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Q3TM63

- Q3TM63_MOUSE

UniProt

Q3TM63 - Q3TM63_MOUSE

Protein

Sodium/hydrogen exchanger

Gene

Slc9a2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sodium:proton antiporter activity Source: MGI

    GO - Biological processi

    1. protein localization Source: MGI
    2. regulation of pH Source: MGI
    3. sodium ion transmembrane transport Source: GOC
    4. sodium ion transport Source: MGI

    Keywords - Biological processi

    AntiportUniRule annotationSAAS annotation, Ion transport, Sodium transportUniRule annotation, Transport

    Keywords - Ligandi

    Sodium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Sodium/hydrogen exchangerUniRule annotation
    Gene namesi
    Name:Slc9a2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:105075. Slc9a2.

    Subcellular locationi

    GO - Cellular componenti

    1. brush border Source: MGI
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Proteomic databases

    PaxDbiQ3TM63.

    Expressioni

    Gene expression databases

    BgeeiQ3TM63.
    GenevestigatoriQ3TM63.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3TM63.
    SMRiQ3TM63. Positions 137-162, 231-256.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. [View classification]UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    eggNOGiCOG0025.
    HOVERGENiHBG084586.
    InParanoidiQ3TM63.

    Family and domain databases

    InterProiIPR006153. Cation/H_exchanger.
    IPR018422. Cation/H_exchanger_CPA1.
    IPR004709. NaH_exchanger.
    [Graphical view]
    PANTHERiPTHR10110. PTHR10110. 1 hit.
    PfamiPF00999. Na_H_Exchanger. 1 hit.
    [Graphical view]
    PRINTSiPR01084. NAHEXCHNGR.
    TIGRFAMsiTIGR00840. b_cpa1. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3TM63-1 [UniParc]FASTAAdd to Basket

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    MGPRGTAHSV RAPLSWLLLL LLSLQVAVPA GALAETLLDA PRARGASSNP    50
    PSPASVVAPG TTPFEESRLP VFTLDYPHVQ IPFEITLWIL LASLAKIGFH 100
    LYHKLPTIVP ESCLLIMVGL LLGGIIFGVD EKSPPAMKTD VFFLYLLPPI 150
    VLDAGYFMPT RPFFENFGTI FWYAVVGTLW NSIGIGVSLF GICQIEAFGL 200
    SDITLLQNLL FGSLISAVDP VAVLAVFENI HVNEQLYILV FGESLLNDAV 250
    TVVLYNLFKS FCQMKTIQTV DVFAGIANFF VVGIGGVLIG ILLGFIAAFT 300
    TRFTHNIRVI EPLFVFLYSY LSYITAEMFH LSGIMA 336
    Length:336
    Mass (Da):36,662
    Last modified:October 11, 2005 - v1
    Checksum:i55C1DC0901B79BB4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK166114 mRNA. Translation: BAE38579.1.
    UniGeneiMm.256414.

    Genome annotation databases

    UCSCiuc007aum.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK166114 mRNA. Translation: BAE38579.1 .
    UniGenei Mm.256414.

    3D structure databases

    ProteinModelPortali Q3TM63.
    SMRi Q3TM63. Positions 137-162, 231-256.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q3TM63.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc007aum.1. mouse.

    Organism-specific databases

    MGIi MGI:105075. Slc9a2.

    Phylogenomic databases

    eggNOGi COG0025.
    HOVERGENi HBG084586.
    InParanoidi Q3TM63.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Bgeei Q3TM63.
    Genevestigatori Q3TM63.

    Family and domain databases

    InterProi IPR006153. Cation/H_exchanger.
    IPR018422. Cation/H_exchanger_CPA1.
    IPR004709. NaH_exchanger.
    [Graphical view ]
    PANTHERi PTHR10110. PTHR10110. 1 hit.
    Pfami PF00999. Na_H_Exchanger. 1 hit.
    [Graphical view ]
    PRINTSi PR01084. NAHEXCHNGR.
    TIGRFAMsi TIGR00840. b_cpa1. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.

    Entry informationi

    Entry nameiQ3TM63_MOUSE
    AccessioniPrimary (citable) accession number: Q3TM63
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)