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Q3TM63

- Q3TM63_MOUSE

UniProt

Q3TM63 - Q3TM63_MOUSE

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Protein

Sodium/hydrogen exchanger

Gene

Slc9a2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sodium:proton antiporter activity Source: MGI

GO - Biological processi

  1. protein localization Source: MGI
  2. regulation of pH Source: MGI
  3. sodium ion transmembrane transport Source: GOC
  4. sodium ion transport Source: MGI
Complete GO annotation...

Keywords - Biological processi

AntiportUniRule annotationSAAS annotation, Ion transport, Sodium transportUniRule annotation, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/hydrogen exchangerUniRule annotation
Gene namesi
Name:Slc9a2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:105075. Slc9a2.

Subcellular locationi

GO - Cellular componenti

  1. brush border Source: MGI
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ3TM63.

Expressioni

Gene expression databases

BgeeiQ3TM63.
ExpressionAtlasiQ3TM63. baseline and differential.
GenevestigatoriQ3TM63.

Structurei

3D structure databases

ProteinModelPortaliQ3TM63.
SMRiQ3TM63. Positions 137-162, 231-256.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. [View classification]UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

eggNOGiCOG0025.
HOVERGENiHBG084586.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 1 hit.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSiPR01084. NAHEXCHNGR.
TIGRFAMsiTIGR00840. b_cpa1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TM63-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGPRGTAHSV RAPLSWLLLL LLSLQVAVPA GALAETLLDA PRARGASSNP
60 70 80 90 100
PSPASVVAPG TTPFEESRLP VFTLDYPHVQ IPFEITLWIL LASLAKIGFH
110 120 130 140 150
LYHKLPTIVP ESCLLIMVGL LLGGIIFGVD EKSPPAMKTD VFFLYLLPPI
160 170 180 190 200
VLDAGYFMPT RPFFENFGTI FWYAVVGTLW NSIGIGVSLF GICQIEAFGL
210 220 230 240 250
SDITLLQNLL FGSLISAVDP VAVLAVFENI HVNEQLYILV FGESLLNDAV
260 270 280 290 300
TVVLYNLFKS FCQMKTIQTV DVFAGIANFF VVGIGGVLIG ILLGFIAAFT
310 320 330
TRFTHNIRVI EPLFVFLYSY LSYITAEMFH LSGIMA
Length:336
Mass (Da):36,662
Last modified:October 11, 2005 - v1
Checksum:i55C1DC0901B79BB4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK166114 mRNA. Translation: BAE38579.1.
UniGeneiMm.256414.

Genome annotation databases

UCSCiuc007aum.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK166114 mRNA. Translation: BAE38579.1 .
UniGenei Mm.256414.

3D structure databases

ProteinModelPortali Q3TM63.
SMRi Q3TM63. Positions 137-162, 231-256.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q3TM63.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc007aum.1. mouse.

Organism-specific databases

MGIi MGI:105075. Slc9a2.

Phylogenomic databases

eggNOGi COG0025.
HOVERGENi HBG084586.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q3TM63.
ExpressionAtlasi Q3TM63. baseline and differential.
Genevestigatori Q3TM63.

Family and domain databases

InterProi IPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR004709. NaH_exchanger.
[Graphical view ]
PANTHERi PTHR10110. PTHR10110. 1 hit.
Pfami PF00999. Na_H_Exchanger. 1 hit.
[Graphical view ]
PRINTSi PR01084. NAHEXCHNGR.
TIGRFAMsi TIGR00840. b_cpa1. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.

Entry informationi

Entry nameiQ3TM63_MOUSE
AccessioniPrimary (citable) accession number: Q3TM63
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)