Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3T1J2

- MBOA2_RAT

UniProt

Q3T1J2 - MBOA2_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Membrane-bound O-acyltransferase domain-containing protein 2

Gene

Mboat2

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei341 – 3411By similarity
Active sitei372 – 3721By similarity

GO - Molecular functioni

  1. transferase activity, transferring acyl groups Source: UniProtKB-KW

GO - Biological processi

  1. phospholipid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

ReactomeiREACT_199127. Acyl chain remodelling of PC.
REACT_199147. Acyl chain remodelling of PE.
UniPathwayiUPA00085.

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane-bound O-acyltransferase domain-containing protein 2 (EC:2.3.-.-)
Short name:
O-acyltransferase domain-containing protein 2
Gene namesi
Name:Mboat2
Synonyms:Oact2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Unplaced

Organism-specific databases

RGDi1305798. Mboat2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei22 – 4221HelicalSequence AnalysisAdd
BLAST
Transmembranei61 – 8121HelicalSequence AnalysisAdd
BLAST
Transmembranei88 – 10821HelicalSequence AnalysisAdd
BLAST
Transmembranei184 – 20421HelicalSequence AnalysisAdd
BLAST
Transmembranei236 – 25621HelicalSequence AnalysisAdd
BLAST
Transmembranei288 – 30518HelicalSequence AnalysisAdd
BLAST
Transmembranei365 – 38521HelicalSequence AnalysisAdd
BLAST
Transmembranei415 – 43521HelicalSequence AnalysisAdd
BLAST
Transmembranei443 – 46321HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 519519Membrane-bound O-acyltransferase domain-containing protein 2PRO_0000273022Add
BLAST

Proteomic databases

PaxDbiQ3T1J2.

Expressioni

Gene expression databases

ExpressionAtlasiQ3T1J2. baseline.
GenevestigatoriQ3T1J2.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009018.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5202.
HOGENOMiHOG000015994.
HOVERGENiHBG058823.
InParanoidiQ3T1J2.
KOiK13517.
OrthoDBiEOG73Z2SW.
PhylomeDBiQ3T1J2.
TreeFamiTF314906.

Family and domain databases

InterProiIPR004299. MBOAT_fam.
[Graphical view]
PfamiPF03062. MBOAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3T1J2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATTSTTGST LLQPLSNAVQ LPIDQVNFVV CQLFALLAAV WFRTYLHSSK
60 70 80 90 100
TSSFIRHVVA TLLGLYLAFF CFGWYALHFL VQSGISYCIM IIAGVESMHQ
110 120 130 140 150
CCFVFALGYL SVCQITRVYI FDYGQYSADF SGPMMIITQK ITSLAYEIHD
160 170 180 190 200
GMFRKDEELT PSQRGLAVRR MPSLLEYVSY TCNFMGILAG PLCSYKDYIA
210 220 230 240 250
FIEGRASHMA QSGENGKEEQ HGKAEPSPNA AVTEKLLVCG LSLLFHLTIS
260 270 280 290 300
SMLPVEYNID EHFQATASWP TKATYLYVSL LAARPKYYFA WTLADAINNA
310 320 330 340 350
AGFGFRGYDK NGVARWDLIS NLRIQQIEMS TSFKMFLDNW NIQTALWLKR
360 370 380 390 400
VCYERATFSP TVQTFFLSAI WHGVYPGYYL TFLTGVLMTL AARAVRNNFR
410 420 430 440 450
HYFVEPPQLK LFYDIITWAA TQITISYTVV PFVLLSINPS FTFYRSWYYC
460 470 480 490 500
LHICSILVLL LLPVKKSPRK KNTEENAQPS WAKKFDEREN SLGQNSFSMM
510
NNVCNQNQDT GSRHSALTQ
Length:519
Mass (Da):59,001
Last modified:January 23, 2007 - v2
Checksum:iD5CAFBD16F7642B3
GO

Sequence cautioni

The sequence BC101889 differs from that shown. Reason: Frameshift at position 41. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03049793 Genomic DNA. No translation available.
AABR03054282 Genomic DNA. No translation available.
AABR03052483 Genomic DNA. No translation available.
AABR03050975 Genomic DNA. No translation available.
AABR03049616 Genomic DNA. No translation available.
BC101889 mRNA. No translation available.
RefSeqiNP_001101486.2. NM_001108016.2.
UniGeneiRn.35322.

Genome annotation databases

GeneIDi313997.
KEGGirno:313997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR03049793 Genomic DNA. No translation available.
AABR03054282 Genomic DNA. No translation available.
AABR03052483 Genomic DNA. No translation available.
AABR03050975 Genomic DNA. No translation available.
AABR03049616 Genomic DNA. No translation available.
BC101889 mRNA. No translation available.
RefSeqi NP_001101486.2. NM_001108016.2.
UniGenei Rn.35322.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000009018.

Proteomic databases

PaxDbi Q3T1J2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 313997.
KEGGi rno:313997.

Organism-specific databases

CTDi 129642.
RGDi 1305798. Mboat2.

Phylogenomic databases

eggNOGi COG5202.
HOGENOMi HOG000015994.
HOVERGENi HBG058823.
InParanoidi Q3T1J2.
KOi K13517.
OrthoDBi EOG73Z2SW.
PhylomeDBi Q3T1J2.
TreeFami TF314906.

Enzyme and pathway databases

UniPathwayi UPA00085 .
Reactomei REACT_199127. Acyl chain remodelling of PC.
REACT_199147. Acyl chain remodelling of PE.

Miscellaneous databases

NextBioi 667109.
PROi Q3T1J2.

Gene expression databases

ExpressionAtlasi Q3T1J2. baseline.
Genevestigatori Q3T1J2.

Family and domain databases

InterProi IPR004299. MBOAT_fam.
[Graphical view ]
Pfami PF03062. MBOAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown Norway.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Prostate.

Entry informationi

Entry nameiMBOA2_RAT
AccessioniPrimary (citable) accession number: Q3T1J2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 59 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3