ID   XYLB_MOUSE              Reviewed;         551 AA.
AC   Q3TNA1; Q8R156;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   16-JUN-2009, entry version 30.
DE   RecName: Full=Xylulose kinase;
DE            Short=Xylulokinase;
DE            EC=2.7.1.17;
GN   Name=Xylb;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Kidney;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
RA   Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
RA   Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
RA   Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
RA   Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
RA   Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
RA   di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
RA   Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
RA   Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
RA   Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
RA   Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
RA   Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
RA   Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
RA   Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
RA   Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
RA   Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
RA   Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
RA   Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
RA   Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
RA   Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
RA   Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
RA   Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
RA   Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
RA   Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
RA   Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
RA   Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
RA   Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
RA   Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
RA   Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
RA   Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
RA   Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
RA   Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 13-551.
RC   STRAIN=FVB/N; TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- CATALYTIC ACTIVITY: ATP + D-xylulose = ADP + D-xylulose 5-
CC       phosphate.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
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DR   EMBL; AK143476; BAE25393.1; -; mRNA.
DR   EMBL; AK165440; BAE38188.1; -; mRNA.
DR   EMBL; AK165518; BAE38233.1; -; mRNA.
DR   EMBL; BC025442; AAH25442.1; ALT_INIT; mRNA.
DR   IPI; IPI00153294; -.
DR   RefSeq; NP_001028381.1; -.
DR   UniGene; Mm.219497; -.
DR   Ensembl; ENSMUSG00000035769; Mus musculus.
DR   GeneID; 102448; -.
DR   KEGG; mmu:102448; -.
DR   MGI; MGI:2142985; Xylb.
DR   HOGENOM; Q3TNA1; -.
DR   HOVERGEN; Q3TNA1; -.
DR   OMA; Q3TNA1; FSTQQLK.
DR   BRENDA; 2.7.1.17; 244.
DR   NextBio; 355490; -.
DR   ArrayExpress; Q3TNA1; -.
DR   Bgee; Q3TNA1; -.
DR   CleanEx; MM_XYLB; -.
DR   GermOnline; ENSMUSG00000035769; Mus musculus.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004856; F:xylulokinase activity; IEA:EC.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   PANTHER; PTHR10196; FGGY_kin; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Carbohydrate metabolism; Kinase; Nucleotide-binding;
KW   Transferase; Xylose metabolism.
FT   CHAIN         1    551       Xylulose kinase.
FT                                /FTId=PRO_0000230986.
SQ   SEQUENCE   551 AA;  59544 MW;  CED895069FBFD97B CRC64;
     MDARTHRRAA GTPRALAERA GRRCCLGWDF STQQVKVVAV DAELNVFYED SVHFDRDLPE
     FGTQGGVHVH KDRLTVTSPV LMWVQALDLI LGKMKSSGFD FSQVLALSGA GQQHGSVYWK
     TGASLALSSL SPALPLHQQL QSCFSISDCP IWMDSSTTAQ CHQLEAAVGG AQALSCLTGS
     RAYERFTGNQ IAKLFQKNPE AYSHSERISL VSSFAASLFL GGYSPIDYSD GSGMNLLQIQ
     EKVWSQACLD VCAPHLEEKL GSPVPSCSVV GTISSYYVQR YGFPPGCKVV AFSGDNPASL
     AGMRLEEGDI AVSLGTSDTL FLWLQKPMPA LEGHIFCNPV DPQHYMALLC FKNGSLMREK
     IRDESASCSW NKFSKALKST AMGNNGNLGF YFDVMEITPE IIGRHRFNAE NMEVSAFPGD
     VEIRALIEGQ FMAKRIHAEG LGYRVMPKTK ILATGGASHN KDILQVLADV FGAPVYVIDT
     TSSACVGSAY RAFHGLAGGT GVAFSEVVKS APQPSLAATP NPGASQVYAA LLPRYSALEQ
     RILSTAQRPL E
//