Cyth3

Functionⁱ

GO - Molecular functionⁱ

ARF guanyl-nucleotide exchange factor activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of ARF protein signal transduction Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Cytohesin 3Imported Submitted name: Pleckstrin homology, Sec7 and coiled-coil domains 3, isoform CRA_bImported
Gene namesⁱ	Name:Cyth3Imported Synonyms:Pscd3Imported ORF Names:rCG_42700Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus

Organism-specific databases

Rat genome database More...RGDⁱ	620399. Cyth3.

RGDⁱ

620399. Cyth3.

Interactionⁱ

GO - Molecular functionⁱ

ARF guanyl-nucleotide exchange factor activity Source: InterPro

View the complete GO annotation on QuickGO ...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	59 – 246	SEC7InterPro annotationAdd BLAST		188
Domainⁱ	264 – 380	PHInterPro annotationAdd BLAST		117

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	24 – 58	Sequence analysisAdd BLAST		35

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0930. Eukaryota. COG5307. LUCA.
HOVERGENⁱ	HBG002647.
KEGG Orthology (KO) More...KOⁱ	K18441.

Family and domain databases

Gene3Dⁱ	1.10.1000.11. 1 hit. 2.30.29.30. 1 hit.
InterProⁱ	View protein in InterPro IPR011993. PH-like_dom_sf. IPR001849. PH_domain. IPR023394. Sec7_C_sf. IPR000904. Sec7_dom. IPR035999. Sec7_dom_sf.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00169. PH. 1 hit. PF01369. Sec7. 1 hit.
SMARTⁱ	View protein in SMART SM00233. PH. 1 hit. SM00222. Sec7. 1 hit.
SUPFAMⁱ	SSF48425. SSF48425. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50003. PH_DOMAIN. 1 hit. PS50190. SEC7. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q3T1J6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDEGGGGEGG SVPEDLSLEE REELLDIRRR KKELIDDIER LKYEIAEVMT 
        60         70         80         90        100
EIDNLTSVEE SKTTQRNKQI AMGRKKFNMD PKKGIQFLIE NDLLQSSPED 
       110        120        130        140        150
VAQFLYKGEG LNKTVIGDYL GERDDFNIKV LQAFVELHEF ADLNLVQALR 
       160        170        180        190        200
QFLWSFRLPG EAQKIDRMME AFASRYCLCN PGVFQSTDTC YVLSFAIIML 
       210        220        230        240        250
NTSLHNHNVR DKPTAERFIT MNRGINEGGD LPEELLRNLY ESIKNEPFKI 
       260        270        280        290        300
PEDDGNDLTH TFFNPDREGW LLKLGGRVKT WKRRWFILTD NCLYYFEYTT 
       310        320        330        340        350
DKEPRGIIPL ENLSIREVED PRKPNCFELY NPSHKGQVIK ACKTEADGRV 
       360        370        380        390 
VEGNHVVYRI SAPSPEEKEE WMKSIKASIS RDPFYDMLAT RKRRIANKK

Length:399

Mass (Da):46,280

Last modified:October 11, 2005 - v1

Checksum:ⁱ00F7FEB9C3849157

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC101884 mRNA. Translation: AAI01885.1. CH474012 Genomic DNA. Translation: EDL89657.1. CH474012 Genomic DNA. Translation: EDL89660.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_446364.2. NM_053912.2.
UniGeneⁱ	Rn.10673.

Genome annotation databases

GeneIDⁱ	116693.
KEGGⁱ	rno:116693.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q3T1J6	O08967 Q3TXK1 A0A1U7R5Q6	Mus musculus (Mouse) Mesocricetus auratus (Golden hamster)	399	UniRef100_O08967	Cluster: Cytohesin-3	4

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q3T1J6	O08967 Q3TXK1 A0A1U7R5Q6 UPI0006D90B52 G1N890 UPI000490124A UPI000523E1F6 UPI00090701F3 UPI000A31B23D UPI000BAA3285 +101	Mus musculus (Mouse) Mesocricetus auratus (Golden hamster) Bos mutus (wild yak) Meleagris gallopavo (Wild turkey) Oryctolagus cuniculus (Rabbit) Chaetura pelagica (Chimney swift) Alligator mississippiensis (American alligator) Mus caroli (Ryukyu mouse) (Ricefield mouse) Canis lupus familiaris (Dog) (Canis familiaris) Falco cherrug (Saker falcon) And more	399	UniRef90_O08967	Cluster: Cytohesin-3	112

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q3T1J6	O08967 Q3TXK1 A0A1U7R5Q6 UPI0006D90B52 UPI000490124A G1N890 UPI00090701F3 UPI000523E1F6 UPI000529C433 UPI000A31B23D +257	Mus musculus (Mouse) Mesocricetus auratus (Golden hamster) Bos mutus (wild yak) Oryctolagus cuniculus (Rabbit) Meleagris gallopavo (Wild turkey) Alligator mississippiensis (American alligator) Chaetura pelagica (Chimney swift) Chlamydotis macqueenii (Macqueen's bustard) Mus caroli (Ryukyu mouse) (Ricefield mouse) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) And more	399	UniRef50_O08967	Cluster: Cytohesin-3	268

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC101884 mRNA. Translation: AAI01885.1. CH474012 Genomic DNA. Translation: EDL89657.1. CH474012 Genomic DNA. Translation: EDL89660.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_446364.2. NM_053912.2.
UniGeneⁱ	Rn.10673.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	116693.
KEGGⁱ	rno:116693.

Organism-specific databases

CTDⁱ	9265.
Rat genome database More...RGDⁱ	620399. Cyth3.

Phylogenomic databases

eggNOGⁱ	KOG0930. Eukaryota. COG5307. LUCA.
HOVERGENⁱ	HBG002647.
KEGG Orthology (KO) More...KOⁱ	K18441.

Family and domain databases

Gene3Dⁱ	1.10.1000.11. 1 hit. 2.30.29.30. 1 hit.
InterProⁱ	View protein in InterPro IPR011993. PH-like_dom_sf. IPR001849. PH_domain. IPR023394. Sec7_C_sf. IPR000904. Sec7_dom. IPR035999. Sec7_dom_sf.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00169. PH. 1 hit. PF01369. Sec7. 1 hit.
SMARTⁱ	View protein in SMART SM00233. PH. 1 hit. SM00222. Sec7. 1 hit.
SUPFAMⁱ	SSF48425. SSF48425. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50003. PH_DOMAIN. 1 hit. PS50190. SEC7. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q3T1J6_RAT
Accessionⁱ	Q3T1J6Primary (citable) accession number: Q3T1J6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 11, 2005
	Last sequence update:	October 11, 2005
	Last modified:	March 28, 2018
	This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q3T1J6 (Q3T1J6_RAT)

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Cytohesin 3

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q3T1J6 (Q3T1J6_RAT)

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Cytohesin 3

Cyth3

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ