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Protein
Submitted name:

Putative uncharacterized protein

Gene

Afp

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:AfpImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:87951. Afp.

Subcellular locationi

  • Secreted PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedPROSITE-ProRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi82 ↔ 93PROSITE-ProRule annotation
Disulfide bondi117 ↔ 162PROSITE-ProRule annotation
Disulfide bondi161 ↔ 170PROSITE-ProRule annotation
Disulfide bondi193 ↔ 239PROSITE-ProRule annotation
Disulfide bondi238 ↔ 246PROSITE-ProRule annotation
Disulfide bondi271 ↔ 282PROSITE-ProRule annotation
Disulfide bondi353 ↔ 362PROSITE-ProRule annotation
Disulfide bondi385 ↔ 431PROSITE-ProRule annotation
Disulfide bondi469 ↔ 480PROSITE-ProRule annotation
Disulfide bondi507 ↔ 552PROSITE-ProRule annotation
Disulfide bondi551 ↔ 560PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PaxDbiQ3TGA3.
PeptideAtlasiQ3TGA3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000054932.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041006.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 180AlbuminInterPro annotationAdd BLAST180
Domaini181 – 371AlbuminInterPro annotationAdd BLAST191
Domaini372 – 570AlbuminInterPro annotationAdd BLAST199

Sequence similaritiesi

Belongs to the ALB/AFP/VDB family.PROSITE-ProRule annotation
Contains 3 albumin domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IIRZ. Eukaryota.
ENOG410Z40H. LUCA.
HOVERGENiHBG004207.

Family and domain databases

CDDicd00015. ALBUMIN. 3 hits.
InterProiIPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP/Afamin.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
[Graphical view]
PfamiPF00273. Serum_albumin. 3 hits.
[Graphical view]
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00803. AFETOPROTEIN.
PR00802. SERUMALBUMIN.
SMARTiSM00103. ALBUMIN. 3 hits.
[Graphical view]
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiPS00212. ALBUMIN_1. 2 hits.
PS51438. ALBUMIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3TGA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IASTLDSSQC VTEKNVLSIA TITFTQFVPE ATEEEVNKMT SDVLAAMKKN
60 70 80 90 100
SGDGCLESQL SVFLDEICHE TELSNKYGLS GCCSQSGVER HQCLLARKKT
110 120 130 140 150
APASVPPFQF PEPAESCKAH EENRAVFMNR FIYEVSRRNP FMYAPAILSL
160 170 180 190 200
AAQYDKVVLA CCKADNKEEC FQTKRASIAK ELREGSMLNE HVCSVIRKFG
210 220 230 240 250
SRNLQATTII KLSQKLTEAN FTEIQKLALD VAHIHEECCQ GNSLECLQDG
260 270 280 290 300
EKVMTYICSQ QNILSSKIAE CCKLPMIQLG FCIIHAENGV KPEGLSLNPS
310 320 330 340 350
QFLGDRNFAQ FSSEEKIMFM ASFLHEYSRT HPNLPVSVIL RIAKTYQEIL
360 370 380 390 400
EKCSQSGNLP GCQDNLEEEL QKHIEESQAL SKQSCALYQT LGDYKLQNLF
410 420 430 440 450
LIGYTRKAPQ LTSAELIDLT GKMVSIASTC CQLSEEKWSG CGEGMADIFI
460 470 480 490 500
GHLCIRNEAS PVNSGISHCC NSSYSNRRLC ITSFLRDETY APPPFSEDKF
510 520 530 540 550
IFHKDLCQAQ GKALQTMKQE LLINLVKQKP ELTEEQLAAV TADFSGLLEK
560 570
CCKAQDQEVC FTEEGPKLIS KTRDALGV
Length:578
Mass (Da):64,317
Last modified:October 11, 2005 - v1
Checksum:iC678EF5D63024C50
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK168818 mRNA. Translation: BAE40645.1.
UniGeneiMm.358570.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK168818 mRNA. Translation: BAE40645.1.
UniGeneiMm.358570.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041006.

Proteomic databases

PaxDbiQ3TGA3.
PeptideAtlasiQ3TGA3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:87951. Afp.

Phylogenomic databases

eggNOGiENOG410IIRZ. Eukaryota.
ENOG410Z40H. LUCA.
HOVERGENiHBG004207.

Miscellaneous databases

ChiTaRSiAfp. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000054932.

Family and domain databases

CDDicd00015. ALBUMIN. 3 hits.
InterProiIPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR021177. Serum_albumin/AFP/Afamin.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
[Graphical view]
PfamiPF00273. Serum_albumin. 3 hits.
[Graphical view]
PIRSFiPIRSF002520. Serum_albumin_subgroup. 1 hit.
PRINTSiPR00803. AFETOPROTEIN.
PR00802. SERUMALBUMIN.
SMARTiSM00103. ALBUMIN. 3 hits.
[Graphical view]
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiPS00212. ALBUMIN_1. 2 hits.
PS51438. ALBUMIN_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3TGA3_MOUSE
AccessioniPrimary (citable) accession number: Q3TGA3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: January 18, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.