Q3TIV3 (Q3TIV3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAE39743.1

Gene names

Name:

Parp1 MGI 1340806

Organism

Mus musculus (Mouse) EMBL BAE39743.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1014 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PARP catalytic domain. SAAS SAAS012317

Ontologies

Gene Ontology (GO)
Biological_process	base-excision repair Inferred from mutant phenotype PubMed 11948190. Source: MGI protein ADP-ribosylation Inferred from electronic annotation. Source: InterPro regulation of growth rate Inferred from mutant phenotype PubMed 12707040. Source: MGI telomere maintenance Inferred from mutant phenotype PubMed 12707040. Source: MGI
Cellular_component	nucleolus Inferred from direct assay PubMed 15615785. Source: MGI nucleoplasm Inferred from direct assay PubMed 15615785. Source: MGI protein complex Inferred from direct assay PubMed 19796622. Source: MGI
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro NAD+ ADP-ribosyltransferase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3TIV3 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 4D2168E4CB3F4639	FASTA	1,014	112,711
	10 20 30 40 50 60 MAEASERLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV 70 80 90 100 110 120 GHSIRQPDVE VDGFSELRWD DQQKVKKTAE AGGVAGKGQD GSGGKAEKTL GDFLAEYAKS 130 140 150 160 170 180 NRSMCKGCLE KIEKGQMRLS KKMVDPEKPQ LGMIDRWYHP TCFVKKRDEL GFRPEYSASQ 190 200 210 220 230 240 LKGFSLLSAE DKEALKKQLP AIKNEGKRKG DEVDGTDEVA KKKSKKGKDK DSSKLEKALK 250 260 270 280 290 300 AQNELIWNIK DELKKACSTN DLKELLIFNQ QQVPSGESAI LDRVADGMAF GALLPCKECS 310 320 330 340 350 360 GQLVFKSDAY YCTGDVTAWT KCMVKTQNPS RKEWVTPKEF REISYLKKLK VKKQDRIFPP 370 380 390 400 410 420 ESSAPAPLAL PLSVTSAPTA VNSSAPADKP LSNMKILTLG KLSQNKDEAK AVIEKLGGKL 430 440 450 460 470 480 TGSANKASLC ISTKKEVEKM SKKMEEVKAA NVRVVCEDFL QDVSASTKSL QELLSAHSLS 490 500 510 520 530 540 SWGAEVKAEP GEVVASKGKS AAPSKKSKGA VKEEGVNKSE KRMKLTLKGG AAVDPDSGLE 550 560 570 580 590 600 HSAHVLEKGG KVFSATLGLV DIVKGTNSYY KLQLLEDDKE SRYWIFRSWG RVGTVIGSNK 610 620 630 640 650 660 LEQMPSKEDA VEHFMKLYEE KTGNAWHSKN FTKYPKKFYP LEIDYGQDEE AVKKLTVKPG 670 680 690 700 710 720 TKSKLPKPVQ ELVGMIFDVE SMKKALVEYE IDLQKMPLGK LSRRQIQAAY SILSEVQQAV 730 740 750 760 770 780 SQGSSESQIL DLSNRFYTLI PHDFGMKKPP LLNNADSVQA KVEMLDNLLD IEVAYSLLRG 790 800 810 820 830 840 GSDDSSKDPI DVNYEKLKTD IKVVDRDSEE AEVIRKYVKN THATTHNAYD LEVIDIFKIE 850 860 870 880 890 900 REGESQRYKP FRQLHNRRLL WHGSRTTNFA GILSQGLRIA PPEAPVTGYM FGKGIYFADM 910 920 930 940 950 960 VSKSANYCHT SQGDPIGLIL LGEVALGNMY ELKHASHISK LPKGKHSVKG LGKTTPDPSA 970 980 990 1000 1010 SITLEGVEVP LGTGIPSGVN DTCLLYNEYI VYDIAQVNLK YLLKLKFNFK TSLW

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE39743.1. Tissue: Amnion EMBL BAE39743.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE39743.1. Tissue: Amnion EMBL BAE39743.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE39743.1. Tissue: Amnion EMBL BAE39743.1.
[4]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE39743.1. Tissue: Amnion EMBL BAE39743.1.
[5]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE39743.1. Tissue: Amnion EMBL BAE39743.1.
[6]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE39743.1. Tissue: Amnion EMBL BAE39743.1.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE39743.1. Tissue: Amnion EMBL BAE39743.1.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE39743.1. Tissue: Amnion EMBL BAE39743.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK167699 mRNA. Translation: BAE39743.1.
IPI	IPI00139168.
UniGene	Mm.277779.
3D structure databases
ProteinModelPortal	Q3TIV3.
SMR	Q3TIV3. Positions 1-93, 105-360, 382-490, 520-643, 662-1011.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3TIV3.
Proteomic databases
PRIDE	Q3TIV3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:1340806. Parp1.
Phylogenomic databases
HOVERGEN	HBG053513.
InParanoid	Q3TIV3.
Gene expression databases
ArrayExpress	Q3TIV3.
Genevestigator	Q3TIV3.
Family and domain databases
Gene3D	1.20.142.10. 1 hit. 2.20.140.10. 1 hit. 3.30.1740.10. 2 hits.
InterPro	IPR001357. BRCT_dom. IPR008288. NAD_ADPRT. IPR012982. PADR1. IPR012317. Poly(ADP-ribose)pol_cat_dom. IPR004102. Poly(ADP-ribose)pol_reg_dom. IPR008893. WGR_domain. IPR001510. Znf_PARP. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF08063. PADR1. 1 hit. PF00644. PARP. 1 hit. PF02877. PARP_reg. 1 hit. PF05406. WGR. 1 hit. PF00645. zf-PARP. 2 hits. [Graphical view]
PIRSF	PIRSF000489. NAD_ADPRT. 1 hit.
SMART	SM00292. BRCT. 1 hit. SM00773. WGR. 1 hit. [Graphical view]
SUPFAM	SSF52113. BRCT. 1 hit. SSF47587. PARP_reg. 1 hit. SSF142921. SSF142921. 1 hit.
PROSITE	PS50172. BRCT. 1 hit. PS51060. PARP_ALPHA_HD. 1 hit. PS51059. PARP_CATALYTIC. 1 hit. PS00347. PARP_ZN_FINGER_1. 2 hits. PS50064. PARP_ZN_FINGER_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q3TIV3_MOUSE

Accession

Primary (citable) accession number: Q3TIV3

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	April 3, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)