Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q3TFQ1

- SPRY7_MOUSE

UniProt

Q3TFQ1 - SPRY7_MOUSE

Protein

SPRY domain-containing protein 7

Gene

Spryd7

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 2 (27 Jun 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SPRY domain-containing protein 7
    Alternative name(s):
    Chronic lymphocytic leukemia deletion region gene 6 protein homolog
    Short name:
    CLL deletion region gene 6 protein homolog
    Gene namesi
    Name:Spryd7
    Synonyms:Clld6
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:1913924. Spryd7.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 196195SPRY domain-containing protein 7PRO_0000243926Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanineBy similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiQ3TFQ1.
    PaxDbiQ3TFQ1.
    PRIDEiQ3TFQ1.

    PTM databases

    PhosphoSiteiQ3TFQ1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ3TFQ1.
    BgeeiQ3TFQ1.
    CleanExiMM_6330409N04RIK.
    GenevestigatoriQ3TFQ1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3TFQ1.
    SMRiQ3TFQ1. Positions 25-189.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 184183B30.2/SPRYPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 B30.2/SPRY domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG291635.
    GeneTreeiENSGT00390000011048.
    HOVERGENiHBG056533.
    InParanoidiQ3TFQ1.
    OMAiGGSGHIP.
    OrthoDBiEOG7J447S.
    PhylomeDBiQ3TFQ1.
    TreeFamiTF314996.

    Family and domain databases

    InterProiIPR001870. B30.2/SPRY.
    IPR008985. ConA-like_lec_gl_sf.
    IPR018355. SPla/RYanodine_receptor_subgr.
    IPR003877. SPRY_rcpt.
    [Graphical view]
    PfamiPF00622. SPRY. 1 hit.
    [Graphical view]
    SMARTiSM00449. SPRY. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    PROSITEiPS50188. B302_SPRY. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q3TFQ1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAASAWCCLR CCRDGGTGHI PLKEMPAVQL DTQHMGTDVV IVKNGRRICG    50
    TGGCLASAPL HQNKSYFEFK IQSTGIWGIG VATQKVNLNQ IPLGRDMHSL 100
    VMRNDGALYH NNEEKNRLPA NSLPQEGDVV GITYDHVELN VYLNGKNMHC 150
    PASGIRGTVY PVVYVDDSAI LDCQFSEFYH TPPPGFEKIL FEQQIF 196
    Length:196
    Mass (Da):21,681
    Last modified:June 27, 2006 - v2
    Checksum:i238C69FC296A4C57
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti7 – 71C → S in BAB31148. (PubMed:16141072)Curated
    Sequence conflicti174 – 1741Q → E in BAB31049. (PubMed:16141072)Curated
    Sequence conflicti179 – 1791Y → H in BAB31148. (PubMed:16141072)Curated
    Sequence conflicti186 – 1861F → V in BAB31049. (PubMed:16141072)Curated
    Sequence conflicti194 – 1941Q → R in BAE40847. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK018044 mRNA. Translation: BAB31049.1.
    AK018153 mRNA. Translation: BAB31097.2.
    AK018290 mRNA. Translation: BAB31148.1.
    AK137685 mRNA. Translation: BAE23460.1.
    AK167306 mRNA. Translation: BAE39410.1.
    AK169059 mRNA. Translation: BAE40847.1.
    BC037015 mRNA. Translation: AAH37015.1.
    CCDSiCCDS27185.1.
    RefSeqiNP_079973.1. NM_025697.3.
    UniGeneiMm.282706.

    Genome annotation databases

    EnsembliENSMUST00000022497; ENSMUSP00000022497; ENSMUSG00000021930.
    GeneIDi66674.
    KEGGimmu:66674.
    UCSCiuc007ufx.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK018044 mRNA. Translation: BAB31049.1 .
    AK018153 mRNA. Translation: BAB31097.2 .
    AK018290 mRNA. Translation: BAB31148.1 .
    AK137685 mRNA. Translation: BAE23460.1 .
    AK167306 mRNA. Translation: BAE39410.1 .
    AK169059 mRNA. Translation: BAE40847.1 .
    BC037015 mRNA. Translation: AAH37015.1 .
    CCDSi CCDS27185.1.
    RefSeqi NP_079973.1. NM_025697.3.
    UniGenei Mm.282706.

    3D structure databases

    ProteinModelPortali Q3TFQ1.
    SMRi Q3TFQ1. Positions 25-189.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q3TFQ1.

    Proteomic databases

    MaxQBi Q3TFQ1.
    PaxDbi Q3TFQ1.
    PRIDEi Q3TFQ1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000022497 ; ENSMUSP00000022497 ; ENSMUSG00000021930 .
    GeneIDi 66674.
    KEGGi mmu:66674.
    UCSCi uc007ufx.1. mouse.

    Organism-specific databases

    CTDi 57213.
    MGIi MGI:1913924. Spryd7.

    Phylogenomic databases

    eggNOGi NOG291635.
    GeneTreei ENSGT00390000011048.
    HOVERGENi HBG056533.
    InParanoidi Q3TFQ1.
    OMAi GGSGHIP.
    OrthoDBi EOG7J447S.
    PhylomeDBi Q3TFQ1.
    TreeFami TF314996.

    Miscellaneous databases

    NextBioi 322341.
    PROi Q3TFQ1.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3TFQ1.
    Bgeei Q3TFQ1.
    CleanExi MM_6330409N04RIK.
    Genevestigatori Q3TFQ1.

    Family and domain databases

    InterProi IPR001870. B30.2/SPRY.
    IPR008985. ConA-like_lec_gl_sf.
    IPR018355. SPla/RYanodine_receptor_subgr.
    IPR003877. SPRY_rcpt.
    [Graphical view ]
    Pfami PF00622. SPRY. 1 hit.
    [Graphical view ]
    SMARTi SM00449. SPRY. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    PROSITEi PS50188. B302_SPRY. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Kidney, Medulla oblongata, Olfactory bulb, Placenta, Thymus and Vagina.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Mammary tumor.

    Entry informationi

    Entry nameiSPRY7_MOUSE
    AccessioniPrimary (citable) accession number: Q3TFQ1
    Secondary accession number(s): Q8K1Y1
    , Q9CU44, Q9D368, Q9D3D1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: June 27, 2006
    Last modified: October 1, 2014
    This is version 64 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3