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Protein
Submitted name:

Uncharacterized protein

Gene

Afp

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:AfpImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:87951. Afp.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedPROSITE-ProRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi68 ↔ 83UniRule annotation
Disulfide bondi82 ↔ 93UniRule annotation
Disulfide bondi117 ↔ 162UniRule annotation
Disulfide bondi161 ↔ 170UniRule annotation
Disulfide bondi193 ↔ 239UniRule annotation
Disulfide bondi238 ↔ 246UniRule annotation
Disulfide bondi258 ↔ 272UniRule annotation
Disulfide bondi271 ↔ 282UniRule annotation
Disulfide bondi353 ↔ 362UniRule annotation
Disulfide bondi385 ↔ 431UniRule annotation
Disulfide bondi430 ↔ 441UniRule annotation
Disulfide bondi454 ↔ 470UniRule annotation
Disulfide bondi469 ↔ 480UniRule annotation
Disulfide bondi507 ↔ 552UniRule annotation
Disulfide bondi551 ↔ 560UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Proteomic databases

PaxDbiQ3TGA3.
PeptideAtlasiQ3TGA3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 180AlbuminInterPro annotationAdd BLAST180
Domaini181 – 371AlbuminInterPro annotationAdd BLAST191
Domaini372 – 570AlbuminInterPro annotationAdd BLAST199

Sequence similaritiesi

Belongs to the ALB/AFP/VDB family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IIRZ. Eukaryota.
ENOG410Z40H. LUCA.
HOVERGENiHBG004207.

Family and domain databases

CDDicd00015. ALBUMIN. 3 hits.
InterProiView protein in InterPro
IPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP/Afamin.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
PANTHERiPTHR11385. PTHR11385. 1 hit.
PfamiView protein in Pfam
PF00273. Serum_albumin. 3 hits.
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00803. AFETOPROTEIN.
PR00802. SERUMALBUMIN.
SMARTiView protein in SMART
SM00103. ALBUMIN. 3 hits.
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiView protein in PROSITE
PS00212. ALBUMIN_1. 2 hits.
PS51438. ALBUMIN_2. 3 hits.

Sequencei

Sequence statusi: Fragment.

Q3TGA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IASTLDSSQC VTEKNVLSIA TITFTQFVPE ATEEEVNKMT SDVLAAMKKN
60 70 80 90 100
SGDGCLESQL SVFLDEICHE TELSNKYGLS GCCSQSGVER HQCLLARKKT
110 120 130 140 150
APASVPPFQF PEPAESCKAH EENRAVFMNR FIYEVSRRNP FMYAPAILSL
160 170 180 190 200
AAQYDKVVLA CCKADNKEEC FQTKRASIAK ELREGSMLNE HVCSVIRKFG
210 220 230 240 250
SRNLQATTII KLSQKLTEAN FTEIQKLALD VAHIHEECCQ GNSLECLQDG
260 270 280 290 300
EKVMTYICSQ QNILSSKIAE CCKLPMIQLG FCIIHAENGV KPEGLSLNPS
310 320 330 340 350
QFLGDRNFAQ FSSEEKIMFM ASFLHEYSRT HPNLPVSVIL RIAKTYQEIL
360 370 380 390 400
EKCSQSGNLP GCQDNLEEEL QKHIEESQAL SKQSCALYQT LGDYKLQNLF
410 420 430 440 450
LIGYTRKAPQ LTSAELIDLT GKMVSIASTC CQLSEEKWSG CGEGMADIFI
460 470 480 490 500
GHLCIRNEAS PVNSGISHCC NSSYSNRRLC ITSFLRDETY APPPFSEDKF
510 520 530 540 550
IFHKDLCQAQ GKALQTMKQE LLINLVKQKP ELTEEQLAAV TADFSGLLEK
560 570
CCKAQDQEVC FTEEGPKLIS KTRDALGV
Length:578
Mass (Da):64,317
Last modified:October 11, 2005 - v1
Checksum:iC678EF5D63024C50
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK168818 mRNA. Translation: BAE40645.1.
UniGeneiMm.358570.

Similar proteinsi

Entry informationi

Entry nameiQ3TGA3_MOUSE
AccessioniPrimary (citable) accession number: Q3TGA3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 27, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation