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Protein

Proteasome endopeptidase complex

Gene

Psma7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Threonine proteasePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome endopeptidase complexPROSITE-ProRule annotation (EC:3.4.25.1PROSITE-ProRule annotation)
Gene namesi
Name:Psma7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1347070. Psma7.

Subcellular locationi

Keywords - Cellular componenti

CytoplasmPROSITE-ProRule annotation, ProteasomePROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ3THL2.
PeptideAtlasiQ3THL2.
PRIDEiQ3THL2.

Interactioni

Protein-protein interaction databases

IntActiQ3THL2. 1 interactor.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili155 – 178Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the peptidase T1A family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0183. Eukaryota.
ENOG410XP21. LUCA.
HOVERGENiHBG003005.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
InterProiView protein in InterPro
IPR029055. Ntn_hydrolases_N.
IPR023332. Proteasome_alpha-type.
IPR035190. Proteasome_alpha7.
IPR001353. Proteasome_sua/b.
PANTHERiPTHR11599:SF40. PTHR11599:SF40. 1 hit.
PfamiView protein in Pfam
PF00227. Proteasome. 1 hit.
SUPFAMiSSF56235. SSF56235. 1 hit.
PROSITEiView protein in PROSITE
PS51475. PROTEASOME_ALPHA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3THL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFAGLTADA RIVINRARVE CQSHRLTVED PVTVEYITRY IASLKQRYTQ
60 70 80 90 100
SNGRRPFGIS ALIVGFDFDG TPRLYQTDPS GTYHAWKANA IGRGAKSVRE
110 120 130 140 150
FLEKNYTDDA IETDDLTIKL VIKALLEVVQ SGGKNIELAV MRRDQPLKIL
160 170
NPEEIEKYVA EIEKEKEENE KKKQKKAS
Length:178
Mass (Da):20,189
Last modified:October 11, 2005 - v1
Checksum:iA71EB24246716920
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK168234 mRNA. Translation: BAE40184.1.
RefSeqiNP_001276405.1. NM_001289476.1.
UniGeneiMm.21728.

Genome annotation databases

GeneIDi26444.

Similar proteinsi

Entry informationi

Entry nameiQ3THL2_MOUSE
AccessioniPrimary (citable) accession number: Q3THL2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 25, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)