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Protein

SPRY domain-containing protein 7

Gene

Spryd7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
SPRY domain-containing protein 7
Alternative name(s):
Chronic lymphocytic leukemia deletion region gene 6 protein homolog
Short name:
CLL deletion region gene 6 protein homolog
Gene namesi
Name:Spryd7
Synonyms:Clld6
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1913924. Spryd7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002439262 – 196SPRY domain-containing protein 7Add BLAST195

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ3TFQ1.
MaxQBiQ3TFQ1.
PaxDbiQ3TFQ1.
PeptideAtlasiQ3TFQ1.
PRIDEiQ3TFQ1.

PTM databases

PhosphoSitePlusiQ3TFQ1.
SwissPalmiQ3TFQ1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000021930.
CleanExiMM_6330409N04RIK.
ExpressionAtlasiQ3TFQ1. baseline and differential.
GenevisibleiQ3TFQ1. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022497.

Structurei

3D structure databases

ProteinModelPortaliQ3TFQ1.
SMRiQ3TFQ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 184B30.2/SPRYPROSITE-ProRule annotationAdd BLAST183

Sequence similaritiesi

Contains 1 B30.2/SPRY domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4030. Eukaryota.
ENOG410XNNE. LUCA.
GeneTreeiENSGT00390000011048.
HOVERGENiHBG056533.
InParanoidiQ3TFQ1.
OMAiYDHVEMN.
OrthoDBiEOG091G0KM6.
PhylomeDBiQ3TFQ1.
TreeFamiTF314996.

Family and domain databases

InterProiIPR001870. B30.2/SPRY.
IPR013320. ConA-like_dom.
IPR003877. SPRY_dom.
[Graphical view]
PfamiPF00622. SPRY. 1 hit.
[Graphical view]
SMARTiSM00449. SPRY. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS50188. B302_SPRY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3TFQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASAWCCLR CCRDGGTGHI PLKEMPAVQL DTQHMGTDVV IVKNGRRICG
60 70 80 90 100
TGGCLASAPL HQNKSYFEFK IQSTGIWGIG VATQKVNLNQ IPLGRDMHSL
110 120 130 140 150
VMRNDGALYH NNEEKNRLPA NSLPQEGDVV GITYDHVELN VYLNGKNMHC
160 170 180 190
PASGIRGTVY PVVYVDDSAI LDCQFSEFYH TPPPGFEKIL FEQQIF
Length:196
Mass (Da):21,681
Last modified:June 27, 2006 - v2
Checksum:i238C69FC296A4C57
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti7C → S in BAB31148 (PubMed:16141072).Curated1
Sequence conflicti174Q → E in BAB31049 (PubMed:16141072).Curated1
Sequence conflicti179Y → H in BAB31148 (PubMed:16141072).Curated1
Sequence conflicti186F → V in BAB31049 (PubMed:16141072).Curated1
Sequence conflicti194Q → R in BAE40847 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018044 mRNA. Translation: BAB31049.1.
AK018153 mRNA. Translation: BAB31097.2.
AK018290 mRNA. Translation: BAB31148.1.
AK137685 mRNA. Translation: BAE23460.1.
AK167306 mRNA. Translation: BAE39410.1.
AK169059 mRNA. Translation: BAE40847.1.
BC037015 mRNA. Translation: AAH37015.1.
CCDSiCCDS27185.1.
RefSeqiNP_001297532.1. NM_001310603.1.
NP_079973.1. NM_025697.4.
UniGeneiMm.282706.

Genome annotation databases

EnsembliENSMUST00000022497; ENSMUSP00000022497; ENSMUSG00000021930.
GeneIDi66674.
KEGGimmu:66674.
UCSCiuc007ufx.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018044 mRNA. Translation: BAB31049.1.
AK018153 mRNA. Translation: BAB31097.2.
AK018290 mRNA. Translation: BAB31148.1.
AK137685 mRNA. Translation: BAE23460.1.
AK167306 mRNA. Translation: BAE39410.1.
AK169059 mRNA. Translation: BAE40847.1.
BC037015 mRNA. Translation: AAH37015.1.
CCDSiCCDS27185.1.
RefSeqiNP_001297532.1. NM_001310603.1.
NP_079973.1. NM_025697.4.
UniGeneiMm.282706.

3D structure databases

ProteinModelPortaliQ3TFQ1.
SMRiQ3TFQ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022497.

PTM databases

PhosphoSitePlusiQ3TFQ1.
SwissPalmiQ3TFQ1.

Proteomic databases

EPDiQ3TFQ1.
MaxQBiQ3TFQ1.
PaxDbiQ3TFQ1.
PeptideAtlasiQ3TFQ1.
PRIDEiQ3TFQ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022497; ENSMUSP00000022497; ENSMUSG00000021930.
GeneIDi66674.
KEGGimmu:66674.
UCSCiuc007ufx.1. mouse.

Organism-specific databases

CTDi57213.
MGIiMGI:1913924. Spryd7.

Phylogenomic databases

eggNOGiKOG4030. Eukaryota.
ENOG410XNNE. LUCA.
GeneTreeiENSGT00390000011048.
HOVERGENiHBG056533.
InParanoidiQ3TFQ1.
OMAiYDHVEMN.
OrthoDBiEOG091G0KM6.
PhylomeDBiQ3TFQ1.
TreeFamiTF314996.

Miscellaneous databases

PROiQ3TFQ1.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021930.
CleanExiMM_6330409N04RIK.
ExpressionAtlasiQ3TFQ1. baseline and differential.
GenevisibleiQ3TFQ1. MM.

Family and domain databases

InterProiIPR001870. B30.2/SPRY.
IPR013320. ConA-like_dom.
IPR003877. SPRY_dom.
[Graphical view]
PfamiPF00622. SPRY. 1 hit.
[Graphical view]
SMARTiSM00449. SPRY. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS50188. B302_SPRY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPRY7_MOUSE
AccessioniPrimary (citable) accession number: Q3TFQ1
Secondary accession number(s): Q8K1Y1
, Q9CU44, Q9D368, Q9D3D1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 27, 2006
Last modified: November 2, 2016
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.