Fbp2

Functionⁱ

GO - Molecular functionⁱ

fructose 1,6-bisphosphate 1-phosphatase activity Source: Ensembl
identical protein binding Source: Ensembl

GO - Biological processⁱ

gluconeogenesis Source: Ensembl

Keywordsⁱ

Molecular function	HydrolaseUniRule annotation
Biological process	Carbohydrate metabolismUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Fructose bisphosphatase 2Imported Submitted name: Putative uncharacterized proteinImported
Gene namesⁱ	Name:Fbp2Imported ORF Names:mCG_22016Imported
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:95491. Fbp2.

Subcellular locationⁱ

GO - Cellular componentⁱ

extracellular exosome Source: Ensembl
nucleoplasm Source: Ensembl
plasma membrane Source: Ensembl

Complete GO annotation...

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q3TKP4.

MaxQBⁱ

Q3TKP4.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000021456.
ExpressionAtlasⁱ	Q3TKP4. baseline and differential.

Interactionⁱ

GO - Molecular functionⁱ

identical protein binding Source: Ensembl

Complete GO annotation...

Structureⁱ

3D structure databases

SMRⁱ	Q3TKP4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	13 – 198	FBPaseInterPro annotationAdd BLAST		186

Sequence similaritiesⁱ

Belongs to the FBPase class 1 family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1458. Eukaryota. COG0158. LUCA.
HOVERGENⁱ	HBG005627.
KEGG Orthology (KO) More...KOⁱ	K03841.
OMAⁱ	MSDRSPF.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AZP.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00354. FBPase. 1 hit.
HAMAPⁱ	MF_01855. FBPase_class1. 1 hit.
InterProⁱ	View protein in InterPro IPR000146. FBPase_class-1. IPR033391. FBPase_N. IPR028343. FBPtase. IPR020548. Fructose_bisphosphatase_AS.
PANTHERⁱ	PTHR11556. PTHR11556. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00316. FBPase. 1 hit.
PIRSFⁱ	PIRSF500210. FBPtase. 1 hit. PIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSⁱ	PR00115. F16BPHPHTASE.
PROSITEⁱ	View protein in PROSITE PS00124. FBPASE. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q3TKP4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTDRSPFETD MLTLTRYVME KGRQAKGTGE LTQLLNSMLT AIKAISSAVR 
        60         70         80         90        100
KAGLANLYGI SGSVNVTGDE VKKLDVLSNS LVINMLQSSY STCVLVSEEN 
       110        120        130        140        150
KEAVITAQER RGKYVVCFDP LDGSSNIDCL ASIGTIFAIY RKTTEDEPSE 
       160        170        180        190        200
KDALQPGRNI VAAGYALYGS ATLVALSTGQ GVDLFMLDPA LGEFVLVEKD 
       210        220        230        240        250
VRIKKKGKIF SLNEGYAKYF DAATAEYVQK KKFPEDGSEP YGARYVGSMV 
       260        270        280        290        300
ADVHRTLVYG GIFMYPANQK SPNGKLRLLY ECNPVAYIIE QAGGMATTGT 
       310        320        330 
QPVLDVKPES IHQRVPLILG SPEDVQEYLS CVQRNQAGR

Length:339

Mass (Da):36,947

Last modified:October 11, 2005 - v1

Checksum:ⁱ442A3C5D09017415

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK146946 mRNA. Translation: BAE27555.1. AK166898 mRNA. Translation: BAE39101.1. AK166973 mRNA. Translation: BAE39156.1. CH466631 Genomic DNA. Translation: EDL16209.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_032020.2. NM_007994.3.
UniGeneⁱ	Mm.391871.

Genome annotation databases

GeneIDⁱ	14120.
KEGGⁱ	mmu:14120.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK146946 mRNA. Translation: BAE27555.1. AK166898 mRNA. Translation: BAE39101.1. AK166973 mRNA. Translation: BAE39156.1. CH466631 Genomic DNA. Translation: EDL16209.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_032020.2. NM_007994.3.
UniGeneⁱ	Mm.391871.

3D structure databases

SMRⁱ	Q3TKP4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q3TKP4.

MaxQBⁱ

Q3TKP4.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	14120.
KEGGⁱ	mmu:14120.

Organism-specific databases

CTDⁱ	8789.
MGIⁱ	MGI:95491. Fbp2.

Phylogenomic databases

eggNOGⁱ	KOG1458. Eukaryota. COG0158. LUCA.
HOVERGENⁱ	HBG005627.
KEGG Orthology (KO) More...KOⁱ	K03841.
OMAⁱ	MSDRSPF.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AZP.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000021456.
ExpressionAtlasⁱ	Q3TKP4. baseline and differential.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00354. FBPase. 1 hit.
HAMAPⁱ	MF_01855. FBPase_class1. 1 hit.
InterProⁱ	View protein in InterPro IPR000146. FBPase_class-1. IPR033391. FBPase_N. IPR028343. FBPtase. IPR020548. Fructose_bisphosphatase_AS.
PANTHERⁱ	PTHR11556. PTHR11556. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00316. FBPase. 1 hit.
PIRSFⁱ	PIRSF500210. FBPtase. 1 hit. PIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSⁱ	PR00115. F16BPHPHTASE.
PROSITEⁱ	View protein in PROSITE PS00124. FBPASE. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q3TKP4_MOUSE
Accessionⁱ	Q3TKP4Primary (citable) accession number: Q3TKP4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 11, 2005
	Last sequence update:	October 11, 2005
	Last modified:	July 5, 2017
	This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q3TKP4 (Q3TKP4_MOUSE)

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Fructose bisphosphatase 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ