Cyth3

Functionⁱ

GO - Molecular functionⁱ

ARF guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processⁱ

regulation of ARF protein signal transduction Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Cytohesin 3Imported Automatic assertion inferred from database entriesⁱ EMBL:AAI01885.1 Submitted name: Pleckstrin homology, Sec7 and coiled-coil domains 3, isoform CRA_bImported Automatic assertion inferred from database entriesⁱ EMBL:EDL89657.1
Gene namesⁱ	Name:Cyth3Imported Automatic assertion inferred from database entriesⁱ EMBL:AAI01885.1 RGD:620399 Synonyms:Pscd3Imported Automatic assertion inferred from database entriesⁱ EMBL:EDL89657.1 ORF Names:rCG_42700Imported Automatic assertion inferred from database entriesⁱ EMBL:EDL89657.1
Organismⁱ	Rattus norvegicus (Rat)Imported Automatic assertion inferred from database entriesⁱ EMBL:AAI01885.1
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Organism-specific databases

RGDⁱ	620399. Cyth3.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000001412.

STRINGⁱ

10116.ENSRNOP00000001412.

Structureⁱ

3D structure databases

SMRⁱ	Q3T1J6. Positions 63-397.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Domainⁱ	59 – 246	188	SEC7InterPro annotation Automatic assertion inferred from signature matchⁱ PROSITE:PS50190			Add BLAST
Domainⁱ	264 – 380	117	PHInterPro annotation Automatic assertion inferred from signature matchⁱ PROSITE:PS50003			Add BLAST

Coiled coil

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Coiled coilⁱ	24 – 58	35	Sequence analysis Automatic assertion according to rulesⁱ SAM:Coils			Add BLAST

Sequence similaritiesⁱ

Contains 1 PH domain.UniRule annotation

Contains SEC7 domain.SAAS annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0930. Eukaryota. COG5307. LUCA.
HOVERGENⁱ	HBG002647.
KOⁱ	K18441.

Family and domain databases

Gene3Dⁱ	1.10.1000.11. 1 hit. 2.30.29.30. 1 hit.
InterProⁱ	IPR011993. PH_dom-like. IPR001849. PH_domain. IPR023394. Sec7_alpha_orthog. IPR000904. Sec7_dom. [Graphical view]
Pfamⁱ	PF00169. PH. 1 hit. PF01369. Sec7. 1 hit. [Graphical view]
SMARTⁱ	SM00233. PH. 1 hit. SM00222. Sec7. 1 hit. [Graphical view]
SUPFAMⁱ	SSF48425. SSF48425. 1 hit. SSF50729. SSF50729. 1 hit.
PROSITEⁱ	PS50003. PH_DOMAIN. 1 hit. PS50190. SEC7. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Complete.

Q3T1J6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDEGGGGEGG SVPEDLSLEE REELLDIRRR KKELIDDIER LKYEIAEVMT 
        60         70         80         90        100
EIDNLTSVEE SKTTQRNKQI AMGRKKFNMD PKKGIQFLIE NDLLQSSPED 
       110        120        130        140        150
VAQFLYKGEG LNKTVIGDYL GERDDFNIKV LQAFVELHEF ADLNLVQALR 
       160        170        180        190        200
QFLWSFRLPG EAQKIDRMME AFASRYCLCN PGVFQSTDTC YVLSFAIIML 
       210        220        230        240        250
NTSLHNHNVR DKPTAERFIT MNRGINEGGD LPEELLRNLY ESIKNEPFKI 
       260        270        280        290        300
PEDDGNDLTH TFFNPDREGW LLKLGGRVKT WKRRWFILTD NCLYYFEYTT 
       310        320        330        340        350
DKEPRGIIPL ENLSIREVED PRKPNCFELY NPSHKGQVIK ACKTEADGRV 
       360        370        380        390 
VEGNHVVYRI SAPSPEEKEE WMKSIKASIS RDPFYDMLAT RKRRIANKK

Length:399

Mass (Da):46,280

Last modified:October 11, 2005 - v1

Checksum:ⁱ00F7FEB9C3849157

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC101884 mRNA. Translation: AAI01885.1. CH474012 Genomic DNA. Translation: EDL89657.1. CH474012 Genomic DNA. Translation: EDL89660.1.
RefSeqⁱ	NP_446364.2. NM_053912.2.
UniGeneⁱ	Rn.10673.

Genome annotation databases

GeneIDⁱ	116693.
KEGGⁱ	rno:116693.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC101884 mRNA. Translation: AAI01885.1. CH474012 Genomic DNA. Translation: EDL89657.1. CH474012 Genomic DNA. Translation: EDL89660.1.
RefSeqⁱ	NP_446364.2. NM_053912.2.
UniGeneⁱ	Rn.10673.

3D structure databases

SMRⁱ	Q3T1J6. Positions 63-397.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000001412.

STRINGⁱ

10116.ENSRNOP00000001412.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	116693.
KEGGⁱ	rno:116693.

Organism-specific databases

CTDⁱ	9265.
RGDⁱ	620399. Cyth3.

Phylogenomic databases

eggNOGⁱ	KOG0930. Eukaryota. COG5307. LUCA.
HOVERGENⁱ	HBG002647.
KOⁱ	K18441.

Family and domain databases

Gene3Dⁱ	1.10.1000.11. 1 hit. 2.30.29.30. 1 hit.
InterProⁱ	IPR011993. PH_dom-like. IPR001849. PH_domain. IPR023394. Sec7_alpha_orthog. IPR000904. Sec7_dom. [Graphical view]
Pfamⁱ	PF00169. PH. 1 hit. PF01369. Sec7. 1 hit. [Graphical view]
SMARTⁱ	SM00233. PH. 1 hit. SM00222. Sec7. 1 hit. [Graphical view]
SUPFAMⁱ	SSF48425. SSF48425. 1 hit. SSF50729. SSF50729. 1 hit.
PROSITEⁱ	PS50003. PH_DOMAIN. 1 hit. PS50190. SEC7. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

Q3T1J6_RAT

Accessionⁱ

Primary (citable) accession number: Q3T1J6

Entry historyⁱ

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Unreviewed (UniProtKB/TrEMBL)

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB - Q3T1J6 (Q3T1J6_RAT)

UniProt

Q3T1J6 - Q3T1J6_RAT

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Cytohesin 3

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Similar proteinsⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q3T1J6 (Q3T1J6_RAT)

UniProt

Q3T1J6 - Q3T1J6_RAT

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Cytohesin 3

Cyth3

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<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ