Cyth3

Functionⁱ

GO - Molecular functionⁱ

ARF guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processⁱ

regulation of ARF protein signal transduction Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Cytohesin 3Imported Submitted name: Pleckstrin homology, Sec7 and coiled-coil domains 3, isoform CRA_bImported
Gene namesⁱ	Name:Cyth3Imported Synonyms:Pscd3Imported ORF Names:rCG_42700Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus

Organism-specific databases

Rat genome database More...RGDⁱ	620399. Cyth3.

RGDⁱ

620399. Cyth3.

Structureⁱ

3D structure databases

SMRⁱ	Q3T1J6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	59 – 246	SEC7InterPro annotationAdd BLAST		188
Domainⁱ	264 – 380	PHInterPro annotationAdd BLAST		117

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	24 – 58	Sequence analysisAdd BLAST		35

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0930. Eukaryota. COG5307. LUCA.
HOVERGENⁱ	HBG002647.
KEGG Orthology (KO) More...KOⁱ	K18441.

Family and domain databases

Gene3Dⁱ	1.10.1000.11. 1 hit. 2.30.29.30. 1 hit.
InterProⁱ	View protein in InterPro IPR011993. PH_dom-like. IPR001849. PH_domain. IPR023394. Sec7_alpha_orthog. IPR000904. Sec7_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00169. PH. 1 hit. PF01369. Sec7. 1 hit.
SMARTⁱ	View protein in SMART SM00233. PH. 1 hit. SM00222. Sec7. 1 hit.
SUPFAMⁱ	SSF48425. SSF48425. 1 hit. SSF50729. SSF50729. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50003. PH_DOMAIN. 1 hit. PS50190. SEC7. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q3T1J6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDEGGGGEGG SVPEDLSLEE REELLDIRRR KKELIDDIER LKYEIAEVMT 
        60         70         80         90        100
EIDNLTSVEE SKTTQRNKQI AMGRKKFNMD PKKGIQFLIE NDLLQSSPED 
       110        120        130        140        150
VAQFLYKGEG LNKTVIGDYL GERDDFNIKV LQAFVELHEF ADLNLVQALR 
       160        170        180        190        200
QFLWSFRLPG EAQKIDRMME AFASRYCLCN PGVFQSTDTC YVLSFAIIML 
       210        220        230        240        250
NTSLHNHNVR DKPTAERFIT MNRGINEGGD LPEELLRNLY ESIKNEPFKI 
       260        270        280        290        300
PEDDGNDLTH TFFNPDREGW LLKLGGRVKT WKRRWFILTD NCLYYFEYTT 
       310        320        330        340        350
DKEPRGIIPL ENLSIREVED PRKPNCFELY NPSHKGQVIK ACKTEADGRV 
       360        370        380        390 
VEGNHVVYRI SAPSPEEKEE WMKSIKASIS RDPFYDMLAT RKRRIANKK

Length:399

Mass (Da):46,280

Last modified:October 11, 2005 - v1

Checksum:ⁱ00F7FEB9C3849157

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC101884 mRNA. Translation: AAI01885.1. CH474012 Genomic DNA. Translation: EDL89657.1. CH474012 Genomic DNA. Translation: EDL89660.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_446364.2. NM_053912.2.
UniGeneⁱ	Rn.10673.

Genome annotation databases

GeneIDⁱ	116693.
KEGGⁱ	rno:116693.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC101884 mRNA. Translation: AAI01885.1. CH474012 Genomic DNA. Translation: EDL89657.1. CH474012 Genomic DNA. Translation: EDL89660.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_446364.2. NM_053912.2.
UniGeneⁱ	Rn.10673.

3D structure databases

SMRⁱ	Q3T1J6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	116693.
KEGGⁱ	rno:116693.

Organism-specific databases

CTDⁱ	9265.
Rat genome database More...RGDⁱ	620399. Cyth3.

Phylogenomic databases

eggNOGⁱ	KOG0930. Eukaryota. COG5307. LUCA.
HOVERGENⁱ	HBG002647.
KEGG Orthology (KO) More...KOⁱ	K18441.

Family and domain databases

Gene3Dⁱ	1.10.1000.11. 1 hit. 2.30.29.30. 1 hit.
InterProⁱ	View protein in InterPro IPR011993. PH_dom-like. IPR001849. PH_domain. IPR023394. Sec7_alpha_orthog. IPR000904. Sec7_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00169. PH. 1 hit. PF01369. Sec7. 1 hit.
SMARTⁱ	View protein in SMART SM00233. PH. 1 hit. SM00222. Sec7. 1 hit.
SUPFAMⁱ	SSF48425. SSF48425. 1 hit. SSF50729. SSF50729. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50003. PH_DOMAIN. 1 hit. PS50190. SEC7. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q3T1J6_RAT
Accessionⁱ	Q3T1J6Primary (citable) accession number: Q3T1J6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 11, 2005
	Last sequence update:	October 11, 2005
	Last modified:	July 5, 2017
	This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q3T1J6 (Q3T1J6_RAT)

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Cytohesin 3

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q3T1J6 (Q3T1J6_RAT)

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Cytohesin 3

Cyth3

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ