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Protein

Proteasome endopeptidase complex

Gene

Psma7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Threonine proteasePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome endopeptidase complexPROSITE-ProRule annotation (EC:3.4.25.1PROSITE-ProRule annotation)
Gene namesi
Name:Psma7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1347070. Psma7.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmPROSITE-ProRule annotation, ProteasomePROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ3THL2.
PeptideAtlasiQ3THL2.
PRIDEiQ3THL2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000027566.

Interactioni

Protein-protein interaction databases

IntActiQ3THL2. 1 interactor.
STRINGi10090.ENSMUSP00000029082.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili155 – 178Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the peptidase T1A family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0183. Eukaryota.
ENOG410XP21. LUCA.
HOVERGENiHBG003005.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
InterProiView protein in InterPro
IPR029055. Ntn_hydrolases_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
PfamiView protein in Pfam
PF00227. Proteasome. 1 hit.
SUPFAMiSSF56235. SSF56235. 1 hit.
PROSITEiView protein in PROSITE
PS51475. PROTEASOME_ALPHA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3THL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFAGLTADA RIVINRARVE CQSHRLTVED PVTVEYITRY IASLKQRYTQ
60 70 80 90 100
SNGRRPFGIS ALIVGFDFDG TPRLYQTDPS GTYHAWKANA IGRGAKSVRE
110 120 130 140 150
FLEKNYTDDA IETDDLTIKL VIKALLEVVQ SGGKNIELAV MRRDQPLKIL
160 170
NPEEIEKYVA EIEKEKEENE KKKQKKAS
Length:178
Mass (Da):20,189
Last modified:October 11, 2005 - v1
Checksum:iA71EB24246716920
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK168234 mRNA. Translation: BAE40184.1.
RefSeqiNP_001276405.1. NM_001289476.1.
UniGeneiMm.21728.

Genome annotation databases

GeneIDi26444.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK168234 mRNA. Translation: BAE40184.1.
RefSeqiNP_001276405.1. NM_001289476.1.
UniGeneiMm.21728.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ3THL2. 1 interactor.
STRINGi10090.ENSMUSP00000029082.

Proteomic databases

PaxDbiQ3THL2.
PeptideAtlasiQ3THL2.
PRIDEiQ3THL2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi26444.

Organism-specific databases

CTDi5688.
MGIiMGI:1347070. Psma7.

Phylogenomic databases

eggNOGiKOG0183. Eukaryota.
ENOG410XP21. LUCA.
HOVERGENiHBG003005.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000027566.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
InterProiView protein in InterPro
IPR029055. Ntn_hydrolases_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
PfamiView protein in Pfam
PF00227. Proteasome. 1 hit.
SUPFAMiSSF56235. SSF56235. 1 hit.
PROSITEiView protein in PROSITE
PS51475. PROTEASOME_ALPHA_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3THL2_MOUSE
AccessioniPrimary (citable) accession number: Q3THL2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: February 15, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.