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Protein
Submitted name:

Uncharacterized protein

Gene

Smpdl3b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 2 Zn2+ per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi28Zinc 1UniRule annotation1
Metal bindingi30Zinc 1UniRule annotation1
Metal bindingi93Zinc 1UniRule annotation1
Metal bindingi93Zinc 2UniRule annotation1
Metal bindingi134Zinc 2UniRule annotation1
Metal bindingi236Zinc 2UniRule annotation1
Metal bindingi277Zinc 2UniRule annotation1
Metal bindingi279Zinc 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Smpdl3bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1916022. Smpdl3b.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501109881519 – 456Sequence analysisAdd BLAST438

Proteomic databases

MaxQBiQ3TLX9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000028885.

Structurei

3D structure databases

SMRiQ3TLX9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 280MetallophosInterPro annotationAdd BLAST259

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410ISVB. Eukaryota.
ENOG410XRWF. LUCA.
HOVERGENiHBG050594.
KOiK01128.
OMAiDPLQVCP.
OrthoDBiEOG091G080M.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiView protein in InterPro
IPR017064. ASM-like_Pdiesterase_prd.
IPR004843. Calcineurin-like_PHP_ApaH.
IPR029052. Metallo-depent_PP-like.
PfamiView protein in Pfam
PF00149. Metallophos. 1 hit.
PIRSFiPIRSF036767. ASM-like_PDE. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TLX9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLLGWLIFL APWGVAGAQL GRFWHISDLH LDPNYTVSKD PLQVCPSAGS
60 70 80 90 100
QPVLNAGPWG DYLCDSPWAL INSSLYAMKE IEPKPDFILW TGDDTPHVPN
110 120 130 140 150
ESLGEAAVLA IVERLTNLIK EVFPDTKVYA ALGNHDFHPK NQFPAQSNRI
160 170 180 190 200
YNQVAELWRP WLSNESYALF KRGAFYSEKL PGPSRAGRVV VLNTNLYYSN
210 220 230 240 250
NEQTAGMADP GEQFRWLGDV LSNASRDGEM VYVIGHVPPG FFEKTQNKAW
260 270 280 290 300
FRESFNEEYL KVIQKHHRVI AGQFFGHHHT DSFRMFYDNT GAPINVMFLT
310 320 330 340 350
PGVTPWKTTL PGVVDGANNP GIRIFEYDRA TLNLKDLVTY FLNLRQANVQ
360 370 380 390 400
ETPRWEQEYR LTEAYQVPDA SVSSMHTALT RIASEPHILQ RYYVYNSVSY
410 420 430 440 450
NHLTCEDSCR IEHVCAIQHV AFNTYATCLH GLGAKLVPGF LLILTLLPSL

HVLEVL
Length:456
Mass (Da):51,600
Last modified:October 11, 2005 - v1
Checksum:i11BD6AF4806FD990
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK154599 mRNA. Translation: BAE32702.1.
AK166253 mRNA. Translation: BAE38663.1.
RefSeqiNP_598649.1. NM_133888.2.
UniGeneiMm.287187.

Genome annotation databases

GeneIDi100340.
KEGGimmu:100340.

Similar proteinsi

Entry informationi

Entry nameiQ3TLX9_MOUSE
AccessioniPrimary (citable) accession number: Q3TLX9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 22, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)