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Protein
Submitted name:

Tapasin

Gene

Tapbp

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1236974. ER-Phagosome pathway.
R-MMU-983170. Antigen Presentation: Folding, assembly and peptide loading of class I MHC.

Names & Taxonomyi

Protein namesi
Submitted name:
TapasinImported
Gene namesi
Name:TapbpImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1201689. Tapbp.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei417 – 441HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501084325924 – 466Sequence analysisAdd BLAST443

Expressioni

Gene expression databases

BgeeiENSMUSG00000024308.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini295 – 402Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST108

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410II43. Eukaryota.
ENOG4111QPK. LUCA.
GeneTreeiENSGT00530000063758.
HOGENOMiHOG000231214.
HOVERGENiHBG005156.
OMAiHGARYAC.
OrthoDBiEOG091G0ATU.
TreeFamiTF334274.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR008056. Tapasin.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PRINTSiPR01669. TAPASIN.
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3TCU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPLLLLVAV ALGLATVVSV VSAGPEAIEC WFVEDAGGGG LSKKPATLLL
60 70 80 90 100
RHGPRGPPPR PDLDPKLYFK VDDPAGMLLA AFRRYPAGAS APHCEMSRFI
110 120 130 140 150
PFPASAKWAR SLSPEQNCPR ALDGDWLLVS VSSTLFSLSS LLRPQPEPLR
160 170 180 190 200
EPVVITMATV VLTVLTHNPA PRVQLGKDAV LDLRFAYAPS ALEGSPSLDA
210 220 230 240 250
GPPPFGLEWR RQHRGKGHLL LAATPGLAGR MPPAQEKATA FAAWDDDEPW
260 270 280 290 300
GPWTGNGTFW LPAVKPSQEG VYLATVHLPY LQGQVSLELT VHKAPRVSLT
310 320 330 340 350
PAPVVWAAPG EAPPELLCLA SHFFPAEGLE VKWELRGGPG GSSRKVEGKT
360 370 380 390 400
WLSTIRHHSD GSVSQSGHLQ LPPVTAKQHG VHYVCRVYHS SLPASGRSAD
410 420 430 440 450
VTLEVAGFSG PSIEDGIGLF LSAFLLLGLL KVLGWLVAAY WTIPEVSKEK
460
ATAASLTIPR NSKKSQ
Length:466
Mass (Da):49,836
Last modified:October 11, 2005 - v1
Checksum:i0184756D434DB3CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974462 Genomic DNA. No translation available.
AK151807 mRNA. Translation: BAE30706.1.
AK170528 mRNA. Translation: BAE41860.1.
RefSeqiNP_001020484.1. NM_001025313.1.
UniGeneiMm.154457.

Genome annotation databases

EnsembliENSMUST00000025161; ENSMUSP00000025161; ENSMUSG00000024308.
GeneIDi21356.
UCSCiuc008caf.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ3TCU5_MOUSE
AccessioniPrimary (citable) accession number: Q3TCU5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: August 30, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported