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Q3TDT5

- Q3TDT5_MOUSE

UniProt

Q3TDT5 - Q3TDT5_MOUSE

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Protein
Submitted name:

Interleukin-6 receptor subunit beta

Gene
Il6st
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. interleukin-6 receptor activity Source: Ensembl
  2. leukemia inhibitory factor receptor activity Source: Ensembl
  3. oncostatin-M receptor activity Source: Ensembl
  4. protein binding Source: MGI

GO - Biological processi

  1. cytokine-mediated signaling pathway Source: MGI
  2. glycogen metabolic process Source: MGI
  3. interleukin-11-mediated signaling pathway Source: GOC
  4. interleukin-27-mediated signaling pathway Source: Ensembl
  5. negative regulation of interleukin-6-mediated signaling pathway Source: Ensembl
  6. positive regulation of astrocyte differentiation Source: MGI
  7. positive regulation of cell proliferation Source: MGI
  8. positive regulation of osteoblast differentiation Source: Ensembl
  9. positive regulation of T cell proliferation Source: Ensembl
  10. positive regulation of tyrosine phosphorylation of Stat1 protein Source: Ensembl
  11. positive regulation of tyrosine phosphorylation of Stat3 protein Source: Ensembl
  12. regulation of Notch signaling pathway Source: MGI
  13. signal transduction Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-6 receptor subunit betaImported
Gene namesi
Name:Il6stImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:96560. Il6st.

Subcellular locationi

GO - Cellular componenti

  1. cell body Source: MGI
  2. ciliary neurotrophic factor receptor complex Source: Ensembl
  3. dendrite Source: MGI
  4. external side of plasma membrane Source: MGI
  5. extracellular space Source: Ensembl
  6. interleukin-6 receptor complex Source: Ensembl
  7. neuronal cell body Source: MGI
  8. oncostatin-M receptor complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ3TDT5.
GenevestigatoriQ3TDT5.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074436.
InParanoidiQ3TDT5.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR010457. IgC2-like_lig-bd.
IPR015321. IL-6_rcpt_alpha-bd.
[Graphical view]
PfamiPF09240. IL6Ra-bind. 1 hit.
PF06328. Lep_receptor_Ig. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.

Sequencei

Sequence statusi: Complete.

Q3TDT5-1 [UniParc]FASTAAdd to Basket

« Hide

MSAPRIWLAQ ALLFFLTTES IGQLLEPCGY IYPEFPVVQR GSNFTAICVL    50
KEACLQHYYV NASYIVWKTN HAAVPREQVT VINRTTSSVT FTDVVLPSVQ 100
LTCNILSFGQ IEQNVYGVTM LSGFPPDKPT NLTCIVNEGK NMLCQWDPGR 150
ETYLETNYTL KSEW 164
Length:164
Mass (Da):18,538
Last modified:October 11, 2005 - v1
Checksum:iCD2D736EB32CC0AA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC159196 Genomic DNA. No translation available.
AK170020 mRNA. Translation: BAE41514.1.
UniGeneiMm.4364.

Genome annotation databases

EnsembliENSMUST00000183886; ENSMUSP00000138820; ENSMUSG00000021756.
UCSCiuc007rwf.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC159196 Genomic DNA. No translation available.
AK170020 mRNA. Translation: BAE41514.1 .
UniGenei Mm.4364.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000183886 ; ENSMUSP00000138820 ; ENSMUSG00000021756 .
UCSCi uc007rwf.2. mouse.

Organism-specific databases

MGIi MGI:96560. Il6st.

Phylogenomic databases

GeneTreei ENSGT00550000074436.
InParanoidi Q3TDT5.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q3TDT5.
Genevestigatori Q3TDT5.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
InterProi IPR003961. Fibronectin_type3.
IPR013783. Ig-like_fold.
IPR010457. IgC2-like_lig-bd.
IPR015321. IL-6_rcpt_alpha-bd.
[Graphical view ]
Pfami PF09240. IL6Ra-bind. 1 hit.
PF06328. Lep_receptor_Ig. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (DEC-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3TDT5_MOUSE
AccessioniPrimary (citable) accession number: Q3TDT5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 11, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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