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Protein
Submitted name:

Putative uncharacterized protein

Gene

Vapb

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. beta-tubulin binding Source: MGI
  2. enzyme binding Source: MGI
  3. FFAT motif binding Source: MGI
  4. microtubule binding Source: MGI
  5. protein heterodimerization activity Source: MGI
  6. protein homodimerization activity Source: MGI

GO - Biological processi

  1. activation of signaling protein activity involved in unfolded protein response Source: MGI
  2. cellular calcium ion homeostasis Source: MGI
  3. COPII-coated vesicle budding Source: MGI
  4. endoplasmic reticulum organization Source: MGI
  5. endoplasmic reticulum unfolded protein response Source: MGI
  6. ER to Golgi vesicle-mediated transport Source: MGI
  7. modulation by virus of host morphology or physiology Source: MGI
  8. negative regulation by host of viral genome replication Source: MGI
  9. negative regulation by host of viral release from host cell Source: MGI
  10. negative regulation by virus of viral protein levels in host cell Source: MGI
  11. positive regulation by host of viral genome replication Source: MGI
  12. positive regulation by host of viral release from host cell Source: MGI
  13. positive regulation of viral genome replication Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_335233. Sphingolipid de novo biosynthesis.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:VapbImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1928744. Vapb.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: MGI
  2. endoplasmic reticulum membrane Source: MGI
  3. Golgi apparatus Source: MGI
  4. Golgi membrane Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ3TA54.

Expressioni

Gene expression databases

BgeeiQ3TA54.
ExpressionAtlasiQ3TA54. baseline and differential.
GenevestigatoriQ3TA54.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG028551.

Family and domain databases

Gene3Di2.60.40.360. 1 hit.
InterProiIPR000535. MSP_dom.
IPR008962. PapD-like.
IPR016763. VAP.
IPR030226. VapB.
[Graphical view]
PANTHERiPTHR10809. PTHR10809. 1 hit.
PTHR10809:SF12. PTHR10809:SF12. 1 hit.
PfamiPF00635. Motile_Sperm. 1 hit.
[Graphical view]
SUPFAMiSSF49354. SSF49354. 1 hit.
PROSITEiPS50202. MSP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3TA54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QHELKFRGPF TDVVTTNLKL GNPTDRNVCF KVKTTAPRRY CVRPNSGVID
60 70 80 90 100
AGASLNVSVM LQPFDYDPNE KSKHKFMVQS MFAPPDTSDM EAVWKEAKPE
110 120 130 140 150
DLMDSKLRCV FELPAENAKP HDVEINKIIP TSASKTEAPA AAKSLTSPLD
160 170 180 190 200
DTEVKKEEDG LRVRKAMPSN SPVAALAATG KEEGLSARLL ALVVLFFIVG

VIIGKIAL
Length:208
Mass (Da):22,737
Last modified:October 11, 2005 - v1
Checksum:iD14686AC7BCBDB05
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK172080 mRNA. Translation: BAE42816.1.
UniGeneiMm.260456.

Genome annotation databases

UCSCiuc012ckt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK172080 mRNA. Translation: BAE42816.1.
UniGeneiMm.260456.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ3TA54.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc012ckt.1. mouse.

Organism-specific databases

MGIiMGI:1928744. Vapb.

Phylogenomic databases

HOVERGENiHBG028551.

Enzyme and pathway databases

ReactomeiREACT_335233. Sphingolipid de novo biosynthesis.

Miscellaneous databases

ChiTaRSiVapb. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiQ3TA54.
ExpressionAtlasiQ3TA54. baseline and differential.
GenevestigatoriQ3TA54.

Family and domain databases

Gene3Di2.60.40.360. 1 hit.
InterProiIPR000535. MSP_dom.
IPR008962. PapD-like.
IPR016763. VAP.
IPR030226. VapB.
[Graphical view]
PANTHERiPTHR10809. PTHR10809. 1 hit.
PTHR10809:SF12. PTHR10809:SF12. 1 hit.
PfamiPF00635. Motile_Sperm. 1 hit.
[Graphical view]
SUPFAMiSSF49354. SSF49354. 1 hit.
PROSITEiPS50202. MSP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NODImported.
    Tissue: Activated spleenImported.

Entry informationi

Entry nameiQ3TA54_MOUSE
AccessioniPrimary (citable) accession number: Q3TA54
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 1, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.