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Q3TDT5 (Q3TDT5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:Il6st MGI 96560
OrganismMus musculus (Mouse) EMBL BAE41514.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length164 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processglycogen metabolic process

Inferred from mutant phenotype PubMed 10205167. Source: MGI

interleukin-11-mediated signaling pathway

Inferred from direct assay PubMed 7957045. Source: GOC

interleukin-27-mediated signaling pathway

Inferred from electronic annotation. Source: Compara

negative regulation of interleukin-6-mediated signaling pathway

Inferred from electronic annotation. Source: Compara

positive regulation of T cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of astrocyte differentiation

Inferred from mutant phenotype PubMed 10486560. Source: MGI

positive regulation of cell proliferation

Inferred from genetic interaction PubMed 15051883. Source: MGI

positive regulation of osteoblast differentiation

Inferred from electronic annotation. Source: Compara

positive regulation of tyrosine phosphorylation of Stat1 protein

Inferred from electronic annotation. Source: Compara

positive regulation of tyrosine phosphorylation of Stat3 protein

Inferred from electronic annotation. Source: Compara

regulation of Notch signaling pathway

Inferred from direct assay PubMed 12629177. Source: MGI

   Cellular_componentciliary neurotrophic factor receptor complex

Inferred from electronic annotation. Source: Compara

dendrite

Inferred from direct assay PubMed 10989258. Source: MGI

external side of plasma membrane

Inferred from direct assay PubMed 11275690. Source: MGI

extracellular space

Inferred from electronic annotation. Source: Compara

interleukin-6 receptor complex

Inferred from electronic annotation. Source: Compara

neuronal cell body

Inferred from direct assay PubMed 10989258. Source: MGI

oncostatin-M receptor complex

Inferred from electronic annotation. Source: Compara

   Molecular_functioninterleukin-6 receptor activity

Inferred from electronic annotation. Source: Compara

leukemia inhibitory factor receptor activity

Inferred from electronic annotation. Source: Compara

oncostatin-M receptor activity

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q3TDT5 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: CD2D736EB32CC0AA

FASTA16418,538
        10         20         30         40         50         60 
MSAPRIWLAQ ALLFFLTTES IGQLLEPCGY IYPEFPVVQR GSNFTAICVL KEACLQHYYV 

        70         80         90        100        110        120 
NASYIVWKTN HAAVPREQVT VINRTTSSVT FTDVVLPSVQ LTCNILSFGQ IEQNVYGVTM 

       130        140        150        160 
LSGFPPDKPT NLTCIVNEGK NMLCQWDPGR ETYLETNYTL KSEW 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE41514.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE41514.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE41514.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE41514.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE41514.1.
[6]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE41514.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE41514.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NOD EMBL BAE41514.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK170020 mRNA. Translation: BAE41514.1.
IPIIPI00120155.
UniGeneMm.4364.

3D structure databases

ProteinModelPortalQ3TDT5.
SMRQ3TDT5. Positions 24-164.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc007rwf.2. mouse.

Organism-specific databases

MGIMGI:96560. Il6st.

Phylogenomic databases

InParanoidQ3TDT5.

Gene expression databases

ArrayExpressQ3TDT5.
BgeeQ3TDT5.
GenevestigatorQ3TDT5.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
InterProIPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR010457. IgC2-like_lig-bd.
IPR015321. IL6_recept-bd.
[Graphical view]
PfamPF09240. IL6Ra-bind. 1 hit.
PF06328. Lep_receptor_Ig. 1 hit.
[Graphical view]
SUPFAMSSF49265. FN_III-like. 2 hits.
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ3TDT5_MOUSE
AccessionPrimary (citable) accession number: Q3TDT5
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 29, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)