFEFVP VVSLSKNGKY
360 370 380 390 400
VADFSQFEQI RKSPDCTFYC ADSEKQKLEE QYRQEDQRER ELRSLLLQQS

NV
Length:402
Mass (Da):45,583
Last modified:October 11, 2005 - v1
Checksum:iEABD9F35622A83D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154546 Genomic DNA. No translation available.
AC154691 Genomic DNA. No translation available.
BC138477 mRNA. Translation: AAI38478.1.
AK165346 mRNA. Translation: BAE38143.1.
RefSeqiNP_001034146.1. NM_001039057.2.
NP_001258616.1. NM_001271687.1.
NP_001258619.1. NM_001271690.1.
NP_001258621.1. NM_001271692.1.
NP_001258623.1. NM_001271694.1.
XP_006523005.1. XM_006522942.2.
XP_006523007.1. XM_006522944.2.
XP_006523008.1. XM_006522945.2.
XP_006523009.1. XM_006522946.2.
XP_006523010.1. XM_006522947.2.
XP_006523012.1. XM_006522949.2.
XP_006523236.1. XM_006523173.2.
XP_006523237.1. XM_006523174.2.
XP_006523238.1. XM_006523175.2.
XP_006523239.1. XM_006523176.2.
XP_006523240.1. XM_006523177.2.
XP_006523241.1. XM_006523178.2.
XP_006523242.1. XM_006523179.2.
XP_006523243.1. XM_006523180.2.
XP_006523244.1. XM_006523181.2.
XP_006523245.1. XM_006523182.2.
XP_006523247.1. XM_006523184.2.
UniGeneiMm.272239.
Mm.491313.

Genome annotation databases

EnsembliENSMUST00000037154; ENSMUSP00000045218; ENSMUSG00000062609.
ENSMUST00000113858; ENSMUSP00000109489; ENSMUSG00000062609.
ENSMUST00000113859; ENSMUSP00000109490; ENSMUSG00000062609.
ENSMUST00000113861; ENSMUSP00000109492; ENSMUSG00000062609.
ENSMUST00000113862; ENSMUSP00000109493; ENSMUSG00000062609.
GeneIDi16516.
UCSCiuc008abu.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154546 Genomic DNA. No translation available.
AC154691 Genomic DNA. No translation available.
BC138477 mRNA. Translation: AAI38478.1.
AK165346 mRNA. Translation: BAE38143.1.
RefSeqiNP_001034146.1. NM_001039057.2.
NP_001258616.1. NM_001271687.1.
NP_001258619.1. NM_001271690.1.
NP_001258621.1. NM_001271692.1.
NP_001258623.1. NM_001271694.1.
XP_006523005.1. XM_006522942.2.
XP_006523007.1. XM_006522944.2.
XP_006523008.1. XM_006522945.2.
XP_006523009.1. XM_006522946.2.
XP_006523010.1. XM_006522947.2.
XP_006523012.1. XM_006522949.2.
XP_006523236.1. XM_006523173.2.
XP_006523237.1. XM_006523174.2.
XP_006523238.1. XM_006523175.2.
XP_006523239.1. XM_006523176.2.
XP_006523240.1. XM_006523177.2.
XP_006523241.1. XM_006523178.2.
XP_006523242.1. XM_006523179.2.
XP_006523243.1. XM_006523180.2.
XP_006523244.1. XM_006523181.2.
XP_006523245.1. XM_006523182.2.
XP_006523247.1. XM_006523184.2.
UniGeneiMm.272239.
Mm.491313.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045218.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000037154; ENSMUSP00000045218; ENSMUSG00000062609.
ENSMUST00000113858; ENSMUSP00000109489; ENSMUSG00000062609.
ENSMUST00000113859; ENSMUSP00000109490; ENSMUSG00000062609.
ENSMUST00000113861; ENSMUSP00000109492; ENSMUSG00000062609.
ENSMUST00000113862; ENSMUSP00000109493; ENSMUSG00000062609.
GeneIDi16516.
UCSCiuc008abu.2. mouse.

Organism-specific databases

CTDi3772.
MGIiMGI:1310000. Kcnj15.

Phylogenomic databases

eggNOGiKOG3827. Eukaryota.
ENOG410XQ62. LUCA.
GeneTreeiENSGT00760000118842.
HOVERGENiHBG006178.
OMAiCPLAIFT.
OrthoDBiEOG091G08HC.
TreeFamiTF313676.

Miscellaneous databases

ChiTaRSiKcnj15. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000062609.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR003270. K_chnl_inward-rec_Kir1.3.
IPR013518. K_chnl_inward-rec_Kir_cyto.
[Graphical view]
PANTHERiPTHR11767. PTHR11767. 1 hit.
PTHR11767:SF20. PTHR11767:SF20. 1 hit.
PfamiPF01007. IRK. 1 hit.
[Graphical view]
PIRSFiPIRSF005465. GIRK_kir. 1 hit.
PRINTSiPR01323. KIR13CHANNEL.
PR01320. KIRCHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3TNE6_MOUSE
AccessioniPrimary (citable) accession number: Q3TNE6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.