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Protein

Microtubule-associated protein

Gene

Map2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Microtubule-associated proteinUniRule annotation
Gene namesi
Name:Map2Imported
Synonyms:Mtap2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:97175. Map2.

Subcellular locationi

  • Cytoplasmcytoskeleton UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotation

PTM / Processingi

Proteomic databases

MaxQBiQ3TLQ0.

PTM databases

iPTMnetiQ3TLQ0.

Expressioni

Gene expression databases

ExpressionAtlasiQ3TLQ0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109650.

Structurei

3D structure databases

SMRiQ3TLQ0. Positions 324-396.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 4 Tau/MAP repeats.UniRule annotation

Keywords - Domaini

RepeatUniRule annotation

Phylogenomic databases

eggNOGiKOG2418. Eukaryota.
ENOG4111J07. LUCA.
GeneTreeiENSGT00530000063491.
HOVERGENiHBG000991.

Family and domain databases

InterProiIPR030797. MAP2.
IPR027324. MAP2/MAP4/Tau.
IPR001084. MAP_tubulin-bd_rpt.
[Graphical view]
PANTHERiPTHR11501. PTHR11501. 1 hit.
PTHR11501:SF15. PTHR11501:SF15. 1 hit.
PfamiPF00418. Tubulin-binding. 4 hits.
[Graphical view]
PROSITEiPS00229. TAU_MAP_1. 3 hits.
PS51491. TAU_MAP_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3TLQ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADERKDEGK APHWTSASLT EAAAHPHSPE MKDQGGAGEG LSRNANGFPY
60 70 80 90 100
REEEEGAFGE HRSQGTYSDT KENGINGELT SADRETAEEV SARIVQVVTA
110 120 130 140 150
EAVAVLKGEQ EKEAQHKDQP AALPLAAEET ANLPPSPPPS PASEQTATVE
160 170 180 190 200
EAASGDLAQA PGAFKQAKDK VTDGISKSPE KRSSLPRPSS ILPPRRGVSG
210 220 230 240 250
DREENSFSLN SSISSARRTT RSEPIRRAGK SGTSTPTTPG STAITPGTPP
260 270 280 290 300
SYSSRTPGTP GTPSYPRTPG TPKSGILVPS EKKVAIIRTP PKSPATPKQL
310 320 330 340 350
RLINQPLPDL KNVKSKIGST DNIKYQPKGG QVRILNKKID FSKVQSRCGS
360 370 380 390 400
KDNIKHSAGG GNVQIVTKKI DLSHVTSKCG SLKNIRHRPG GGRVKIESVK
410 420 430 440 450
LDFKEKAQAK VGSLDNAHHV PGGGNVKIDS QKLNFREHAK ARVDHGAEII
460 470 480 490
TQSPSRSSVA SPRRLSNVSS SGSINLLESP QLATLAEDVT AALAKQGL
Length:498
Mass (Da):52,676
Last modified:October 11, 2005 - v1
Checksum:iE2B03206CF6D2FA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091465 Genomic DNA. No translation available.
AC114403 Genomic DNA. No translation available.
AK166380 mRNA. Translation: BAE38742.1.
RefSeqiNP_001035023.1. NM_001039934.1.
XP_006495822.1. XM_006495759.2.
XP_006495823.1. XM_006495760.1.
UniGeneiMm.256966.
Mm.436793.

Genome annotation databases

EnsembliENSMUST00000114017; ENSMUSP00000109650; ENSMUSG00000015222.
ENSMUST00000114018; ENSMUSP00000109651; ENSMUSG00000015222.
GeneIDi17756.
UCSCiuc007bhw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091465 Genomic DNA. No translation available.
AC114403 Genomic DNA. No translation available.
AK166380 mRNA. Translation: BAE38742.1.
RefSeqiNP_001035023.1. NM_001039934.1.
XP_006495822.1. XM_006495759.2.
XP_006495823.1. XM_006495760.1.
UniGeneiMm.256966.
Mm.436793.

3D structure databases

SMRiQ3TLQ0. Positions 324-396.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109650.

PTM databases

iPTMnetiQ3TLQ0.

Proteomic databases

MaxQBiQ3TLQ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000114017; ENSMUSP00000109650; ENSMUSG00000015222.
ENSMUST00000114018; ENSMUSP00000109651; ENSMUSG00000015222.
GeneIDi17756.
UCSCiuc007bhw.1. mouse.

Organism-specific databases

CTDi4133.
MGIiMGI:97175. Map2.

Phylogenomic databases

eggNOGiKOG2418. Eukaryota.
ENOG4111J07. LUCA.
GeneTreeiENSGT00530000063491.
HOVERGENiHBG000991.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

ExpressionAtlasiQ3TLQ0. baseline and differential.

Family and domain databases

InterProiIPR030797. MAP2.
IPR027324. MAP2/MAP4/Tau.
IPR001084. MAP_tubulin-bd_rpt.
[Graphical view]
PANTHERiPTHR11501. PTHR11501. 1 hit.
PTHR11501:SF15. PTHR11501:SF15. 1 hit.
PfamiPF00418. Tubulin-binding. 4 hits.
[Graphical view]
PROSITEiPS00229. TAU_MAP_1. 3 hits.
PS51491. TAU_MAP_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Mammary glandImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Mammary glandImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Mammary glandImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Mammary glandImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Mammary glandImported.
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Mammary glandImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Mammary glandImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Mammary glandImported.
  10. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
    Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
    Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3TLQ0_MOUSE
AccessioniPrimary (citable) accession number: Q3TLQ0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 8, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.