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Protein
Submitted name:

ERBB receptor feedback inhibitor 1

Gene

Errfi1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
ERBB receptor feedback inhibitor 1Imported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Errfi1Imported
ORF Names:mCG_1312Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1921405. Errfi1.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000028967.
ExpressionAtlasiQ3TK48. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3TK48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 44GTPase_bindingInterPro annotationAdd BLAST41
Domaini314 – 368Inhibitor_Mig-6InterPro annotationAdd BLAST55

Phylogenomic databases

eggNOGiENOG410IEVS. Eukaryota.
ENOG4111HB5. LUCA.
HOVERGENiHBG031710.
OMAiNYAYFDA.
OrthoDBiEOG091G0BER.

Family and domain databases

Gene3Di4.10.680.10. 1 hit.
InterProiView protein in InterPro
IPR015116. Cdc42_binding_dom-like.
IPR021619. Mig-6.
PfamiView protein in Pfam
PF09027. GTPase_binding. 1 hit.
PF11555. Inhibitor_Mig-6. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TK48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTAGVAAQD IRVPLKTGFL HNGQALGNMK SCWGSHSEFE NNFLNIDPIT
60 70 80 90 100
MAYNLNSPAQ EHLTTVGCAA RSAPGSGHFF AECGPSPRSS LPPLVISPSE
110 120 130 140 150
SSGQREEDQV MCGFKKLSVN GVCTSTPPLT PIKSCPSPFP CAALCDRGSR
160 170 180 190 200
PLPPLPISED LCVDEADSEV ELLTTSSDTD LLLEDSAPSD FKYDAPGRRS
210 220 230 240 250
FRGCGQINYA YFDSPTVSVA DLSCASDQNR VVPDPNPPPP QSHRRLRRSH
260 270 280 290 300
SGPAGSFNKP AIRISSCTHR ASPSSDEDKP EVPPRVPIPP RPAKPDYRRW
310 320 330 340 350
SAEVTSNTYS DEDRPPKVPP REPLSRSNSR TPSPKSLPSY LNGVMPPTQS
360 370 380 390 400
FAPDPKYVSS KALQRQSSEG SANKVPCILP IIENGKKVSS THYYLLPERP
410 420 430 440 450
PYLDKYEKYF KEAEETNPST QIQPLPAACG MASATEKLAS RMKIDMGSHG
460
KRKHLSYVVS P
Length:461
Mass (Da):50,075
Last modified:October 11, 2005 - v1
Checksum:i0CA414516FAE27A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK166791 mRNA. Translation: BAE39021.1.
AK167156 mRNA. Translation: BAE39297.1.
CH466594 Genomic DNA. Translation: EDL14895.1.
RefSeqiNP_598514.1. NM_133753.1.
XP_006539273.1. XM_006539210.1.
UniGeneiMm.318841.

Genome annotation databases

GeneIDi74155.
KEGGimmu:74155.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ3TK48_MOUSE
AccessioniPrimary (citable) accession number: Q3TK48
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 5, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)